This book aims to address a number of controversies concerning the use of testosterone treatment. It explains topics that clinicians regularly encounter such as whether to use free or total testosterone in the evaluation of the patient with testosterone deficiency; what factors actually impact testosterone levels, polycythemia, gynecomastia, bone density, and hyperprolactinemia in the testosterone deficient patient; critical analysis of the numerous questionnaires that are available to clinicians; and the impact of testosterone therapy on male fertility, cardiovascular disease, and prostate events including prostate cancer. Guiding the reader in both evaluation and management, the book also illuminates novel concepts in the T space such as testosterone use in the transgender population, T therapy as an endothelial modulator, bipolar testosterone therapy in the patient with advanced prostate cancer, and testosterone therapy as a performance enhancer. Controversies in Testosterone Deficiency is intended for any clinician involved in the care of patients with testosterone deficiency, exploring hot topics and correcting existent misinformation in the routine care of patients.

This book aims to address a number of controversies concerning the use of testosterone treatment. It explains topics that clinicians regularly encounter such as whether to use free or total testosterone in the evaluation of the patient with testosterone deficiency; what factors actually impact testosterone levels, polycythemia, gynecomastia, bone density, and hyperprolactinemia in the testosterone deficient patient; critical analysis of the numerous questionnaires that are available to clinicians; and the impact of testosterone therapy on male fertility, cardiovascular disease, and prostate events including prostate cancer. Guiding the reader in both evaluation and management, the book also illuminates novel concepts in the T space such as testosterone use in the transgender population, T therapy as an endothelial modulator, bipolar testosterone therapy in the patient with advanced prostate cancer, and testosterone therapy as a performance enhancer. Controversies in Testosterone Deficiency is intended for any clinician involved in the care of patients with testosterone deficiency, exploring hot topics and correcting existent misinformation in the routine care of patients.

Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies explores the difficulties around the diagnosis and treatment of androgen deficiency. The text examines the available evidence concerning the diagnosis and treatment of men with low testosterone. It also examines controversies in the identification and management of these men. While the information contained within will be of use to those who specialize in androgen deficiency and sexual medicine, the scope of the book will serve as a source of basic information about testosterone replacement and as a source of reasoned analysis of the controversies surrounding testosterone replacement in the aging male. Physicians and physician extenders will be able to apply evidence management principles to the evaluation and treatment of men with testosterone deficiency; supported by the most recent practice guidelines available. The authors represent a select group of physicians with expertise in androgen deficiency and replacement. Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies will be of great value to all physicians and physician extenders who deliver health care to men of all ages.

This book provides a background of essential knowledge on testosterone deficiency in men, including diagnosis and treatment. It also explores the associations of testosterone deficiency with organ systems and their diseases e.g diabetes, osteoporosis.

The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

This book provides a background of essential knowledge on testosterone deficiency in men, including diagnosis and treatment. It also explores the associations of testosterone deficiency with organ systems and their diseases e.g diabetes, osteoporosis.

This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.