Alzheimer's disease is a relentless affliction of the brain. It destroys memory, undermines personality, and ultimately causes or accelerates death. No specific or effective treatment has been found for this new and escalating degenerative social and economic scourge of the 20th Century.The pessimism extends to prevention... largely because the cause of Alzheimer's disease has not been clearly defined. It involves more than aging, heredity, or exposure to aluminum. Such pessimism is even more disturbing due to the fact that evidence of the disease can be found 20-30 years ( ) before memory problems develop.The result: relatives and other concerned individuals search in vain for rational advice about hygiene, diet and other prophylactic measures that are grounded on understandable insights about the nature of this disease. They include numerous neurotoxic advances associated with food processing, drugs, environmental chemicals, anesthesia, and even air travel.H.J. Roberts, M.D., condenses decades of careful observation and considerable personal research in this unprecedented original contribution. He clarifies the nature and evolution of Alzheimer's disease, including early warning signs. Dr. Roberts also places important issues in clearer perspective. For example, familial is not necessarily hereditary.With a minimum of medicalese, Dr. Roberts lists and concisely explains the most likely risk factors and clues for Alzheimer's disease. Even though many are common, most physicians do not consider them in this context. An example is chronic unexplained fatigue.Drawing upon this enormous body of observation and research, Dr. Roberts crystallizes a panoramic programof valid, albeit not guaranteed, preventive efforts before extensive and irreversible brain damage has occurred. These measures encompass nutrition, the avoidance or minimizing of exposure to neurotoxic influences, and wise suggestions about living in contemporary society.

Proudly presenting the widely anticipated new work of fiction from the multi-award winning bestselling author of Middlesex--a #1 major bestseller in Canada--and The Marriage Plot--also an acclaimed national bestseller--and the beloved The Virgin Suicides. Featuring unseen stories from one of the most eclectic, dynamic fiction writers working today, Fresh Complaint brings together works both new and previously published--including the crème de la crème of Eugenides's beloved New Yorker stories, never before collected between two covers. Jeffrey Eugenides's bestselling novels have shown that he is an astute observer of the crises of adolescence, sexual identity, self-discovery, family love and what it means to be an American in our times. The stories in Fresh Complaint continue that tradition. Ranging from the reproductive antics of "Baster" to the wry, moving account of a young traveller's search for enlightenment in "Air Mail" (selected by Annie Proulx for The Best American Short Stories 1997), this collection presents characters in the midst of personal and national crises. We meet a failed poet who, envious of other people's wealth during the real-estate bubble, becomes an embezzler; a clavichordist whose dreams of art collapse under the obligations of marriage and fatherhood; and, in "Bronze," a sexually confused college freshman whose encounter with a stranger on a train leads to a revelation about his past and his future. Narratively compelling, beautifully written and packed with a density of ideas that belie their fluid grace, Fresh Complaint proves Eugenides to be a master of the short form as well as the long. Showcasing stories from as far back as the 1980s and as recently as 2017, Fresh Complaint is the career-spanning collection from the Pulitzer Prize-winning author.

There are fewer grounds today than in the past to deplore a North‑South divide in research and innovation. This is one of the key findings of the UNESCO Science Report: towards 2030. A large number of countries are now incorporating science, technology and innovation in their national development agenda, in order to make their economies less reliant on raw materials and more rooted in knowledge. Most research and development (R&D) is taking place in high-income countries, but innovation of some kind is now occurring across the full spectrum of income levels according to the first survey of manufacturing companies in 65 countries conducted by the UNESCO Institute for Statistics and summarized in this report. For many lower-income countries, sustainable development has become an integral part of their national development plans for the next 10–20 years. Among higher-income countries, a firm commitment to sustainable development is often coupled with the desire to maintain competitiveness in global markets that are increasingly leaning towards ‘green’ technologies. The quest for clean energy and greater energy efficiency now figures among the research priorities of numerous countries. Written by more than 50 experts who are each covering the country or region from which they hail, the UNESCO Science Report: towards 2030 provides more country-level information than ever before. The trends and developments in science, technology and innovation policy and governance between 2009 and mid-2015 described here provide essential baseline information on the concerns and priorities of countries that could orient the implementation and drive the assessment of the 2030 Agenda for Sustainable Development in the years to come.

Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. An increasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke. Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemic stroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence is reviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing a practical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.

This book investigates the ways in which context shapes how cognitive challenges and strengths are navigated and how these actions impact the self-esteem of individuals with dementia and their conversational partners. The author examines both the language used and face maintenance in everyday social interaction through the lens of epistemic discourse analysis. In doing so, this work reveals how changes in cognition may impact the faces of these individuals, leading some to feel ashamed, anxious, or angry, others to feel patronized, infantilized, or overly dependent, and still others to feel threatened in both ways. It further examines how discursive choices made by healthy interactional partners can minimize or exacerbate these feelings. This path-breaking work will provide important insights for students and scholars of sociolinguistics, applied linguistics, medical anthropology, and health communication.

WINNER OF THE NAACP IMAGE AWARD WINNER OF THE CORETTA SCOTT KING AUTHOR AWARD National Book Award winner Jacqueline Woodson's stirring novel-in-verse explores how a family moves forward when their glory days have passed, and the cost of professional sports on Black bodies. Now in paperback. For as long as ZJ can remember, his dad has been everyone's hero. As a charming, talented pro football star, he's as beloved to the neighborhood kids he plays with as he is to his millions of adoring sports fans. But lately life at ZJ's house is anything but charming. His dad is having trouble remembering things and seems to be angry all the time. ZJ's mom explains it's because of all the head injuries his dad sustained during his career. ZJ can understand that--but it doesn't make the sting any less real when his own father forgets his name. As ZJ contemplates his new reality, he has to figure out how to hold on tight to family traditions and recollections of the glory days, all the while wondering what their past amounts to if his father can't remember it. And most importantly, can those happy feelings ever be reclaimed when they are all so busy aching for the past?

Alzheimer's disease is a degenerative brain disease which has major social consequences for the individuals affected and for those people who are emotionally and/or physically close to them. The role which language plays in such relationships stands at the centre of this book. In contrast to traditional analyses carried out by psycholinguists, neurologists and speech pathologists, with speech samples elicited in clinical settings, Heidi Hamilton examines language in the life of one elderly female Alzheimer's patient from an interactional sociolinguistic perspective. The language of open-ended, naturally occurring conversations between the patient and the author, over four-and-a-half years, is investigated in an attempt to understand how the patient's communicative abilities and disabilities are related and how they change over time, and, importantly, how they are influenced by pre-emptive and reactive communicative behaviours on the part of the patient's healthy interlocutor.