Dysimmune Neuropathies provides readers with detailed, basic information that will enable users to recognize and differentiate each neuropathy to adequately guide an investigation and create a treatment plan. An overview of recent progress, avenues for future research, and the desired benefits are also covered. The book highlights the many developments in the field that have occurred in terms of pathophysiological mechanisms, particularly immunological, that have direct implications on treatment strategies. This book is a great reference for trainees, clinicians and researchers specializing in neurology, neuromuscular diseases and neurophysiology. - Encompasses all dysimmune neuropathies - Describes clinical features, epidemiology, pathophysiology and immunology - Provides differential diagnosis - Identifies new investigation techniques

Neuromuscular medicine is constantly advancing in terms of accurate diagnosis, pathophysiology, and treatment. Many disorders that have been discovered within this field are either autoimmune or genetic. This publication provides the latest updates of the more common and treatable autoimmune neuromuscular diseases affecting the spinal cord, peripheral nerves, neuromuscular junction and muscles. The authors, renowned experts in the field, offer clinical presentations as well as the best diagnostic and treatment approach to the readers. The chapters are dealing with acute and chronic neuropathies, nonsystemic vasculitic neuropathy, dysimmune neuropathy and autoimmune autonomic ganglionopathy. Further, disorders such as myasthenia gravis, Lambert-Eaton myasthenic syndrome, idiopathic inflammatory myopathies and stiff person syndrome are discussed.Providing an excellent source of up-to-date information, this publication is highly recommended not only to neurologists, but also to internists, rheumatologists, allergists and immunologists.

A volume in the Handbook of Clinical Neurophysiology series on peripheral neuropathies. The ultimate reference source for clinical neurophysiologists on peripheral neuropathies. Volume in a prestigious series published in association with the International Federation of Clinical Neurophysiology. International contributor list drawn from around the world.

Muscle weakness with ageing is almost inevitable, generally beginning to manifest beyond the age of 40, and is usually unstoppable. It can lead to reduced mobility, increased risk of falling, injury, and even death. But “you’re just getting old” is not a sufficient diagnosis. Specific causes of neuromuscular symptoms may explain progressive muscle weakness, and should be investigated for potential treatment. Muscle Ageing, Inclusion-Body Myositis and Myopathies explores the clinical and pathological expression of muscle weakness in aging persons. Case studies demonstrate how physicians can more accurately diagnose weakening elderly patients and make better management decisions. It also explores sporadic inclusion-body myositis and hereditary inclusion-body myopathies. The former, the most common progressive muscle disease in the over 50s, is frequently under-diagnosed and, with the increasing population of aged individuals, is presenting a greater challenge. This disease of muscle has pathological similarities with the well-known Alzheimer and Parkinson brain diseases. Edited and written by a leading international cast of authors, Muscle Ageing, Inclusion-Body Myositis and Myopathies provides a state-of-the-art guide to ageing-associated neuromuscular disorders. It should be in the hands of all those involved in the care of aging and muscle-weakened patients. Titles of Related Interest Neuromuscular Disorders Tawil and Vennance (eds); ISBN 978-0-470-65456-9 European Handbook of Neurological Management, Vol 1, 2e Gilhus, Barnes, Brainin (eds); ISBN 978-1-4051-8533-2 European Handbook of Neurological Management, Vol 2, 2e Gilhus, Barnes, Brainin (eds); ISBN 978-1-4051-8534-9

This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage. Leading scientists in the field have summarized in short reviews the state of the art of neuroimmunology, with particular emphasis on basic aspects of the regulation of immune responses during demyelinating disorders. The volume will be helpful to neuroimmunologists, but also to clinicians which will find a clear and concise understanding of the main features of neuroinflammatory disease.

This book, the second of three volumes, concentrates on peripheral nervous system disorders. Examining the effects of neurotoxicants on nerve, muscle and the neuromuscular junction, it builds on the scientific principles outlined in volume 1 by looking at the application of the methods discussed, particularly in terms of the evaluation and diagnosis of individual patients and the related process of establishing causation. Neurobehavorial Toxicology, Volume 2 will be of interest to practicing neurologists and neuropsychologists, as well as to occupational medicine physicians and medical toxicologists.