Collects Deadpool #40-44. After the fallout - nuclear and otherwise - of the Merc with a Mouth's antics in Arizona, the government is faced with an impossible question: what to do with Deadpool? The answer: stick him in an institution! When you think about it, it might be the only solution - after all, he really does need some professional help ... as well as protection from the enemy: himself.

Deadpool (2012) #20-25

The secrets of Deadpool revealed! In some of his funniest adventures of all time, the truth behind Deadpool's origins in the Weapon X program is explored, as well as his unique relationship with Death herself! Ajax returns for revenge on Dr. Killebrew as Deadpool faces the ghosts of his past...literally! And is Deadpool the Cosmic Messiah, destined to save all? Featuring Captain America, Batroc the Leaper, Blind Al and Arnim Zola! Collecting: Deadpool (1997) #18-25 & #0, Deadpool & Death Annual 1998

Collects Deadpool (2008) #50-63. Deadpool is desperate to end it all, but his healing factor makes dying a near-impossibility. When Wade finds the one thing in the world that can kill him - a serum that permanently disables his regenerative abilities - he just might get his wish. But his newfound ability to die makes Deadpool feel more alive than ever, and his sudden lust for life gets him in hot water with everyone he crosses - including crime bosses, super villains, his fellow mercenaries and even a dual-Beretta-wielding monkey! Can the Merc with a Mouth escape his pursuers and his pattern of insanity-fueled self-destruction, and finally live life to the fullest? Guest-starring the Uncanny X-Force, Daken, Kingpin, the Intelligencia and more - all of whom want to ensure that Deadpool finally meets his maker!

Collects Deadpool (2008) #19-22 & Hit-Monkey. Not many people - hero, villain, mercenary or otherwise - are going to upstage the Amazing Spider-Man in a team-up. But Deadpool will have to if he'll survive the most dangerous threat he's ever faced - Hit-Monkey! Plus: The origin of Hit-Monkey revealed!

Collects Spider-Man/Deadpool #19-22. Nobody does slapstick like Spidey and Deadpool do slapstick! Except, maybe Slapstick? But the walking cartoon has terrible comic timing, showing up exactly when the Merc with a Mouth and the webbed wonder have declared: no more jokes! But what could have driven them to take the funny out of their funny book? And with Slapstick’s animated antics to deal with, can the wall-crawler possibly keep his promise to take super-heroing more seriously? Then, when the villainous Arcade decides to build a new, deadlier Murderworld in Madripoor, he invites (by which we mean kidnaps) Spider-Man to be its first guest!

Collects Deadpool (2012) #1-14, #20 And #26. Comedy writing partners Brian Posehn and Gerry Duggan bring the funny, Deadpool-style, in one of the most celebrated eras of the Merc with a Mouth! Wade Wilson must take down an army of dead presidents — and things only get wilder from there! Deadpool is hired by a demon to reclaim damned souls; gets in touch with his feminine side; targets a man with aquatic powers; and teams up with the Superior Spider-Man! Plus: The debut of the flashback “inventory issue” tales Posehn and Duggan made famous, featuring Deadpool’s adventures in yesteryear! Deadpool drowns his sorrows with Iron Man, gets funky with Power Man and Iron Fist, wreaks Kirby-fied havoc on a cosmic level and fights Hitler alongside Cable and Nick Fury! Deadpool has never been more hilarious!