This publication is intended to contribute to prevention and control of the morbidity and mortality associated with dengue and to serve as an authoritative reference source for health workers and researchers. These guidelines are not intended to replace national guidelines but to assist in the development of national or regional guidelines. They are expected to remain valid for five years (until 2014), although developments in research could change their validity.--Publisher's description.

Dengue Fever is the fastest emerging arboviral infection with major public health consequences for millions of people around the world, and in particular the South-East Asia region. These regional guidelines were extensively revised, updated and expanded with the focus on new and additional topics of current relevance to the populations of the region. They are intended to provide guidance to national and local-level program managers and public health officials, as well as stakeholders, including health practitioners, laboratory personnel and multisectoral partners, in strategic planning, implementation, monitoring and evaluation, and strengthening the response to dengue prevention and control in their countries. Scientists and researchers involved in vaccine and antiviral drug development will also find crucial baseline information in this publication.

A comprehensive guide to the diagnosis, clinical management, epidemiological, surveillance, prevention and control of dengue and dengue haemorrhagic fever. Although guidelines and advice are universally relevant, the manual is specifically designed for use in South-East Asian countries, where dengue fever remains a major public health concern. Recommendations and advice respond to research demonstrating that different geographic areas show a variable response to infection, have different epidemiological patterns, and require different approaches to control. The book also responds to past failures to control dengue in these countries, citing almost exclusive concentration on space spraying of adult mosquitoes as one of the most important causes. With these problems in mind, the book places major emphasis on measures that can make communities responsible for vector control in the domestic environment as the best way to secure sustained improvements in prevention and control. The book has twelve chapters. The first summarizes what is known about the virus, vector, host, transmission cycle, and virus-host interactions. A brief overview of the global situation is followed by a detailed chronology of the resurgence of dengue in South-East Asia. Clinical manifestations and diagnosis are covered in chapter two, which includes precise criteria for reaching a diagnosis based on clinical manifestations and laboratory findings. Chapter three, on clinical management, gives particular attention to the management of dengue shock syndrome as a medical emergency. The important role of laboratory diagnosis is addressed in chapter four, which describes in detail the laboratory confirmatory tests that are essential for diagnosis. A chapter offering advice on the epidemiological surveillance of cases and vectors is followed by a brief description of vector distribution and bioecology. The second half of the book is devoted to strategies for prevention and control, emphasizing vector control measures that can be undertaken by communities as the best approach to successful and sustainable control. Detailed advice, supported by line drawings, checklists, and charts, is given for all appropriate environmental, biological, and chemical methods of vector control. The book also includes a chapter explaining how to develop an emergency plan for rapid response to epidemics. Further practical guidance is provided in a series of fifteen annexes, which include a model arbovirus laboratory request form, a guide to the relative sensitivity and interpretation of serological tests, and abundant advice on environmental and chemical methods of vector control specific to South-East Asia.

Continued geographic expansion of dengue viruses and their mosquito vectors has seen the magnitude and frequency of epidemic dengue/dengue hemorrhagic fever (DF/DHF) increase dramatically. Recent exciting research on dengue has resulted in major advances in our understanding of all aspects of the biology of these viruses, and this updated second edition brings together leading research and clinical scientists to review dengue virus biology, epidemiology, entomology, therapeutics, vaccinology and clinical management.

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

The main objective of these guidelines is to provide practical information on the steps for preventing and controlling outbreaks of dengue hemorrhagic fever. The main emphasis is on vector surveillance and control, and priority is given to simple environmental measures which individuals and communities can take to eliminate larval breeding. The strategy used to control adult Aedes mosquitos before and during outbreaks is given within the framework of a comprehensive, controlled approach, which includes personal protection measures, space spraying, legislation and the early recognition and treatment of dengue hemorrhagic fever cases. These guidelines should be a valuable source of information for those engaged in controlling dengue hemorrhagic fever.