ECAB Reviews in Neurology 2013 - E-Book

This volume presents a snapshot of some of the most important ongoing research in cancer. With cancer as the second leading cause of death worldwide, extensive research is going on globally to decipher the molecular mechanism underlying cancer that will help in finding better targets for drug therapy. The book brings together new research on molecular mechanism and cancer therapeutics in one place. With chapters from experts in their respective fields, chapters cover molecular mechanisms, etiology, prognosis, detection, and treatment of cancer. Emphasis has been given to the intricate mechanism behind the deregulation of cell division, disruption of cell cycle check points, mutation in oncogenes and tumor suppressor genes, apoptosis, and erratic cell signaling. The book discusses in detail topics such as angiogenesis and tumor microenvironment, which are increasingly receiving attention, especially in the field of neoplastic vascularization and metastasis. The book also includes chapters detailing the current understanding and the future perspective of cancer stem cells.

Common vestibulocochlear disorders presenting with vertigo contributes significantly to morbidity and mortality. The challenge is to identify the underlying cause of dizziness so as to streamline the treatment and improve quality of life. In day-to-day ENT practice, incidence of dizziness is reported to be 10–15%. It is often associated with a range of otological, neurological and psychiatric disorders. There are fewer subjects in medicine which keep us more confused than vertigo. Dizziness and vertigo may be disturbing and incapacitating causing problems to people doing regular or specialized tasks such as driving, operating heavy machinery or flying. As the sensations are hard to describe, patients often use the words "dizziness" and "Vertigo" interchangeably and inconsistently. Patients with the same underlying disorder might describe the symptoms very differently and might also differently describe the same "dizzy" event depending upon how the question is directed. The aim of this book is to explore the experience and learning of some of the eminent medical professionals, develop relevant updates, and make them easily available for utilization by the Indian clinical practitioners.

Venous thromboembolism is a common and potentially lethal disease. Patients who have pulmonary embolism are at especially high risk for death. Sudden death is often the first clinical manifestation. Only a reduction in the incidence of venous thromboembolism can reduce sudden death owing to pulmonary embolism and venous stasis syndrome owing to deep vein thrombosis. Improvement in the incidence of venous thromboembolism will require (i) better recognition of persons at risk, (ii) improved estimates of the magnitude of risk, (iii)avoidance of risk exposure when possible, (iv)more widespread use of safe and effective prophylaxis when risk is unavoidable, and (v) targeting of prophylaxis to those persons who will benefit most. Early and timely diagnosis and management of deep vein thrombosis and pulmonary embolism considerably reduces the subsequent morbidity and mortality.

Common vestibular disorders presenting with vertigo contributes significantly to morbidity and mortality. The challenge is to identify the underlying cause of dizziness so as to streamline the treatment and improve quality of life. In day to day ENT practice incidence of dizziness is reported to be 10–15%. It is often associated with a range of otological, neurological, and psychiatric disorder. There are fewer subjects in medicine which keep us more confused than vertigo. Dizziness and vertigo may be disturbing and incapacitating causing problems to people doing regular or specialized tasks such as driving, operating heavy machinery or flying. As the sensations are hard to describe, patients often use the words "dizziness" and "vertigo" interchangeably and inconsistently. Patients with the same underlying disorder might describe the symptoms very differently and might also differently describe the same "dizzy" event depending upon the how the question is directed. The aim of this project is to explore the experience and learning of some of the eminent medical professionals, develop relevant updates, and make them easily available for utilization by the Indian clinical practitioners.

Written specifically for non-sleep medicine specialists, this one-of-a-kind reference guides you through every aspect of this complex field with authoritative advice from Dr. Meir Kryger and other experts. Vibrantly illustrated in full color, it thoroughly covers the types of patients you're most likely to see in the outpatient setting and brings you up to date with the latest treatment methods, both surgical and non-surgical. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. - Complete coverage of the patients you're most likely to encounter, including special populations such as those with COPD, obesity hypoventilation, pregnancy, neuromuscular disorders, stroke, and more. - Specific information on topics of interest to a wide variety of physicians: heart failure and sleep disordered breathing; surgical treatments, including hypoglossal nerve stimulation; oral appliances and the treatment of sleep apnea; home sleep testing; and different types of PAP devices. - Ideal for pulmonologists, otolaryngologists, cardiologists, primary care physicians, dentists, and other healthcare providers who encounter patients with sleep and breathing disorders. - Full-color illustrations throughout, including a profusely illustrated chapter on physical diagnosis.

This volume examines why hospitals collaborate with each other and with other health care actors across borders in Europe. Cross-border hospital collaboration is not a new phenomenon but began to receive increased attention in the first decade of the 21st century in the context of European debates on patient mobility, the impact of European Union (EU) integration on national health systems and the particular situation of border regions. In this context, the role of health care providers stands out: while physically anchored in the health system that funds and regulates them, hospitals in border regions often witness or initiate cross-border movements of patients and health professionals.