This book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first realize they are infertile when they start trying to conceive a child, and there is a possibility that their testes may already exhibit the end stage of testicular autoimmunity, in which lymphocytic inflammation and immunoglobulin deposition in their testes subsided long ago and only the spermatogenic disorder remains. Therefore, autopsy or biopsy for testicular tissues in men before the end stage of testicular autoimmunity and investigations using testicular autoimmunity model animals are needed to determine the epidemiology of testicular autoimmunity. Accordingly, the book discusses “the immunological fragility of testis” with regard to male infertility, reviewing autopsy data in men and presenting experimental data using murine models of autoimmune orchitis that has been induced by immunizing with viable syngeneic testicular germ cells alone. Testicular autoimmunity in animals is also discussed. In summary, the book provides a wealth of valuable information, not only for researchers who are interested in immunologic male infertility, but also for clinical professionals who treat these patients at hospitals.

The two-volume set LNCS 12572 and 1273 constitutes the thoroughly refereed proceedings of the 27th International Conference on MultiMedia Modeling, MMM 2021, held in Prague, Czech Republic, in June2021. Of the 211 submitted regular papers, 40 papers were selected for oral presentation and 33 for poster presentation; 16 special session papers were accepted as well as 2 papers for a demo presentation and 17 papers for participation at the Video Browser Showdown 2021. The papers cover topics such as: multimedia indexing; multimedia mining; multimedia abstraction and summarization; multimedia annotation, tagging and recommendation; multimodal analysis for retrieval applications; semantic analysis of multimedia and contextual data; multimedia fusion methods; multimedia hyperlinking; media content browsing and retrieval tools; media representation and algorithms; audio, image, video processing, coding and compression; multimedia sensors and interaction modes; multimedia privacy, security and content protection; multimedia standards and related issues; advances in multimedia networking and streaming; multimedia databases, content delivery and transport; wireless and mobile multimedia networking; multi-camera and multi-view systems; augmented and virtual reality, virtual environments; real-time and interactive multimedia applications; mobile multimedia applications; multimedia web applications; multimedia authoring and personalization; interactive multimedia and interfaces; sensor networks; social and educational multimedia applications; and emerging trends.

Novel Approaches to Colorectal Cancer, Volume 151 in the Advances in Cancer Research series, is composed of 11 reviews covering state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. The book's chapters were written by recognized experts in the field, and include sections on molecular biomarkers in diagnosis and therapy, the interplay of diet, lifestyle, and the microbiome, early-age onset disease, mutational signature analysis, challenges in early detection, immunotherapy, organoid technology, the role of epigenetic alterations, disparities in minority populations, field carcinogenesis, and cancer as an evolutionary process. Each of these topics provides novel insights and concepts on various aspects of the nature of colorectal cancer, offering new opportunities for the management of a major source of cancer incidence and mortality. - Provides information on the timely nature of the included topics, which represent the most current concepts and approaches in cancer research - Offers outstanding and original reviews on colorectal cancer research - Provides the authority and expertise of the authors, all of whom are highly recognized and conducting state-of-the-art investigations in cancer, with this release focusing on colorectal cancer

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The sixteen-volume set comprising the LNCS volumes 11205-11220 constitutes the refereed proceedings of the 15th European Conference on Computer Vision, ECCV 2018, held in Munich, Germany, in September 2018.The 776 revised papers presented were carefully reviewed and selected from 2439 submissions. The papers are organized in topical sections on learning for vision; computational photography; human analysis; human sensing; stereo and reconstruction; optimization; matching and recognition; video attention; and poster sessions.