Can business change the world? Can the world change business? For a new breed of African social entrepreneurs, striving to build and grow enterprises that fight social ills, foster opportunity, and help to improve society, the answer is not can, it's must. Meet the Disruptors: impassioned by purpose, and emboldened by ideals, social entrepreneurs imagine a better way to a better world. And then they go out of their way to bring it to life. Through these tales of daring, struggle, triumph, and innovation, you'll learn their secrets as they blend business principles with social change. From healthcare to mobile gaming, from education to recycling, from dancing to gardening, these are the game-changers, the difference-makers, the doers of good. Here are their stories.

50 People Who Changed the World Includes stories of people such as: • Isaac Newton • Albert Einstein • Nikola Tesla • Marie Curie • Mohandas Gandhi • Steve Jobs • Jeff Bezos • Elon Musk • Madonna Meet 50 women and men who broke the rules and changed the world What does Charles Darwin have in common with Johannes Gutenberg—or with Jackson Pollock, Martin Luther, Betty Friedan, Steve Jobs, and DJ Kool Herc? They were the disruptors, upending established cultural, technical, spiritual, or scientific paradigms and altering the way we live forever. In The Disruptors, bestselling author Alan Axelrod presents dramatic and illuminating profiles, accompanied by original line drawings, of 50 visionaries who didn’t settle for the status quo. Their innovations range from the printing press (Gutenberg) to the fight for women’s equality (Friedan), from the iPhone (Jobs) to the innovation of hip-hop (Harc). They altered expectations about what constitutes art (Pollock), who controlled the way people worshiped (Luther), and where humanity came from (Darwin). Alan Axelrod is the author of more than 150 books. He has appeared in numerous magazine and newspaper articles as well as on many TV and radio programs.

The future will bring only more megatrends and disruptions. With the guidance of this book, which centers around the authors’ years-of-research-backed high-performance organizations (HPO) framework and includes the unique self-assessment tool Futurize! Diagnosis, business leaders and organizations will be prepared and truly ‘future ready.’ The next two decades will present massive challenges for organizations, as they navigate the need for sustainable development against a complex backdrop of factors such as increasing inequality, resource scarcity, continued globalization, and the ever-increasing speed of technological advancement. This book will help business leaders and organizations set priorities and make decisions so that not only do they honor commitments to the United Nations Sustainable Development Goals, but also become more future ready by: identifying the megatrends and disruptors which impact organizations now and will in the future specifically outlining how those megatrends and disruptors will impact organizations showing how organizations can deal with this impact in practical terms. This book is a must for management teams, aspiring leaders, and professionals and students interested in the future of work, human resource management, and innovation.

The rise of hard discounters like Aldi and Lidl has been monumental. Explore the very real threat they pose to traditional retailers and brand manufacturers and what you can learn from their growth. Hard discounters are stores that sell a limited selection of consumer-packaged goods and perishables - typically fewer than 2,000 Stock Keeping Units - for prices that are usually 50-60% lower than national brands. The best-known hard discounters are Aldi and Lidl, but global brands include Trader Joe's, EuroSpin, Biedronka, Netto and Leader Price. Their rise has been monumental; they have irrevocably changed the face of retail in Europe and Australia and are making steady inroads into the US. Retail Disruptors is the first book that explores this upheaval, providing expert insight into the business models of the leading hard discounters, and what mainstream retailers and brand manufacturers can do to remain competitive in the face of disruption. Meticulously researched by two of the leading authorities in retail strategy, private labels, branding, and hard discounting, Retail Disruptors is essential reading for all brand manufacturers and retailers who want to retain the competitive edge.

Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations

Our world and bodies are becoming increasingly polluted with chemicals capable of interfering with our hormones and thus, possibly, our present and future neural and mental health. As authors Heather Patisaul and Scott Belcher outline, there is a large lack of data and evidence in this causal relationship, which begs a need for further study to accelerate progress in the endocrinology and neuroendocrinology fields. Endocrine Disruptors, Brain, and Behavior focuses on if and how these chemicals, known as endocrine disrupting compounds (EDCs), affect the development and function of the brain and might be contributing to neural disorders rapidly rising in prevalence. The book provides an overall synthesis of the EDC field, including its historical roots, major hypotheses, key findings, and research gaps. The authors explain why even the concept of endocrine disruption is controversial in some circles, how differing definitions of endocrine disruption and what constitutes an "adverse" outcome on the brain shape public policy, and where the current capacity by different stakeholders (industry, academia, regulatory agencies) to evaluate chemicals for safety in a regulatory context begins and ends. The book concludes with suggestions for future research needs and a summary of emerging technology which might prove capable of more effectively evaluating existing and emerging chemicals for endocrine disrupting properties. As such, it provides the context for interdisciplinary and innovative input from a broad spectrum of fields, including those well-schooled in neuroscience, evolutionary biology, brain, behavior, sex differences, and neuroendocrinology.

The field of endocrine disruption or endocrine active compounds (EACs), which is just emerging and still controversial, is comprehensively covered by leading experts in Volume 3, Subvolumes L (Part I) and M (the present volume, Part II). The major classes of endocrine active chemicals are discussed, as well as methods for their detection and their association with health disturbances in humans and wildlife. The etiology of several of the human diseases associated with endocrine disruptors, e.g. breast and prostate cancer, decreased fertility and malformations, is still poorly understood, and the current state of knowledge is presented. Since hormonally active agents appear to have the potential of both adverse and beneficial effects, the evidence of health benefits associated with endocrine active compounds in humans is also presented. Basic chapters on the mode of action of EACs and on the etiology of the associated diseases facilitate the understanding of this complex subject for non-medical readers.