This second edition is substantially expanded, with broader and deeper coverage. Includes new chapters on the focal and multifocal electroretinogram and the pattern ERG. Also covers visual evoked potential, pattern dystrophies, North Carolina macular dystrophy, progressive bifocal maculardystrophy, sheen retinal dystrophies, neuronal ceroid lipofuscionoses, retinal degeneration with spinocerebellar ataxia, enhanced S-cone syndrome, and more.

The long-awaited second edition of an authoritative reference on electrophysiologic vision testing, including detailed information on techniques and problems, basic physiology and anatomy, theoretical concepts, and clinical findings; with extensive new material. This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science. The contributions not only cover new information—important material that is likely to become more important in the next decade—but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.

This book provides an analytical and thorough review of clinical electrophysiology of vision, and the progress made in the field in the past decade. Handbook of Clinical Electrophysiology of Vision is designed to aid the readers in understanding the types of electrophysiologic tests that should be used in specific diseases, how to explain the results of these exams, and how to perform the tests of clinical electrophysiology of vision. Concise in format, the Handbook of Clinical Electrophysiology of Vision is divided into two sections that discuss a wide range of relevant topics, such as technology of electroretinography, electrooculography, visual evoked potential, characteristics of electroretinography in retinal diseases, and the characteristics of optic nerve diseases. Part one begins with a discussion on the basic theory of electrophysiology of vision, illustrating physiologic sources of electrophysiological responses, the techniques of the recording, and analysis of electrophysiologic signals. Part two then dives into the clinical application of electrophysiology of vision, and subsequently summarizes the characteristics of the electrophysiological signals in a number of disorders of retina and optic nerve. Written by experts in the field, Handbook of Clinical Electrophysiology of Vision is an invaluable resource for ophthalmologists, optometrists, electrophysiologists, residents, fellows, researchers, technicians and students in ophthalmology, optometry and vision science.

This book takes a clinical approach to the patient with a genetic disease that affects the eye. The chapters on particular types of diseases follow the same organizational format, covering history, pathogenesis and etiology, epidemiology, classification, clinical manifestations and diagnosis, and treatment. The recent progress achieved in the molecular genetics of eye disease is fully reflected throughout the book. It is written by leading experts in the field and provides clinical, molecular genetic and management information on common and rare diseases. The chapters are heavily illustrated and provide a good Atlas for the practicing ophthalmologist or geneticist.

Examines electrophysiologic testing in disorders of the retina, optic nerve and visual pathway. The book includes references for further reading and a self-study examination.

Pediatric Neuroophthalmology details the diagnostic criteria, current concepts of pathogenesis, neuroradiological correlates, and clinical management of a large group of neuroophthalmic disorders that present in childhood. Surprisingly distinct from neuroophthalmic disorders afflicting adults, this set of diseases falls between the cracks of most ophthalmology training, and thus, warrants a practical, clinical guide for the practitioner in ophthalmology - the neuroophthalmologist, pediatric ophthalmologist, general ophthalmologist - as well as neurologists and for residents. The authors, leading pediatric ophthalmologists, have taken this difficult subject matter and developed an accessible, user-friendly manual with a detailed approach to the recognition, differential diagnosis, and management of pediatric neuroophthalmologic disorders.

Featuring over 250 illustrations, this detailed full-color textbook provides up-to-date information on the use of fundus autofluorescence imaging in evaluation of retinal disease. Chapters describe the techniques available to image and quantify fundus autofluorescence and the autofluorescence patterns observed in the healthy eye and in various retinal diseases. Emphasis is on the value of fundus autofluorescence as a diagnostic and prognostic tool and its clinical utility in the context of other imaging techniques, such as fluorescein and indocyanine green angiography and optical coherence tomography. Each chapter also discusses the value of fundus autofluorescence in understanding the pathogenesis of the condition, and provides a comprehensive update on all aspects of the condition. A companion Website will offer the fully searchable text and an image bank.