The growing impact of nonlinear science on biology and medicine is fundamentally changing our view of living organisms and disease processes. This book introduces the application to biomedicine of a broad range of interdisciplinary concepts from nonlinear dynamics, such as self-organization, complexity, coherence, stochastic resonance, fractals and chaos. It comprises 18 chapters written by leading figures in the field and covers experimental and theoretical research, as well as the emerging technological possibilities such as nonlinear control techniques for treating pathological biodynamics, including heart arrhythmias and epilepsy. This book will attract the interest of professionals and students from a wide range of disciplines, including physicists, chemists, biologists, sensory physiologists and medical researchers such as cardiologists, neurologists and biomedical engineers.

The book summarizes the state-of-the-art of research on control of self-organizing nonlinear systems with contributions from leading international experts in the field. The first focus concerns recent methodological developments including control of networks and of noisy and time-delayed systems. As a second focus, the book features emerging concepts of application including control of quantum systems, soft condensed matter, and biological systems. Special topics reflecting the active research in the field are the analysis and control of chimera states in classical networks and in quantum systems, the mathematical treatment of multiscale systems, the control of colloidal and quantum transport, the control of epidemics and of neural network dynamics.

This book focuses on the research topics investigated during the three-year research project funded by the Italian Ministero dell'Istruzione, dell'Universit e della Ricerca (MIUR: Ministry of Education, University and Research) under the FIRB project RBNE01CW3M. With the aim of introducing newer perspectives of the research on complexity, the final results of the project are presented after a general introduction to the subject. The book is intended to provide researchers, PhD students, and people involved in research projects in companies with the basic fundamentals of complex systems and the advanced project results recently obtained.

Complex systems are usually difficult to design and control. There are several particular methods for coping with complexity, but there is no general approach to build complex systems. In this book I propose a methodology to aid engineers in the design and control of complex systems. This is based on the description of systems as self-organizing. Starting from the agent metaphor, the methodology proposes a conceptual framework and a series of steps to follow to find proper mechanisms that will promote elements to find solutions by actively interacting among themselves.

This book constitutes the refereed post-proceedings of the Third International Workshop on Engineering Self-Organising Applications, ESOA 2005, held in July 2005 as an associated event of AAMAS 2005. The 12 revised full papers and 6 revised short papers presented are organized in topical sections on novel self-organising mechanisms, methodologies, models and tools for self-organising applications, and specific applications of self-organising mechanisms.

This unique book offers a comprehensive and integrated introduction to the five fundamental elements of life and society: energy, information, feedback, adaptation, and self-organization. It is divided into two parts. Part I is concerned with energy (definition, history, energy types, energy sources, environmental impact); thermodynamics (laws, entropy definitions, energy, branches of thermodynamics, entropy interpretations, arrow of time); information (communication and transmission, modulation–demodulation, coding–decoding, information theory, information technology, information science, information systems); feedback control (history, classical methodologies, modern methodologies); adaptation (definition, mechanisms, measurement, complex adaptive systems, complexity, emergence); and self-organization (definitions/opinions, self-organized criticality, cybernetics, self-organization in complex adaptive systems, examples in nature). In turn, Part II studies the roles, impacts, and applications of the five above-mentioned elements in life and society, namely energy (biochemical energy pathways, energy flows through food chains, evolution of energy resources, energy and economy); information (information in biology, biocomputation, information technology in office automation, power generation/distribution, manufacturing, business, transportation), feedback (temperature, water, sugar and hydrogen ion regulation, autocatalysis, biological modeling, control of hard/technological and soft/managerial systems), adaptation and self-organization (ecosystems, climate change, stock market, knowledge management, man-made self-organized controllers, traffic lights control).

Introducton; Methology of knowledge representation; General inference principles; Hierarchical control systems; Expert control systems; Fuzzy control systems; Neurocontrol systems; Learning control systems; Intelligente control systems in application; Prospectives of intelligente control; References; Bibliography; Subject index.