An important review on transplantation for the general surgeon! Topics include: kidney transplant, left lobe liver transplants, advances in lung transplantation, stem cell and cellular transplants, pancreatectomy, management of organ failure, transplant immune suppression, antibody mediated rejection, cardiac assist devices, organ perfusion and preservation, weight reduction therapy, organ allocation and distribution, and more!

It is like a fairy story! Or at least a beautiful epic, a truly significant page in the history of medicine, a staggering scene in which several actors come into play, both fundamentalists and clinical practitioners, eager to place all these new developments at the disposal of those suffering from ill health. Everyone is passionate about their work, be it providing new knowledge or perfecting new therapeutic methods. Man has always been fascinated by the possibility of replacing a damaged organ with a healthy one. Several attempts have been made over the centuries, and some miracles have been reported, such as those of Saint Damien and Saint Come as illustrated by Fra Angelico. The modern saga, however, started more modestly on the mouse. It is on the mouse that the first tissue group was discovered; yet the study of human tissue groups could only be carried out on a human. One human must be subjected to the thousands of tests that have enabled us to unravel the extraordinary complexity of the HLA system.

Acute Care General Surgery provides a succinct focused overview of a myriad of general surgical emergencies. Each chapter has a concise, practical framework on the workup and management of a specific topic. The book covers a wide array of pathology from the more common appendicitis, diverticulitis and cholecystitis to those less frequently encountered such as toxic megacolon, Fournier's gangrene and volvulus. Learning objectives for each chapter are clearly defined. In addition to differential diagnosis, the work up and management is comprehensively discussed. In addition, a pithy clinical pearl is included to serve as a memory aid for each diagnosis. Upon reviewing this volume, clinicians who encounter the acute care surgical patient in their practices will be better equipped to rapidly assess, evaluate, diagnose and managing their complex and often challenging problems.

Aimed at the trainee surgeon and experienced transplant surgeon, this compendium on split-liver grafting contains articles written by faculty members of the first International Course on Split-Liver Transplantation. It covers the main aspects of the field and is geared towards helping surgeons select the best surgical techniques as well as identifying the pitfalls. The text features detailed instructions on the various procedures as well as an overview of the area.

Editor George Velmahos and authors highlight every important area in Acute Care Surgery for all general surgeons. Topics include obstruction, perforation, bleeding, acute inflammation, hernia emergencies, the open abdomen, necrotizing soft tissue infections, vascular emergencies, thoracic emergencies, and much more!

This issue of Surgical Clinics of North America focuses on Issues in Transplant Surgery, and is edited by Dr. Juan Palma-Vargas. Articles will include: Kidney transplantation: Patient selection, perioperative surgical issues and expected outcomes; Kidney paired donation; Management of abdominal surgical emergencies in transplant recipients: What a general surgeon should know; Post transplant malignancy; Liver transplantation: Patient selection, perioperative surgical issues and expected outcomes; Organ Preservation 101; Pediatric Abdominal Organ Transplantation; Pancreas Transplantation; Small Bowel Transplantation; Supply vs demand: Status of organ donation in the US, the wait list, and what can be done to close the gap; and more!

In this issue of Thoracic Surgery Clinics, guest editors Drs. Jasleen Kukreja and Aida Venado bring their considerable expertise to the topic of Lung Transplantation. Top experts in the field cover key topics such as inpatient management of the acutely decompensating lung transplant candidate, lung allograft rejection, management of the potential lung donor, postoperative management of lung transplant recipients, and more. - Contains a variety of relevant, practice-oriented topics including donation after circulatory death; lung transplant for ARDS; centralized organ recovery and reconditioning centers; infectious complications in lung transplantation; anesthetic management during lung transplantation; and more. - Provides in-depth clinical reviews on lung transplantation, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.