Design, Development and Evaluation of an Oral Delivery System for Insulin
Title | Design, Development and Evaluation of an Oral Delivery System for Insulin PDF eBook |
Author | Mukur Gupta |
Publisher | |
Pages | 358 |
Release | 2004 |
Genre | Diabetes |
ISBN |
Oral Delivery of Insulin
Title | Oral Delivery of Insulin PDF eBook |
Author | T.A. Sonia |
Publisher | Elsevier |
Pages | 361 |
Release | 2014-12-11 |
Genre | Medical |
ISBN | 1908818689 |
Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. Presents an overview of Diabetes Mellitus Includes a discussion of various strategies and techniques adopted for oral delivery of insulin Presents an update of research in the field
Novel Formulation Approaches in the Design Strategy, Development and Evaluation of Oral Controlled Release Drug Delivery Systems
Title | Novel Formulation Approaches in the Design Strategy, Development and Evaluation of Oral Controlled Release Drug Delivery Systems PDF eBook |
Author | Viness Pillay |
Publisher | |
Pages | 750 |
Release | 2000 |
Genre | Drug delivery systems |
ISBN |
Formulation Development and Evaluation of Insulin-loaded Pluronic Gels for Buccal Drug Delivery
Title | Formulation Development and Evaluation of Insulin-loaded Pluronic Gels for Buccal Drug Delivery PDF eBook |
Author | Nilanjana Das |
Publisher | |
Pages | 342 |
Release | 2008 |
Genre | |
ISBN |
Oral Mucosal Drug Delivery and Therapy
Title | Oral Mucosal Drug Delivery and Therapy PDF eBook |
Author | Michael J. Rathbone |
Publisher | Springer |
Pages | 289 |
Release | 2015-03-13 |
Genre | Medical |
ISBN | 1489975586 |
This volume provides a comprehensive overview of the current issues facing scientists working on delivering drugs locally and systemically via the membranes that line the mouth. The book describes the anatomical and physiological challenges of this route for drug delivery and how they impact the design of oral mucosal drug delivery systems. It also provides a detailed description of current oral mucosal drug delivery technologies that overcome these challenges alongside research, development and assessment methods. In 11 authoritative chapters, the book affords an in-depth evaluation of the major issues associated with this route of administration, namely the retention of the drug/product at the site of administration and increasing drug permeability through the oral mucosa. The book provides insights into the in vitro and in vivo methods available to assess drug permeability and retention, offers solutions on how to improve the permeation of the drugs through the oral mucosa, and explores approaches to prolong drug/product retention at the site of administration. It also indicates future directions in research and product development. Oral Mucosal Drug Delivery and Therapy is a key resource for those wishing to extend their knowledge of this field.
Oral Delivery of Therapeutic Peptides and Proteins
Title | Oral Delivery of Therapeutic Peptides and Proteins PDF eBook |
Author | Puneet Tyagi |
Publisher | Academic Press |
Pages | 318 |
Release | 2022-08-18 |
Genre | Business & Economics |
ISBN | 0128210605 |
Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport. Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource. Demonstrates how proteins and peptides transport throughout the gastrointestinal tract and how to evaluate their biological fate when encapsulated into certain delivery systems Examines developing technologies to improve future oral bioavailability Includes the in vitro and preclinical techniques needed for development
Recent Advances in Novel Drug Carrier Systems
Title | Recent Advances in Novel Drug Carrier Systems PDF eBook |
Author | Ali Demir Sezer |
Publisher | BoD – Books on Demand |
Pages | 516 |
Release | 2012-10-31 |
Genre | Medical |
ISBN | 9535108107 |
This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.