Pneumonia is an inflammatory disease of the air sacs and surrounding interstitium caused by infectious agents or by endogenous inflammatory tissue disorder termed interstitial pneumonia. The present book covers contemporary topics of community, hospital, and health care-related bacterial and viral pneumonia in the setting of drug resistance, environmental exposures, climate change, hormonal influences, and gender. The topic of interstitial pneumonia is brought under the lens of an immune-related connective tissue disease.

Studying the lung microbiome requires a specialist approach to sampling, laboratory techniques and statistical analysis. This Monograph introduces the techniques used and discusses how respiratory sampling, 16S rRNA gene sequencing, metagenomics and the application of ecological theory can be used to examine the respiratory microbiome. It examines the different components of the respiratory microbiome: viruses and fungi in addition to the more frequently studied bacteria. It also considers a range of contexts from the paediatric microbiome and how this develops to disease of all ages including asthma and chronic obstructive pulmonary disease, chronic suppurative lung diseases, interstitial lung diseases, acquired pneumonias, transplantation, cancer and HIV, and the interaction of the respiratory microbiome and the environment.

This book offers an essential overview of aspiration pneumonia, and focuses on four major aspects: epidemiology, pathophysiology, new preventive strategies, and trending topics. Each part presents detailed findings and insights into critical issues for the treatment of the disease including its diagnosis, assessment, selecting antibiotics, similarities and differences between aspiration risk and aspiration pneumonia risk, different therapeutic approaches and so on. The book also discusses emerging topics concerning the definition of NHCAP and sleep apnea. Special attention is given to therapeutic and preventive approaches for the elderly, highlighting recent advances and the evidence on their positive outcomes. Since the patients with this disorder are often in a post-stroke state and elderly, the book is highly relevant for neurologists and geriatric physicians. Further, many surgeons also face this type of pneumonia in association with postoperative complications and cancer therapy related complications. Lastly, the definition of aspiration pneumonia and its therapeutic strategy have yet to be established in many countries, and the data presented here should serve as a guideline for its future diagnosis and treatment. As such, the book offers a valuable resource for primary physicians, pulmonologists, gerontologists, respiratory nurses, physical therapists, dentists and otolaryngologists alike.

Severe Community Acquired Pneumonia is a book in which chapters are authored and the same topics discussed by North American and European experts. This approach provides a unique opportunity to view the different perspectives and points of view on this subject. Severe CAP is a common clinical problem encountered in the ICU setting. This book reviews topics concerning the pathogenesis, diagnosis and management of SCAP. The discussions on the role of alcohol in severe CAP and adjunctive therapies are important topics that further our understanding of this severe respiratory infection.

Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.

Harrison's has defined internal medicine for millions of physicians and students worldwide since 1950. This Seventeenth Edition retains its balance of science and patient management and has been masssively updated to include an innovative array of new features and content. Beyond the expansion of an illustration program with more than 300 new, additional illustrations. The acclaimed "Approach to the Patient" and "Treatment" features have been redesigned to make referencing the content faster than ever before. Readers will find an expanded focus on global health, including a Global Advisory Board composed of 11 prominent medical experts from around the world and a chapter on Global Considerations in Medicine by Jim Kim and Paul Farmer. Also, the new chapter on the Epidemiology of Cardiovascular Diseases provides a uniquely valuable summary of this emerging global epidemic. A new Global Considerations icon identifies epidemiologic, diagnostic, and therapeutic distinctions betwe.