Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and details recent advances in the modelling of the respiratory system for researchers, engineers, scientists, and health practitioners. It breaks down the complexities of this field and provides both students and scientists with an introduction and starting point to the physiology of the respiratory system, fluid dynamics and advanced CFD modeling tools. In addition to a brief introduction to the physics of the respiratory system and an overview of computational methods, the book contains best-practice guidelines for establishing high-quality computational models and simulations. Inspiration for new simulations can be gained through innovative case studies as well as hands-on practice using pre-made computational code. Last but not least, students and researchers are presented the latest biomedical research activities, and the computational visualizations will enhance their understanding of physiological functions of the respiratory system.

Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and details recent advances in the modelling of the respiratory system for researchers, engineers, scientists, and health practitioners. It breaks down the complexities of this field and provides both students and scientists with an introduction and starting point to the physiology of the respiratory system, fluid dynamics and advanced CFD modeling tools. In addition to a brief introduction to the physics of the respiratory system and an overview of computational methods, the book contains best-practice guidelines for establishing high-quality computational models and simulations. Inspiration for new simulations can be gained through innovative case studies as well as hands-on practice using pre-made computational code. Last but not least, students and researchers are presented the latest biomedical research activities, and the computational visualizations will enhance their understanding of physiological functions of the respiratory system.

Computational Fluid Dynamics: A Practical Approach, Fourth Edition is an introduction to computational fluid dynamics (CFD) fundamentals and commercial CFD software to solve engineering problems. The book is designed for a wide variety of engineering students new to CFD, but is also ideal for practicing engineers learning CFD for the first time. Combining an appropriate level of mathematical background, worked examples, computer screen shots, and step-by-step processes, this book walks the reader through modeling and computing, as well as interpreting CFD results. This new edition has been updated throughout, with new content and improved figures, examples and problems. - Updated throughout, with new case studies, examples, references, and corrections according to readers' and reviewers' feedback - Delivers the latest developments in CFD including the high-order and reduced-order modeling approach, machine learning–accelerated CFD, full coverage of high-speed fluid dynamics, and the meshless approaches to provide a broader overview of the application areas where CFD can be used - Reorganized and rewritten to better meet the needs of CFD instructors and students - Online resources include all lecturing and guest lecturing PPTs, computer lab practicing with step-by-step and screenshot guidelines, assignment and course project details, answers for review questions in each chapter, a new bonus chapter featuring detailed case studies, and result discussion

Inhalation aerosols continue to be the basis for successful lung therapy for several diseases, with therapeutic strategies and the range of technology significantly evolving in recent years. In response, this third edition takes a new approach to reflect the close integration of technology with its application. After briefly presenting the general considerations that apply to aerosol inhalation, the central section of the book uses the focus on disease and therapeutic agents to illustrate the application of specific technologies. The final integrated strategies section draws the major points from the applications for disease targets and drug products.

Toxicological Evaluation of Electronic Nicotine Delivery Products (ENDP) discusses the scientific basis for the toxicological assessment and evaluation of ENDPs. The book covers aerosol chemistry, in vitro and in vivo studies as well as clinical studies. It provides the basis for the evaluation of short and long term-effects, along with relative risks. It also examines the potential role of ENDPs in tobacco harm reduction and how they may reduce the risk of disease in smokers who switch to them. This book is a comprehensive resource for toxicologists, health practitioners and public health professionals who want the scientific information necessary to assess the relative risk of ENDPs when compared with cigarette smoking and cessation. - Delivers a comprehensive overview of current state of science - Offers an integrated analysis of e-cigarettes and heated tobacco products - Provides guidance for methodologies

The Multiphase Flow Handbook, Second Edition is a thoroughly updated and reorganized revision of the late Clayton Crowe’s work, and provides a detailed look at the basic concepts and the wide range of applications in this important area of thermal/fluids engineering. Revised by the new editors, Efstathios E. (Stathis) Michaelides and John D. Schwarzkopf, the new Second Edition begins with two chapters covering fundamental concepts and methods that pertain to all the types and applications of multiphase flow. The remaining chapters cover the applications and engineering systems that are relevant to all the types of multiphase flow and heat transfer. The twenty-one chapters and several sections of the book include the basic science as well as the contemporary engineering and technological applications of multiphase flow in a comprehensive way that is easy to follow and be understood. The editors created a common set of nomenclature that is used throughout the book, allowing readers to easily compare fundamental theory with currently developing concepts and applications. With contributed chapters from sixty-two leading experts around the world, the Multiphase Flow Handbook, Second Edition is an essential reference for all researchers, academics and engineers working with complex thermal and fluid systems.

This book aims to predict and model the transport of bioaerosols, identify their transmission characteristics, and assess occupants’ infection risks. Although existing epidemiological books provide fundamental infection rate of existing diseases, the ability of predicting emerging disease transmission in the air and assessing occupants’ infection risks to the bioaerosols is significantly lacking. This book is considered as a professional book that provides in-depth discussion of the aforementioned issues and provides potential approaches to solve these issues would be highly demanded by readers in this emerging research field. This book offers essential and systematic analysis on the fate of bioaerosols from their release in the air to the final destination in human’s respiratory systems through direct 3D visualizations techniques. It also provides quantifiable method to assess each occupant’s infection risks to the infectious bioaerosols in indoor environments. The readers will gain essential fundamental characteristics of bioaerosols (active time, viability, etc.) and will gain the advanced skills on how to integrate these properties into numerical modeling and assess the occupants’ exposure risks.