In this issue of Medical Clinics of North America, guest editor Dr. Marie Krousel-Wood brings her considerable expertise to the topic of Current Challenges and New Directions in Preventive Medicine. Top experts in the field provide evidence-based recommendations and strategies for common preventative medicine topics, including screening and vaccinations. - Contains 13 relevant, practice-oriented topics including vaccine preventable diseases and vaccine hesitancy; substance use/opioid use disorder and clinical care; obesity-implementing evidence: strategies in clinical practice; healthcare providers and staff coping and burnout in the era of COVID-19; lifestyle medicine; and more. - Provides in-depth clinical reviews on preventive medicine, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Medical Clinics of North America, guest editors Drs. Geno Merli and Raghu Kolluri bring their considerable expertise to the topic of Vascular Medicine. Top experts in the field provide evidence-based recommendations on vascular issues and diseases for those in primary care, non-vascular medicine specialists, and nurse practitioners, including articles on atherosclerotic disease, peripheral artery disease, lower extremity vascular ulcers, vasculitis, vascular imaging for the primary care provider, and more. - Contains 12 practice-oriented topics including unprovoked venous thromboembolism: the search for a cause; approach to the patient with non-cardiac leg swelling; cold hands or feet: is it Raynaud's or not?; varicose veins: approaching assessment and management; and more. - Provides in-depth clinical reviews of vascular medicine, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Medical Clinics of North America, guest editors Drs. Anand V. Kulkarni and K. Rajender Reddy bring their considerable expertise to the topic of Hepatology: An Update. Top experts in the field cover key topics such as NAFLD; hepatic manifestations of a systemic illness; cirrhosis and portal hypertension; hepatic encephalopathy; ICU care of the patient with cirrhosis; hepatocellular carcinoma; liver transplantation for the non-hepatologist; and more. - Contains 15 relevant, practice-oriented topics including the global burden of chronic liver disease; the rising epidemic of alcoholic hepatitis; inpatient hepatology consultation; frailty and sarcopenia; and more. - Provides in-depth clinical reviews on hepatology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Medical Clinics of North America, guest editors Dr. Jeffrey Turner and Ursula Brewster bring their considerable expertise to the topic of An Update in Nephrology. Top experts in the field provide timely updates in CKD, kidney disease, kidney health, renal replacement therapy, and treatments. - Contains 12 practice-oriented topics including diagnosis of CKD and assessing eGFR; diabetic nephropathy; pregnancy in CKD: AKI in pregnant women and management of CKD in the pregnant patient; onco-nephrology; and more. - Provides in-depth clinical reviews on nephrology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Medical Clinics of North America, guest editor Dr. Susan Tuddenham brings her considerable expertise to the topic of Sexually Transmitted Infections. STIs are on the rise in the United States, and concerns for developing drug resistance and new and emerging infections may complicate management. In this issue, top experts in the field provide updates on some of the most important issues in STI diagnosis and management, highlighting new information and practical approaches relevant to primary care practice. - Contains 12 relevant, practice-oriented topics including taking a sexual history: best practices; herpes simplex virus: a practical guide to diagnosis, management, and patient counselling for the primary care clinician; update on monkeypox; sexual health and the transgender patient; and more. - Provides in-depth clinical reviews on sexually transmitted infections, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Medical Clinics of North America, guest editors Drs. Alexander Fanaroff and John W. Hirschfeld, Jr., bring their considerable expertise to the topic of Patient Management with Stable Ischemic Heart Disease. Top experts provide insights into newer diagnostic modalities for patients presenting with symptoms of stable ischemic heart disease, review the pillars of medical management as well as emerging cardiometabolic therapies, provide updates on the role of revascularization, and reveal gender, racial, ethnic, and socioeconomic disparities in the presentation and management of stable ischemic heart disease. - Contains 13 relevant, practice-oriented topics including optimal medical therapy for stable ischemic heart disease in 2024: focus on antithrombotic therapy; antiplatelet therapy for patients that have undergone revascularization within the past year: which agents and for how long; ischemic heart disease in women: focus on SCAD and MINOCA; and more. - Provides in-depth clinical reviews on patient management with stable ischemic heart disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Medical Clinics of North America, guest editors Drs. Heather Toth, Robert Kliegman, and Brett Bordini brings their considerable expertise to the topic of Adolescent Undiagnosed and Rare Diseases. Top experts address diagnostic dilemmas, disease mimics, unusual manifestations of common diseases, and rare disorders presenting as more common diseases in adolescents. - Contains 15 relevant, practice-oriented topics including syndromes with severe acne; common variable immunodeficiency (CVID); overlapping pain syndrome; late onset congenital hypoventilation syndrome (LOCH); adolescent onset of muscle weakness; and more. - Provides in-depth clinical reviews on adolescent undiagnosed and rare diseases, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.