In this book, the authors present current research in the study of the synthesis, uses and environmental concerns of EDTA. Topics discussed include the symbiotic and synergic effects in amide and ester derivatives of EDTA; photo- or radiation-induced degradation of EDTA and its complexes of heavy metals; the use of EDTA root conditioning in regenerative procedures of periodontal tissues; effects of EDTA on adsorption behaviour of cadmium onto natural freshwater surface coatings; and the environmental concerns and remedies in the management of EDTA-containing aqueous effluent.

EDTA Titrations: An Introduction to Theory and Practice, Second Edition considers the theoretical background, full procedural details, and some practical applications of EDTA titrations. Ethylenediaamine tetra-acetic acid (EDTA) has risen from an obscure chemical compound to the most widely used organic reagent. This book is composed of 21 chapters. The opening chapters present the general theoretical foundations of EDTA titrations. The subsequent chapters describe the properties of EDTA, such as the stability constants, titration curves, selectivity, and masking effect. These topics are followed by discussions on titration types, standard solutions, and reagents. The remaining chapters cover some of the practical applications of EDTA titrations. This book is directed toward students with advanced courses in analytical and organic chemistry.

Environmental Chemistry is a relatively young science. Interest in this subject, however, is growing very rapidly and, although no agreement has been reached as yet about the exact content and limits of this interdisciplinary subject, there appears to be increasing interest in seeing environmental topics which are based on chemistry embodied in this subject. One of the first objectives of Environ mental Chemistry must be the study of the environment and of natural chemical processes which occur in the environment. A major purpose of this series on Environmental Chemistry, therefore, is to present a reasonably uniform view of various aspects of the chemistry of the environment and chemical reactions occuring in the environment. The industrial activities of man have given a new dimension to Environ mental Chemistry. We have now synthesized and described over five million chemical compounds and chemical industry produces about one hundred and fifty million tons of synthetic chemicals annually. We ship billions of tons of oil per year and through mining operations and other geophysical modifications, large quantities of inorganic and organic materials are released from their natural deposits. Cities and metropolitan areas of up to 15 million inhabitants produce large quantities ofwaste in relatively small and confined areas. Much of the chemical products and was te products of modern society are released into the environment either during production, storage, transport, use or ultimate disposal. These released materials participate in natural cycles and reactions and frequently lead to interference and disturbance of natural systems.

Analytical Applications of EDTA and Related Compounds examines the analytical applications of ethylenediaminetetra-acetic acid (EDTA) and related compounds. This book also considers the "passive role of these substances, that is, their screening (masking) properties, which greatly improve the selectivity of the reactions in common use. This text consists of six chapters organized into two sections. The first part deals with the uses of EDTA and its derivatives in some fields of chemical analysis. After providing an overview of the history behind the development of EDTA as an analytical reagent, this book discusses to the nature of equilibria of complexes and the methods used in their investigation. The next chapter is dedicated to the reactions of "classical gravimetric analysis, including the precipitation reactions by means of organic reagents. The chapter on colorimetry includes a section on "colored complexing agents, which can be used also in colorimetric determinations of some elements. This text concludes by evaluating the use of EDTA as a masking agent in colorimetry. This book will be of interest to students and practitioners working in analytical chemistry and related disciplines, including polarography, chromatography, electrophoresis, flame photometry, and qualitative analysis.

Critical Survey of Stability Constants of EDTA Complexes focuses on the computations, values, and characteristics of stability constants. The book emphasizes that for a critical discussion of experimentally determined stability constants, it is important to consider the precision of the values that manifests the self-consistency of the constant, taking into consideration the random errors. The publication reviews the stability constants of metal complexes. The numerical calculations affirm the reactions and transformations of metal ions when exposed to varying conditions. The text also presents a list of enthalpies of reactions with (ethylenedinitrito)tetra-acetic acid (EDTA) obtained by direct calorimetric measurements. The book also notes that in order to identify reliable metal complex stability constants for a ligand, it is important to know the formation constants of protonated species. The text is a dependable reference for readers wanting to dig deeper into the stability constants of EDTA complexes.

Chelation therapy, based on the intravenous infusion of EDTA, is a highly effective treatment for atherosclerotic cardiovasular disease. Saftey and effectivenss are well documented in clinical studies, all of which to date are supportive of this therapy, and there are no studies showing lack of effectiveness. A strong case is made for the use of this safe, efficacious, and inexpensive therapy before resorting to surgery and other risky and invasive treatments. In this newly revised and extensively updated edition of what has come to be regarded as the definitive textbook on the subject, renowned chelation expert Elmer M. Cranton, M.D., presents the work of the world's leading experts in chelation therapy. "This therapy has been proven effective over and over again in clinical practice," says Dr. Cranton. "More than one million patients have recieved more than twenty million infusions with no serious or lasting adverse effects." In his foreword, Nobel Prize winner Dr. Linus Pauling states, "EDTA chelation therapy makes good sense to me as a chemist and medical researcher. It has a rational scientific basis, and the evidence for clinical benefit seems to be quite strong." Here in a single volume you will learn everything you need to know to responsibly administer and advocate chelation therapy. You will find a coherent scientific rationale, clinical trials demonstating effectiveness, guidelines for saftey, detailed protocols for administration, and techniques for pre- and post-treatment laboratory evalutaion.

This book is written for hospital doctors, nurses, biochemists, medi cal laboratory scientific officers and phlebotomists involved with the biochemical investigation of patients. It is hoped, also, that general practitioners and medical students will find it of help. Whilst the vast majority of biochemical tests assess the level of constituents in blood and urine at a given point in time, an impor tant additional parameter is the assessment of physiological reserve function by means of loading tests, prOlonged fasting, exercise and clearance studies. The protocol and interpretation of response of each of these stress tests form the main basis of the text. An attempt has been made to be reasonably comprehensive in the range of tests described; hence, not only have some rather older ones been re tained, but also some very recently introduced ones included. It is appreciated that practice varies widely from laboratory to labora tory with respect to protocol, sample collection, methodology and quotation of reference ranges, and no doubt also from clinician to clinician, particularly regarding interpretation of results. In paedi atric work, micromethods will demand much smaller volumes of blood than those stated here, which relate generally to adult medi cine. The account, therefore, must be seen as a guide to practice rather than as a recipe; it is in no wayan attempt to standardise procedures, which depend on the local requirements.