Praise for the Series: "Timely...High standard of Writing...It is to be highly recommended." --Quarterly Journal of Experimental Physiology This informative publication brings together knowledge of various aspects of cellular regulation. Current Topics in Cellular Regulation reviews the progress being made in those specialized areas of study that have undergone substantial development. It also publishes provocative new theories and concepts and serves as a forum for the discussion of general principles. Researchers in cellular regulation as well as biochemists, molecular and cell biologists, microbiologists, biophysicists, physiologists, nutritionists, and pathologists will find Current Topics in Cellular Regulation a useful source of up-to-date information. - CONTENTS: - Regulatory Features of Multicatalytic and 26S Proteases - Calponin - Type III Cyclic Nucelotide Phosphodiesterases and Insulin Action - Mammalian Aminoacyl-tRNA Synthetases - Regulation of Interaction between Signaling Protein CheY and Flagellar Motor during Bacterial Chemotaxis - The Chemical Biology of Nitric Oxide: Regulation and Protective and Toxic Mechanisms - Nutritional and Hormonal Regulation of Glutathione Homeostasis - Protein Folding and Association: In Vitro Studies for Self Organization and Targeting in the Cell

Current Topics in Cellular Regulation, Volume 16 considers the advances in the general area of cellular regulation. This book discusses the subcellular distribution of hexokinase in brain homogenates and experimental evidence for bound hexokinase as a compartmental control point. The enzymology and biologic significance of cytochrome c methylation, polyaromatic-biosynthetic multienzyme system, and proteolytic modulation of gene expression in sporulation are also elaborated. This text likewise covers the occurrence of cyclic nucleotide-synthesizing and -degrading enzymes in the mammalian brain and calcium ion as a positive effector of oocyte maturation. This volume is beneficial to biologists and researchers conducting work on the basic mechanisms involved in the regulation of diverse cellular activities.

Current Topics in Cellular Regulation: Volume 32 is a collection of papers that discusses the role of GTP-binding proteins in signal transduction, the activation of cholera toxin by ADP-ribosylation factors, and the signal transduction by the colony-stimulating factor-1 receptor. Other papers explain the secretory granule, the mechanism of stimulus-secretion coupling, calcium pumps in the plasma and intracellular membranes, as well as the protein phosphorylation in translational control. One paper proposes a linkage between the multimeric structures and cytoskeletal elements to bridge the signal transducing systems and the cytoskeletal network. Another paper describes the signaling mechanisms utilized by CSF-1R, the similarities, and differences when compared to other receptor tyrosine kinases (RTKs). The paper explains in detail the mechanism of ligand-induced kinase activation, and also the possible biological role of certain intracellular substrates. Another paper examines the role played by protein phosphorylation in the control of translation, or when possible, any additional regulatory mechanisms operating in other eukaryotic species. Biochemists, micro-biologists, bio-physicists, cellular researchers, and researchers involved in the study of cellular biology will find the collection very useful.

This informative publication brings together knowledge of various aspects of cellular regulation. Current Topics in Cellular Regulation reviews the progress being made in those specialized areas of study that have undergone substantial development. It also publishes provocative new theories and concepts and serves as a forum for the discussion of general principles.Researchers in cellular regulation as well as biochemists, molecular and cell biologists, microbiologists, and biophysicists will find Current Topics in Cellular Regulation a useful source of up-to-date information. This volume covers topics including cellular thiols and redox regulated signal transduction; integration of antagonistic signals in the regulation of nitrogen assimilation in E. coli; regulation of nuclear import and export and of glutathione synthesis, superoxide dismutase, oxidative stress, and cell metabolism; and thiol-based antioxidants.

Current Topics in Cellular Regulation.