Respiratory infections are among the most common causes of morbidity and mortality worldwide. These infections present a special challenge to physicians for several reasons, including of the recent disasters caused by severe acute respiratory syndrome (SARS) and bird and swine influenza, the increase in viral and bacterial resistance to currently available anti-microbial drugs, the increased frequency of new viral lung infections in clinical practice, and the worldwide emergence of deadly drug-resistant forms of TB. For these reasons, it is important for infectious disease specialists to have an overview of emerging respiratory infections.

"Respiratory infections are one of the most common causes of morbidity and mortality worldwide. As we enter the twenty-first century, several landmark events are unfolding in the area of respiratory infections. Some of these, by assuming the form of formidable disasters, have abruptly claimed lives and led to economic loss. Examples include severe acute respiratory syndrome (SARS) and bird and swine influenza. Viral and bacterial resistance to currently available antimicrobial drugs is thwarting efforts in the management of influenza and pulmonary sepsis. Newer and emerging viral lung infections are seen more frequently in clinical practice, including post-transplant viral infections other than cytomegalovirus and Epstein-Barr virus. The frequency and diversity of serious fungal infections are increasing. Persons who are severely immunocompromised are particularly vulnerable to infection from unusual molds and yeasts that are often found naturally in the environment. Other respiratory infections pose continuous health care challenges. Examples include the changing demography of tuberculosis (TB) and emerging deadly drug-resistant forms of TB worldwide. Pediatric TB and elderly TB are on the rise and the problem of coinfection with HIV is proving difficult to diagnose and manage. Anti-tumor necrosis factor (TNF)-a therapy for autoimmune conditions results in reactivation of TB. In addition, occupational lung diseases due to airborne microbes constitute another problematic issue. Protozoal and helminthic lung infestations continue to be important clinical problems in many parts of the world. This issue of Infectious Diseases Clinics of North America is aimed at giving an up-todate and comprehensive overview of emerging respiratory infections in the twenty-first century through 14 articles written by authoritative experts from all around the globe." - p. xiii.

In the past two decades, several pandemics have ravaged the globe, giving us several lessons on infectious disease epidemiology, the importance of initial detection and characterization of outbreak viruses, the importance of viral epidemic prevention steps, and the importance of modern vaccines. Pandemic Outbreaks in the Twenty-First Century: Epidemiology, Pathogenesis, Prevention, and Treatment summarizes the improvements in the 21st century to overcome / prevent / treat global pandemic with future prospective. Divided into 9 chapters, the book begins with an in-depth introduction to the lessons learned from the first pandemic of the 21st century. It describes the history, present and future in terms of detection, prevention and treatment. Followed by chapters on the outbreak, treatment strategies and clinical management of several infectious diseases like MERS, SARD and COVID 19, Pandemic Outbreaks in the Twenty-First Century: Epidemiology, Pathogenesis, Prevention, and Treatment, presents chapters on immunotherapies and vaccine technologies to combat pandemic outbreak and challenges. The book finishes with a chapter on the current knowledge and technology to control pandemic outbreaks. All are presented in a practical short format, making this volume a valuable resource for very broad academic audience. Provides insight to the lessons learned from past pandemics Gives recommendations, future direction in terms of detection, prevention and treatment of pandemics Guides readers through the status and recent developments of vaccines to overcome or prevent pandemics Shows how to enhance the host innate immunity in infectious diseases Includes a chapter on immunotherapies to combat pandemic outbreaks

This volume provides guidance and answers to frequently asked questions in infectious diseases, thus facilitating improved patient care, prudent and cost effective management and investigation of these disorders. Other more complicated but less common conditions are also reviewed. Uniquely, this volume directly discusses several controversies regarding infectious diseases from the 21st century.

Current data and trends in morbidity and mortality for the sub-Saharan Region as presented in this new edition reflect the heavy toll that HIV/AIDS has had on health indicators, leading to either a stalling or reversal of the gains made, not just for communicable disorders, but for cancers, as well as mental and neurological disorders.

Global Virology, Volume III: Virology in the 21st Century examines work that has been undertaken, or is planned, in several fields of virology, in an effort to promote current and future work, research, and health. Fields and methods addressed include virology, immunology, space research, astrovirology/astrobiology, plasmids, swarm intelligence, bioinformatics, data-mining, machine learning, neural networks, critical equations, and advances in biohazard biocontainment. Novel and forward-looking methods, techniques, and approaches in research and development are presented by experts in the field.