This book brings together some of the most influential pieces of research undertaken around the world in design synthesis. It is the first comprehensive work of this kind and covers all three aspects of research in design synthesis: - understanding what constitutes and influences synthesis; - the major approaches to synthesis; - the diverse range of tools that are created to support this crucial design task. With its range of tools and methods covered, it is an ideal introduction to design synthesis for those intending to research in this area as well as being a valuable source of ideas for educators and practitioners of engineering design.

In the early 1960s systematic techniques were introduced to guide engineers in producing high-quality designs. By the mid-1980s, these methods evolved from their informal guideline-like origins to more formal computable methods. Recently, highly automated design synthesis techniques have emerged. This timely work reviews the state of the art in formal design synthesis methods. It also provides an in-depth exploration of several representative projects in formal design synthesis and examines future directions in computational design synthesis research. The chapters are written by internationally renowned experts in engineering and architectural design.

This book brings together some of the most influential pieces of research undertaken around the world in design synthesis. It is the first comprehensive work of this kind and covers all three aspects of research in design synthesis: - understanding what constitutes and influences synthesis; - the major approaches to synthesis; - the diverse range of tools that are created to support this crucial design task. With its range of tools and methods covered, it is an ideal introduction to design synthesis for those intending to research in this area as well as being a valuable source of ideas for educators and practitioners of engineering design.

Sustainability in the Design, Synthesis and Analysis of Chemical Engineering Processes is an edited collection of contributions from leaders in their field. It takes a holistic view of sustainability in chemical and process engineering design, and incorporates economic analysis and human dimensions. Ruiz-Mercado and Cabezas have brought to this book their experience of researching sustainable process design and life cycle sustainability evaluation to assist with development in government, industry and academia. This book takes a practical, step-by-step approach to designing sustainable plants and processes by starting from chemical engineering fundamentals. This method enables readers to achieve new process design approaches with high influence and less complexity. It will also help to incorporate sustainability at the early stages of project life, and build up multiple systems level perspectives. Ruiz-Mercado and Cabezas’ book is the only book on the market that looks at process sustainability from a chemical engineering fundamentals perspective. Improve plants, processes and products with sustainability in mind; from conceptual design to life cycle assessment Avoid retro fitting costs by planning for sustainability concerns at the start of the design process Link sustainability to the chemical engineering fundamentals

The biggest challenge in any marketplace is uncertainty. The major changes taking place in world economies, politics, and demographics has raised market uncertainty to its highest level in the past 50 years. However, with new markets opening up in emerging and developing economies, the opportunities have never been better. To compete in this challe

The development of a new design is often thought of as a fundamentally human, creative act. However, emerging research has demonstrated that aspects of design synthesis can be formalized. First steps in this direction were taken in the early 1960s when systematic techniques were introduced to guide engineers in producing high-quality designs. By the mid-1980s these methods had evolved from their informal (guideline-like) origins to more formal (computable) methods. In recent years, highly automated design synthesis techniques have emerged. This intriguing book reviews formal design synthesis methods. It also provides an in-depth exploration of several representative projects in formal design synthesis and examines future directions in computational design synthesis research. Written by internationally renowned experts in engineering and architectural design, it covers essential topics in engineering design, and will appeal to designers, researchers and engineering graduate students.

Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations