Design of biomedical products / G.J. Verkerke & E.B. van der Houwen -- Animal models in biomaterials research / G. Rakhorst ... [et al.] -- Technology assessment / J.M. Hummel -- Hemocompatibility of medical devices / W. van Oeveren -- Tissue and cell interactions with (bio)materials / T.G. van Kooten & R. Kuijer -- Biomaterials-associated surgery and infection / P.G.M. Maathuis ... [et al.] -- Cardiopulmonary bypass and postoperative organ dysfunction / Y.J. Gu -- Mechanical circulatory support systems / G. Rakhorst & M.E. Erasmus -- Biomaterials-related infections in orthopedic implants / D. Neut & R.L. Diercks -- Biomaterials for voice reconstruction / G.J. Verkerke ... [et al.] -- Biomaterials in ophthalmology / V.W. Renardel de Lavalette & S.A. Koopmans -- Biomaterials in plastic surgery / M.F. Meek -- Surgical meshes : morphology-dependent bacterial colonization / A.F. Engelsman

This book distinguishes between biomaterials for clinical use, and medical devices or components of devices. Biomaterials are defined as substances which can be placed in intimate contact with living structures without harmful effects. They become devices (internal or external to the body) when processed or shaped to serve a specific function. Implants are a subclass of devices which need to be located inside the body to achieve their purpose.

This book distinguishes between biomaterials for clinical use, and medical devices or components of devices. Biomaterials are defined as substances which can be placed in intimate contact with living structures without harmful effects. They become devices (internal or external to the body) when processed or shaped to serve a specific function. Implants are a subclass of devices which need to be located inside the body to achieve their purpose.

This useful book is written from a medical perspective and is aimed at academics as well as medical and biomedical engineering students who want to become involved in the design, development, manufacturing or use of prostheses or medical devices. It covers basic information on the complexities of implant and medical device development. The design process, technology assessment, animal experiments, histocompatibility, tissue compatibility and infections are described. In addition, examples of biomaterial applications are presented, showing the diversity of biomaterials.This is the first book that guides the reader through the complicated process of medical product development. Different technical and medical aspects of medical implants are highlighted by a group of authors who are actively involved in biomaterial research at the University Medical Center of Groningen, one of the leading hospitals in The Netherlands.

Biomedical Materials provides a comprehensive discussion of contemporary biomaterials research and development. Highlighting important topics associated with Engineering, Medicine and Surgery, this volume reaches a wide scope of professionals, researchers and graduate students involved with biomaterials. A pedagogical writing style and structure provides readers with an understanding of the fundamental concepts necessary to pursue research and industrial work on biomaterials, including characteristics of biomaterials, biological processes, biocompatibility, and applications of biomaterials in implants and medical instruments. Written by leading researchers in the field, this text book takes readers to the forefront of biomedical materials development, providing them with a taste of how the field is changing, while also serving as a useful reference to physicians and engineers.

Biomaterials for Skin Repair and Regeneration examines a range of materials and technologies used for regenerating or repairing skin. With a strong focus on biomaterials and scaffolds, the book also examines the testing and evaluation pathway for human clinical trials. Beginning by introducing the fundamentals on skin tissue, the book goes on to describe contemporary technology used in skin repair as well as currently available biomaterials suitable for skin tissue repair and regeneration. Skin tissue engineering and the ideal requirements to take into account when developing skin biomaterials are discussed, followed by information on the individual materials used for skin repair and regeneration. As evaluation of biomaterials in animal models is mandatory before proceeding into human clinical trials, the book also examines the different animal models available. With a strong focus on materials, engineering, and application, this book is a valuable resource for materials scientists, skin biologists, and bioengineers with an interest in tissue engineering, regeneration, and repair of skin. Provides an understanding of basic skin biology Comprehensively examines a variety of biomaterial approaches Looks at animal models for the evaluation of biomaterial-based skin constructs

New Functional Biomaterials for Medicine and Healthcare provides a concise summary of the latest developments in key types of biomaterials. The book begins with an overview of the use of biomaterials in contemporary healthcare and the process of developing novel biomaterials; the key issues and challenges associated with the design of complex implantable systems are also highlighted. The book then reviews the main materials used in functional biomaterials, particularly their properties and applications. Individual chapters focus on both natural and synthetic polymers, metallic biomaterials, and bio-inert and bioactive ceramics. Advances in processing technologies and our understanding of materials and their properties have made it possible for scientists and engineers to develop more sophisticated biomaterials with more targeted functionality. New Functional Biomaterials for Medicine and Healthcare provides an ideal one-volume summary of this important field that represents essential reading for scientists, engineers, and clinicians, and a useful reference text for undergraduate and postgraduate students. Provides a concise summary of the latest developments in key types of biomaterials Highlights key issues and challenges associated with the design of complex implantable systems Chapters focus on both natural and synthetic polymers, metallic biomaterials, and bio-inert and bioactive ceramics