Writing for general managers, the authors go beyond manufacturing structural decisions to actually changing the infrastructure of a manufacturing company--the leadership and vision, the policies and practices that are vital to creating superior factories and a dynamic learning continuum.

Engineering and design are often a necessary steps for an industry to become effective. Industry modeling can help to bridge the communication gap among engineers and system designers. Dynamic Methods and Process Advancements in Mechanical, Manufacturing, and Materials Engineering examines the principles of physics and materials science for analysis, design, manufacturing and maintenance of mechanical equipments and systems. Targeting researchers, practitioners, and academicians, this volume promotes innovative findings in mechanical, manufacturing and materials engineering.

A comprehensive look at existing technologies and processes for continuous manufacturing of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical industry has come under intense pressure to improve the efficiency of its manufacturing processes. Continuous process manufacturing provides a proven solution. Among its many benefits are: minimized waste, energy consumption, and raw material use; the accelerated introduction of new drugs; the use of smaller production facilities with lower building and capital costs; the ability to monitor drug quality on a continuous basis; and enhanced process reliability and flexibility. Continuous Manufacturing of Pharmaceuticals prepares professionals to take advantage of that exciting new approach to improving drug manufacturing efficiency. This book covers key aspects of the continuous manufacturing of pharmaceuticals. The first part provides an overview of key chemical engineering principles and the current regulatory environment. The second covers existing technologies for manufacturing both small-molecule-based products and protein/peptide products. The following section is devoted to process analytical tools for continuously operating manufacturing environments. The final two sections treat the integration of several individual parts of processing into fully operating continuous process systems and summarize state-of-art approaches for innovative new manufacturing principles. Brings together the essential know-how for anyone working in drug manufacturing, as well as chemical, food, and pharmaceutical scientists working on continuous processing Covers chemical engineering principles, regulatory aspects, primary and secondary manufacturing, process analytical technology and quality-by-design Contains contributions from researchers in leading pharmaceutical companies, the FDA, and academic institutions Offers an extremely well-informed look at the most promising future approaches to continuous manufacturing of innovative pharmaceutical products Timely, comprehensive, and authoritative, Continuous Manufacturing of Pharmaceuticals is an important professional resource for researchers in industry and academe working in the fields of pharmaceuticals development and manufacturing.

The past decade has seen considerable advances in CAE tools that employ leading-edge artificial intelligence techniques and that can be used with CAD/CAM tools to reduce design costs. In three parts, this book covers current Al applications that can prove beneficial in the design and planning stages of manufacturing, that can assist in solving scheduling and control problems, and that can be used in manufacturing integration.A. F. Famili is Research Scientist at the Knowledge Systems Laboratory of the National Research Council of Canada. Steven H. Kim is Visiting Fellow at the Design Research Institute, Cornell University. Dana S. Nau an Associate Professor in the Computer Science Department at the University of Maryland.Contents: Application of Machine Learning to Industrial Planning and Decision Making. Incorporating Special Purpose Resource Design in Planning to Make More Efficient Plans. Geometric Reasoning Using a Feature Algebra. Backward Assembly Planning Symmetry Groups in Solid Model-Based Assembly Planning. An Expert System Approach for Economic Evaluation of Machining Operation Planning. Interactive Problem Solving for Production Planning. An Abstraction-Based Search and Learning Approach for Effective Scheduling. ADDYMS: Architecture for Distributed Dynamic Manufacturing Scheduling. An Architecture for Real Time Distributed Scheduling. Teamwork Among Intelligent Agents: Framework and Case Study in Robotic Service. Exploiting Local Flexibility During Execution of Precomputed Schedules. Symbolic Representation and Planning for Robot Control Systems in Manufacturing. An Architecture for Integrating Enterprise Automation. An Intelligent Agent Framework for Enterprise Integration. Integrated Software System for Intelligent Manufacturing. Enterprise Management Network Architecture: A Tool for Manufacturing Enterprise Integration. Design and Manufacturing: Integration through Quality.

This book constitutes the refereed proceedings of the 12th International Conference on Subject-Oriented Business Process Management, S-BPM ONE 2020, held in Bremen, Germany, in December 2020. Due to the COVID-19 pandemic the conference was held online. The 10 full papers and 5 short papers were thoroughy reviewed and selected from 25 submissions. The volume also presents 1 keynote paper. The papers are thematically organized according to the following sections: subject-oriented business processing – syntax and semantics; cyber-physical and assistance systems; process mining and the Internet of actors and behaviors; Industry 4.0; various views on business process management.

This book covers the following main topics: A) information and knowledge management; B) organizational models and information systems; C) software and systems modeling; D) software systems, architectures, applications and tools; E) multimedia systems and applications; F) computer networks, mobility and pervasive systems; G) intelligent and decision support systems; H) big data analytics and applications; I) human–computer interaction; J) ethics, computers and security; K) health informatics; L) information technologies in education; M) information technologies in radio communications; N) technologies for biomedical applications. This book is composed by a selection of articles from The 2022 World Conference on Information Systems and Technologies (WorldCIST'22), held between April 12 and 14, in Budva, Montenegro. WorldCIST is a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences, and challenges of modern information systems and technologies research, together with their technological development and applications.