This book on current approaches to the use of drugs in dentistry aims to equip practitioners with a sound understanding of both the scientific evidence for various interventions and the comparative efficacy of those interventions. The focus is on the drugs most commonly used in conjunction with dental treatment, including local anesthetics, analgesics, antibiotics, sedatives, and drugs for the management of medical emergencies. Summaries of the scientific evidence from the available published literature are provided, with assessment of the level and quality of the evidence base. A unique aspect of the book is its focus on current, evidence-based recommendations from professional organizations with regard to special topics, such as antibiotic prophylaxis, pediatric considerations, and management of medically compromised patients. Emphasis is placed on evidence from randomized controlled trials, systematic reviews and meta-analyses, and in order to further enhance the up-to-date nature of the book, each chapter includes guidance on online resources, such as useful non-commercial websites .

A large number of diseases affect salivary gland (SG) secretion through different mechanisms, leading to SG dysfunction and associated oral problems. The glands may suffer from viral, bacterial, and, albeit rarely, fungal infections, which may cause painful swelling or obstruction; they could also become the target of an autoimmune attack or may be affected by various benign and malignant tumors which consist of a heterogeneous group of lesions with complex clinical–pathological characteristics. The loss of normal SG function results in widespread deterioration of oral health. This book, entitled “Diseases of Salivary Glands”, provides an overview of recent advances in the field of SG disorders, focusing on the cellular and molecular mechanisms involved in the pathogenesis of SG diseases and on the most innovative investigation techniques that could help to preserve patients’ health, function, and quality of life.

Anesthesia Outside of the Operating Room is a comprehensive, up-to-date textbook that covers all aspects of anesthesia care in OOR settings, from financial considerations to anesthetic techniques to quality assurance. With increasing numbers of procedures such as cardiac catheterization and imaging taking place outside of the main OR, anesthesia providers as well as non-anesthesia members of the patient care team will find this book critical to their understanding of the principles of anesthesia care in unique settings which may have limited physical resources. Topics include patient monitoring techniques, pre-procedure evaluation and post-procedure care, and procedural sedation performed by non-anesthesia providers. The authors address problems of anesthesia that have unique answers in OOR settings, such as patient transport and cardiac arrest, and discuss technological progress and considerations for the future. The text also covers surgical procedures and anesthetic considerations by procedure location, such as radiology, infertility clinics, field and military environments, and pediatric settings, among many others Select guidelines from the American Society of Anesthesiologists (ASA) are provided as well. Edited by the senior faculty from Harvard Medical School and with contributions from other academic institutions, Anesthesia Outside of the Operating Room provides a unique and convenient compendium of expertise and experience.

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

The first edition of this classic text appeared in 1976 with the aim of refining and standardising the advice given to the public and to ensure that such advice was scientifically sound and evidence-based. It was written not only for members of the dental professions and those involved in general healthcare including medical practitioners, school nurses, health visitors, midwives, dieticians, pharmacists and public health practitioners, but also those who influence health in the wider community, such as teachers, child carers and peer educators. While originally written for a UK readership it became clear that it was used in other countries and that a new international edition was needed. To ensure that this new edition would reflect a consensus of international expert opinion and be relevant to a much broader readership, a panel of eminent experts was enlisted from as far afield as Japan, Singapore, Denmark, Switzerland and the USA. The text is consistent with current evidence and guidance from the WHO, and includes comparative guidance from other countries and systematic reviews of research evidence from the Cochrane Collaboration database. It provides information and advice on the main aspects of oral health, including the cause and prevention of dental caries, periodontal disease, dental erosion, oral cancer and dental problems in children under five, and older people. Throughout the book, key points are given at the beginning of each chapter, with an indication of the strength of supporting scientific evidence using a simple scheme.

- NEW! Local Anesthesia for the Child and Adolescent chapter focuses on the delivery techniques and administration protocol needed for pediatric and adolescent patients. - NEW! Advanced local anesthetic techniques include the Vazirani-Akinosi mandibular block, intraseptal injections, and pre-puncture technique for the C-CLAD. - NEW! Coverage of dynamic and emerging topics include newer anesthetic agents, buffering of anesthetics, determination of drug dosages, armamentarium and syringe preparation, maxillary and mandibular injection techniques and fulcrums, and information on electronic devices and new equipment. - NEW clinical photos show basic and advanced injection techniques for maxillary and mandibular anesthesia, and new illustrations depict dental anatomy.