"Using the case of Uber, Disrupting D.C. examines how on-demand platforms more broadly are, and are not, remaking urban life"--

All too often, defining a discipline becomes more an exercise of exclusion than inclusion. Disrupting the Digital Humanities seeks to rethink how we map disciplinary terrain by directly confronting the gatekeeping impulse of many other so-called field-defining collections. What is most beautiful about the work of the Digital Humanities is exactly the fact that it can't be tidily anthologized. In fact, the desire to neatly define the Digital Humanities (to filter the DH-y from the DH) is a way of excluding the radically diverse work that actually constitutes the field. This collection, then, works to push and prod at the edges of the Digital Humanities - to open the Digital Humanities rather than close it down. Ultimately, it's exactly the fringes, the outliers, that make the Digital Humanities both lovely and rigorous. This collection does not constitute yet another reservoir for the new Digital Humanities canon. Rather, our aim is less about assembling content as it is about creating new conversations. Building a truly communal space for the digital humanities requires that we all approach that space with a commitment to: 1) creating open and non-hierarchical dialogues; 2) championing non-traditional work that might not otherwise be recognized through conventional scholarly channels; 3) amplifying marginalized voices; 4) advocating for students and learners; and 5) sharing generously to support the work of our peers. TABLE OF CONTENTS // Cathy N. Davidson, "Preface: Difference is Our Operating System" Dorothy Kim and Jesse Stommel, "Disrupting the Digital Humanities: An Introduction" I. Etymology Adeline Koh, "A Letter to the Humanities: DH Will Not Save You" Audrey Watters, "The Myth and the Millennialism of 'Disruptive Innovation'" Meg Worley, "The Rhetoric of Disruption: What are We Doing Here?" Jesse Stommel, "Public Digital Humanities" II. Identity Jonathan Hsy and Rick Godden, "Universal Design and Its Discontents" Angel Nieves, "DH as 'Disruptive Innovation' for Restorative Social Justice: Virtual Heritage and 3D Reconstructions of South Africa's Township Histories" Annemarie Perez, "Lowriding through the Digital Humanities" III. Jeremiad Mongrel Coalition Against Gringpo, "Gold Star for You," "Mongrel Dream Library" Michelle Moravec, "Exceptionalism in Digital Humanities: Community, Collaboration, and Consensus" Matt Thomas, "The Trouble with ProfHacker" Sean Michael Morris, "Digital Humanities and the Erosion of Inquiry" IV. Labor Moya Bailey, "#transform(ing)DH Writing and Research: An Autoethonography of Digital Humanities and Feminist Ethics" Kathi Inman Berens and Laura Sanders, "DH and Adjuncts: Putting the Human Back into the Humanities" Liana Silva Ford, "Not Seen, Not Heard" Spencer D. C. Keralis, "Disrupting Labor in Digital Humanities; or, The Classroom Is Not Your Crowd" V. Networks Maha Bali, "The Unbearable Whiteness of the Digital" Eunsong Kim, "The Politics of Visibility" Bonnie Stewart, "Academic Influence: The Sea of Change" VI. Play Edmond Y Chang, "Playing as Making" Kat Lecky, "Humanizing the Interface" Robin Wharton, "Bend Until It Breaks: Digital Humanities and Resistance" VII. Structure Chris Friend, "Outsiders, All: Connecting the Pasts and Futures of Digital Humanities and Composition" Lee Skallerup-Bessette, "W(h)ither DH? New Tensions, Directions, and Evolutions in the Digital Humanities" Chris Bourg, "The Library is Never Neutral" Fiona Barnett, "After the Digital Humanities, or, a Postscript" Conclusion Dorothy Kim, "#DecolonizeDH or A Practical Guide to Making DH Less White"

This Research Topic is a call for papers to provide an up to date assessment of current attempts to introduce tolerogenic therapies into clinical practice. Tolerance has been a highly sought after goal in the field of organ transplantation for over half a century, and is now readily achievable in rodent models, but considerable barriers remain to successfully translating tolerogenic treatments to the clinic. The initial call for this Research Topic has been aimed to provide an overview of recent advances made within the European RISET and American ITN networks with regard to tolerogenic strategies in clinical transplantation, autoimmune disease, and allergy. Articles will also cover the barriers to clinical tolerance induction and new emerging approaches to overcome such barriers. 1. Collaborative networks working towards the goal of therapeutic tolerance induction 2. Prope tolerance and minimization of immunosuppression 3. Lessons from operationally tolerant patients 4. Targeted withdrawal of immunosuppression 5. Stem cells and hematopoietic chimerism as a route to tolerance 6. Promoting regulatory T cells 7. Tolerogenic dendritic cells and negative vaccination 8. Inhibitory pathways and mechanisms in tolerance 9. Memory T cells and heterologous immunity 10. The innate response to allotransplants 11. Chronic graft loss--what are the missing links? 12. The impact of graft microenvironment on tolerance

Covering all the basic and clinical concepts you need to know for your coursework and USMLEs, Immunology, 9th Edition, offers a well-illustrated, carefully structured approach to this complex and fast-changing field. Carefully edited and authored by experts in both teaching and research, it provides cutting-edge, consistent coverage that links the laboratory and clinical practice. A user-friendly, color-coded format, including key concept boxes, explanatory diagrams, and nearly 200 photos to help you visually grasp and retain challenging concepts. Explains the building blocks of the immune system - cells, organs, and major receptor molecules - as well as initiation and actions of the immune response, especially in a clinical context. Includes extensive updates to clinical information, including recent clinical approaches in cancer immunology, transplantation, autoimmunity, hypersensitivity, and more. Features a reorganized format that presents immunology in the order in which is typically taught and learned, better integrating basic and clinical immunology. Covers new topics such as innate lymphoid cells, antibody-based therapies and antibody engineering, innate immunity and its components, the genetics of immunologically-based diseases and personalized medicine, and immunotherapeutic agents for the treatment of cancer. Provides Critical Thinking boxes, chapter-opening summaries, and case-based and USMLE-style questions that provide effective review and quick practice for exams – plus more learning opportunities online, including USMLE-style questions and clinical cases. Includes extensive updates to clinical information, including recent clinical approaches in cancer immunology, transplantation, autoimmunity, hypersensitivity, and more. Covers new topics such as innate lymphoid cells, antibody-based therapies and antibody engineering, innate immunity and its components, the genetics of immunologically-based diseases and personalized medicine, and immunotherapeutic agents for the treatment of cancer.

An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version

Digital technologies have changed how we shop, work, play, and communicate, reshaping our societies and economies. To understand digital capitalism, we need to grasp how advances in geospatial technologies underpin the construction, operation, and refinement of markets for digital goods and services. In The Map in the Machine, Luis F. Alvarez Leon examines these advances, from MapQuest and Google Maps to the rise of IP geolocation, ridesharing, and a new Earth Observation satellite ecosystem. He develops a geographical theory of digital capitalism centered on the processes of location, valuation, and marketization to provide a new vantage point from which to better understand, and intervene in, the dominant techno-economic paradigm of our time. By centering the spatiality of digital capitalism, Alvarez Leon shows how this system is the product not of seemingly intangible information clouds but rather of a vast array of technologies, practices, and infrastructures deeply rooted in place, mediated by geography, and open to contestation and change.