This book gathers 30 papers presented at the 21st PCBBE, which was hosted by the University of Zielona Góra, Poland, and offered a valuable forum for exchanging ideas and presenting the latest developments in all areas of biomedical engineering. Biocybernetics and biomedical engineering are currently considered one of the most promising ways to improve health care and, consequently, the quality of life. Innovative technical solutions can better meet physicians’ needs and stimulate the development of medical diagnostics and therapy. We are currently witnessing a profound change in the role of medicine, which is becoming ubiquitous in everyday life thanks to technological advances. Further, the development of civilization manifests itself in efforts to unlock the secrets of the human body, and to mimic biological systems in engineering. The biannual Polish Conference on Biocybernetics and Biomedical Engineering (PCBBE) has been held for nearly four decades and has attracted scientists and professionals in the fields of engineering, medicine, physics, and computer science. Gathering the outcomes of this conference, the book introduces the reader to recent developments and achievements in biocybernetics and biomedical engineering.

This book contains 13 chapters in which you can find various examples of the development of methods and/or systems supporting medical diagnostics and therapy, related to biomedical imaging, signal and image processing, biomechanics, biomaterials and artificial organs, modeling of biomedical systems, which, as the current research issues, were presented at the 22nd Polish BBE Conference held at the Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, in May 2021. Obviously, it is not easy to recommend an interdisciplinary book as it may seem inconsistent in some respects. This is the case here because it concerns the area of biocybernetics and biomedical engineering (BBE), which is not only an interdisciplinary but even multidisciplinary science. On the other hand, the scattered subject matter of the book is its advantage, as the book may be of interest to an advanced and wide range of readers and researchers representing both medical, biological and technical points of view.

This book presents the latest developments in the field of biomedical engineering and includes practical solutions and strictly scientific considerations. The development of new methods of treatment, advanced diagnostics or personalized rehabilitation requires close cooperation of experts from many fields, including, among others, medicine, biotechnology and finally biomedical engineering. The latter, combining many fields of science, such as computer science, materials science, biomechanics, electronics not only enables the development and production of modern medical equipment, but also participates in the development of new directions and methods of treatment. The presented monograph is a collection of scientific papers on the use of engineering methods in medicine. The topics of the work include both practical solutions and strictly scientific considerations expanding knowledge about the functioning of the human body. We believe that the presented works will have an impact on the development of the field of science, which is biomedical engineering, constituting a contribution to the discussion on the directions of development of cooperation between doctors, physiotherapists and engineers. We would also like to thank all the people who contributed to the creation of this monograph—both the authors of all the works and those involved in technical works.

This book constitutes the proceeding from IEEE EMBS International Student Conference (ISC) held online in Zabrze, 11-12th December, 2020. The conference was organized in cooperation between Students from Silesian University of Technology (Gliwice, Poland) and AGH University of Science and Technology (Kraków, Poland). The book consists of twenty full papers. Each submission included in this proceeding was subjected to a review process and accepted by the Conference Program Committee. IEEE Engineering in Medicine and Biology Society (EMBS) is the world’s largest international society of biomedical engineers. The organization’s 12,000 members reside in some 97 countries around the world. EMBS provides its members with access to the people, practices, information, ideas, and opinions that are shaping one of the fastest-growing fields in science. The International Student Conference is a special event organized by students for students. It creates an open environment for students, researchers, and scientists for presenting results of their recent work and learning about new trends in biomedical engineering. The conference is an opportunity to inspire students towards an academic career and encourage them to share their research experience.

This book gathers 30 papers presented at the 21st PCBBE, which was hosted by the University of Zielona Góra, Poland, and offered a valuable forum for exchanging ideas and presenting the latest developments in all areas of biomedical engineering. Biocybernetics and biomedical engineering are currently considered one of the most promising ways to improve health care and, consequently, the quality of life. Innovative technical solutions can better meet physicians' needs and stimulate the development of medical diagnostics and therapy. We are currently witnessing a profound change in the role of medicine, which is becoming ubiquitous in everyday life thanks to technological advances. Further, the development of civilization manifests itself in efforts to unlock the secrets of the human body, and to mimic biological systems in engineering. The biannual Polish Conference on Biocybernetics and Biomedical Engineering (PCBBE) has been held for nearly four decades and has attracted scientists and professionals in the fields of engineering, medicine, physics, and computer science. Gathering the outcomes of this conference, the book introduces the reader to recent developments and achievements in biocybernetics and biomedical engineering.

Medical Image Analysis presents practical knowledge on medical image computing and analysis as written by top educators and experts. This text is a modern, practical, self-contained reference that conveys a mix of fundamental methodological concepts within different medical domains. Sections cover core representations and properties of digital images and image enhancement techniques, advanced image computing methods (including segmentation, registration, motion and shape analysis), machine learning, how medical image computing (MIC) is used in clinical and medical research, and how to identify alternative strategies and employ software tools to solve typical problems in MIC. - An authoritative presentation of key concepts and methods from experts in the field - Sections clearly explaining key methodological principles within relevant medical applications - Self-contained chapters enable the text to be used on courses with differing structures - A representative selection of modern topics and techniques in medical image computing - Focus on medical image computing as an enabling technology to tackle unmet clinical needs - Presentation of traditional and machine learning approaches to medical image computing

In our rapidly aging society, tendon and ligament injuries pose a tremendous socioeconomic burden with a great impact on mobility and patient quality of life. Understanding tendon/ligament development and maturation, pathogenesis, wound healing, tissue engineering, and regenerative medicine approaches will be crucial. In this collection, we aim to showcase tendon and ligament research that spans the gamut of basic science to pre-clinical translation. These topics include but are not limited to tendon/ligament development and maturation, the pathogenesis of tendon and ligament injury, isolation and modification of stem cells and their products for regenerative medicine, identification and delivery of bioactive tenogenic/ligamentogenic molecules, development and characterization of bioactive and/or mechanically robust biomaterials in silico, in vitro, ex vivo, and in vivo for tissue engineering, as well as the use of novel multidisciplinary methodologies and technologies including systems biology and synthetic biology approaches for studying tendons and ligaments as well as enhancing their repair and regeneration. With this collection, we aim to expose readers to inter- and multi-disciplinary biological and bioengineering techniques and research, which will stimulate broader discussion and advance our understanding to improve tendon/ligament repair and regeneration.