Current Topics in Biochemistry 1973 is based on a series of lectures held at the National Institutes of Health dealing with biochemistry. This group of lectures is the most recent in a program, which was established in the mid-1960s, to review various research fields for the scientific community at the Institutes. The topics for these series were chosen to emphasize active fields of general interest for a diverse audience of scientists. The speakers were therefore encouraged to present an overview of their fields rather than a detailed discussion of current research problems. The lectures in present collection cover the following topics: the problem of predicting the conformation of a protein from a knowledge of its amino acid sequence; studies on the structure of glutamic dehydrogenase; immunologic approaches to the study of proteins; the NIH shift and its implications for the mechanism of biological oxidations; separation of transcribable and repressed chromatin; gene expression in animal cells; and plasma lipoproteins and apolipoproteins.

Current Topics in Membranes and Transport

Each issue lists papers published during the preceding year.

Current Topics in Experimental Endocrinology, Volume 2 covers major developments in the ever-expanding field of endocrinology. The book discusses the progress in cyclic nucleotide research; the hypothalamic control of the anterior pituitary hormone secretion-characterized hypothalamic hypophysiotropic peptides; and the pituitary-ovarian interrelationships in the rat. The text also describes the melatonin and the endocrine role of the pineal organ; the integration of the secretory control mechanisms for insulin, glucagon, and growth hormone; and the biological activity of somatomedin. The chemistry and physiology of parathyroid hormone, calcitonin, and vitamin d; and the physicochemical properties and activities of luteinizing hormone and human chorionic gonadotropin are also encompassed. Endocrinologists, physiologists, and students taking related courses will find the book invaluable.

This summary of rapid advances in the field of medical mycology is tailored to the needs of mycologists, physicians, and others using fungi as model systems.

First multi-year cumulation covers six years: 1965-70.

Current Topics in Cellular Regulation, Volume 14 reviews the advances in the general area of cellular regulation. This book discusses the mechanism and function of the C4 pathway, regulation of individual enzymes, inhibitors of isoleucine and valine biosynthesis, and patterns of derepression. The functions of 2,3-bisphosphoglycerate; 2,3-bisphosphoglycerate in erythrocytes during development; and regulation of glycogen synthetase activity are also elaborated. This publication likewise covers the substrate specificity of cAMP-dependent protein kinase, model systems of enzyme sequences, and posttranslational modifications in selected enzymes. This volume is a good source for biologists and researchers interested in the basic mechanisms involved in the regulation of diverse cellular activities.