"A book about theory and method in the humanities and social sciences. It reacts to what has become known as the "cultural turn," a shift toward semiotics, discourse, and representations and away from other sorts of determinations that started in the early 1980s and that has dominated social thinking for a long string of years. The book is based in a reconsideration of the meeting of two disciplines that helped to launch the cultural turn: anthropology and history. Specifically, it criticizes the ideas of hermeneutics and "thick description" (Clifford Geertz) that have come to play a key role in the encounter of anthropology and history and then in the cultural turn. It led to the renewed cherishing of what Gupta and Ferguson have called paradigms of "peoples and places," saturated pictures of universes, both small and large, of meaning ina more of less frozen standstill-an intellectual precursor to the cultural xenophobia of our times. Against this, the present book embraces praxis and "critical junctions": the connections in space (in and out of a relations of power and dependency, and what Eric Wolf has called the "interstitial relations" between apparently separate institutional domains. In this way the book adds to the current revival of institutionally based "global ethnography," which studies "up and outward" (the journal of Ethnography is a good example)."--Preface

There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells. The cellular structure is also crucial in drug therapies, namely, the permeability and bioavailability of the drugs, penetration of barriers such as the blood brain barrier. This current volume aims to summarise the current knowledge of tight junctions, their role in cancer and cancer metastasis and is of interest to scientists and clinicians.

This is the first of three volumes of the extensively revised and updated second edition of the Handbook of Superconductivity. The past twenty years have seen rapid progress in superconducting materials, which exhibit one of the most remarkable physical states of matter ever to be discovered. Superconductivity brings quantum mechanics to the scale of the everyday world where a single, coherent quantum state may extend over a distance of metres, or even kilometres, depending on the size of a coil or length of superconducting wire. Viable applications of superconductors rely fundamentally on an understanding of this intriguing phenomena and the availability of a range of materials with bespoke properties to meet practical needs. This first volume covers the fundamentals of superconductivity and the various classes of superconducting materials, which sets the context and background for Volumes 2 and 3. Key Features: Covers the depth and breadth of the field Includes contributions from leading academics and industry professionals across the world Provides hands-on guidance to the manufacturing and processing technologies A comprehensive reference, this handbook is suitable for both graduate students and practitioners in experimental physics, materials science and multiple engineering disciplines, including electronic and electrical, chemical, mechanical, metallurgy and others.

An accessible and comprehensive main text for courses on the presidency, this text argues that to be a successful presidential leader, one must effectively manage the enormous institutional and personal resources - or the "keys to power." Using the "keys to power" theme, Warshaw argues that the presidency is far more powerful today than in past generations. The book offers the most coverage in the market on the structures that provide the president with such power. As a result, there are discrete chapters dedicated to the vice president, the president's cabinet, the White House staff, and the executive office of the President. Standard topics such as "the president and the economy," are still covered but are integrated throughout the chapters.