Dynamics of Proteins and Nucleic Acids
Title | Dynamics of Proteins and Nucleic Acids PDF eBook |
Author | J. Andrew McCammon |
Publisher | Cambridge University Press |
Pages | 256 |
Release | 1988-04-29 |
Genre | Science |
ISBN | 9780521356527 |
This book is a self-contained introduction to the theory of atomic motion in proteins and nucleic acids. An understanding of such motion is essential because it plays a crucially important role in biological activity. The authors, both of whom are well known for their work in this field, describe in detail the major theoretical methods that are likely to be useful in the computer-aided design of drugs, enzymes and other molecules. A variety of theoretical and experimental studies is described and these are critically analyzed to provide a comprehensive picture of dynamic aspects of biomolecular structure and function. The book will be of interest to graduate students and research workers in structural biochemistry (X-ray diffraction and NMR), theoretical chemistry (liquids and polymers), biophysics, enzymology, molecular biology, pharmaceutical chemistry, genetic engineering and biotechnology.
Structure and Dynamics of Nucleic Acids, Proteins, and Membranes
Title | Structure and Dynamics of Nucleic Acids, Proteins, and Membranes PDF eBook |
Author | E. Clementi |
Publisher | Springer Science & Business Media |
Pages | 454 |
Release | 2012-12-06 |
Genre | Science |
ISBN | 1468453084 |
This volume collects a number of the invited lectures and a few selected contrib utions presented at the International Symposium on Structure and Dynamics of Nucleic Acids, Proteins and Membranes held August 31st through September 5th, 1986, in Riva del Garda, Italy. The title of the conference as well as a number of the topics covered represent a continuation of two previous conferences, the first held in 1982 at the University of California in San Diego, and the second in 1984 in Rome at the Accademia dei Lincei. These two earlier conferences have been documented in Structure and Dynamics: Nucleic Acids and Proteins, edited by E. Clementi and R. H. Sarma, Adenine Press, New York, 1983, and Structure and Motion: Membranes, Nucleic Acids and Proteins, edited by E. Clementi, G. Corongiu, M. H. Sarma and R. H. Sarma, Adenine Press, New York, 1985. At this conference in Riva del Garda we were very hesitant to keep the name of the conference the same as the two previous ones. Indeed, a number of topics discussed in this conference were not included in the previous ones and even the emphasis of this gathering is only partly reflected in the conference title. An alternative title would have been Structure and Dynamics of Nucleic Acids, Proteins, and Higher Functions, or, possibly, "higher components" rather than "higher functions.
Dynamics of Proteins and Nucleic Acids
Title | Dynamics of Proteins and Nucleic Acids PDF eBook |
Author | |
Publisher | Elsevier |
Pages | 368 |
Release | 2013-08-14 |
Genre | Science |
ISBN | 0124116272 |
Published continuously since 1944, Advances in Protein Chemistry and Structural Biology has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. Covers reviews of methodology and research in all aspects of protein chemistry Brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics
Structure and Dynamics, Nucleic Acids and Proteins
Title | Structure and Dynamics, Nucleic Acids and Proteins PDF eBook |
Author | Enrico Clementi |
Publisher | |
Pages | 520 |
Release | 1983 |
Genre | Science |
ISBN |
Dynamics and the Problem of Recognition in Biological Macromolecules
Title | Dynamics and the Problem of Recognition in Biological Macromolecules PDF eBook |
Author | Oleg Jardetzky |
Publisher | Springer Science & Business Media |
Pages | 308 |
Release | 2012-12-06 |
Genre | Science |
ISBN | 1461558395 |
From within complex structures of organisms and cells down to the molecular level, biological processes all involve movement. Muscular fibers slide on each other to activate the muscle, as polymerases do along nucleic acids for replicating and transcribing the genetic material. Cells move and organize themselves into organs by recognizing each other through macromolecular surface-specific interactions. These recognition processes involve the mu tual adaptation of structures that rely on their flexibility. All sorts of conformational changes occur in proteins involved in through-membrane signal transmission, showing another aspect of the flexibility of these macromolecules. The movement and flexibility are inscribed in the polymeric nature of essential biological macromolecules such as proteins and nucleic acids. For instance, the well-defined structures formed by the long protein chain are held together by weak noncovalent interac tions that design a complex potential well in which the protein floats, permanently fluctuating between several micro- or macroconformations in a wide range of frequencies and ampli tudes. The inherent mobility of biomolecular edifices may be crucial to the adaptation of their structures to particular functions. Progress in methods for investigating macromolecular structures and dynamics make this hypothesis not only attractive but more and more testable.
Structure and Dynamics of Nucleic Acids and Proteins by NMR
Title | Structure and Dynamics of Nucleic Acids and Proteins by NMR PDF eBook |
Author | Marco Tonelli |
Publisher | |
Pages | 380 |
Release | 2003 |
Genre | |
ISBN |
Protein and Nucleic Acid Structure and Dynamics
Title | Protein and Nucleic Acid Structure and Dynamics PDF eBook |
Author | Jonathan King |
Publisher | Benjamin-Cummings Publishing Company |
Pages | 608 |
Release | 1985 |
Genre | Science |
ISBN |