While reflux disease, achalasia, esophageal spasm, gastroparesis and IBS include some of the most common disorders in all disease categories, the understanding of their pathophysiology has remained elusive. The field of clinical gastrointestinal motility has for decades relied on the measurement of intestinal movements for diagnosis and management of these difficult and enigmatic disorders of gut function. Although computers have increased the speed with which we can measure the movements of the gut, the devices to measure this movement have not changed in over 20 years. In the last 2 years, a new technologic breakthrough has taken place in the measurement of intestinal movement. The technology is called high resolution manometry. Rather than the old 4 and 8 channels systems of measuring pressure, high resolution employs 36 closely spaced solid state pressure transducers. By using this technology, the resolution of gut motor activity is incredible. This allows for better ways of viewing motility using color as pressure. This technology makes for beautiful images of gut motility that we have never seen before. We have made diagnoses that would never have been appreciated with the old technology. High resolution manometry is taking over conventional manometry worldwide and represents a dramatic leap in a long time stagnant area.

This atlas provides a concise yet comprehensive overview of high-resolution manometry, impedance and pH monitoring. Through instructive text and over 130 high-yield images, the atlas describes the basic principles of esophageal, antroduodenal and anorectal high-resolution manometry, reviews both normal and pathologic findings on manometry, covers technical aspects of pH monitoring and impedance, and outlines advances in equipment, software, and diagnostic guidelines. Written by experts in the field, Atlas of High-Resolution Manometry, Impedance, and pH Monitoring is a valuable resource for gastroenterologists and other clinicians and practitioners who work or are interested in the GI motility field.

The book provides a comprehensive overview of high resolution and high definition anorectal manometry (HRAM/HDAM), showing the possible benefits of a wider use of these techniques in clinical practice, as well as their limitations. Although these techniques provide fresh insights into anorectal function and offer a new perspective on the pathophysiologic mechanisms of many defecation disturbances, there is a need to clarify whether their use has beneficial effects on clinical management compared to conventional manometry. There is still a considerable way to go to gain the clinical diffusion of esophageal HRM, which has become the gold standard in studying esophageal motility. Indeed, many gastroenterologists and surgeons are convinced that further studies are necessary in order to be able to recommend HRAM and HDAM over and above conventional anorectal manometry. The first part of the book presents anorectal anatomy and pathophysiology, highlighting the indications and limitations of conventional anorectal manometry. The second part then focuses on the general concepts of high resolution manometry and the difference between conventional anorectal manometry and HRAM/HDAM, including technical aspects and different equipment. The third part explains how to perform, analyze and interpret HRAM and HDAM recordings, and describes the parameters study protocol, normal values and how to formulate a particular diagnosis. Lastly, the fourth part includes a collection of normal and pathological images with a glossary of the most frequently terms. Written by experts in the field of anorectal manometry and defecation disorders, this book is of interest to specialists and residents dealing with these conditions.

Clinical and Basic Neurogastroenterology and Motility is a state-of-the-art, lucidly written, generously illustrated, landmark publication that comprehensively addresses the underlying mechanisms and management of common adult and pediatric motility disorders. These problems affect 50% of the population and include conditions such as dysphagia, achalasia, gastroesophageal reflux disease, gastroparesis, irritable bowel syndrome (IBS), gas and bloating, SIBO, constipation and fecal incontinence. The book brings together international experts and clinician scientists, epitomizing their years of wisdom into a concise yet practical text that is delivered in two distinct sections, basic and clinical. It fulfills a large unmet need, and bridges a long-awaited knowledge gap among trainees, clinicians, scientists, nurses and technicians, earnestly engaged in this field. - First of its kind text that covers both basic and clinical aspects, bridging the knowledge gap, and providing a bench to bedside approach for management of common disorders - Discusses the latest concepts and basic principles of neurogastroenterology and motility, and how the gut and brain interact in the genesis of functional gastrointestinal and motility disorders - Provides an illustrated and practical text on hot topics written by leading adult and pediatric gastroenterology experts across the globe - Includes an accompanying more detailed web version of the text with free access to future podcasts

Now in its 10th edition, Sleisenger and Fordtran?s Gastrointestinal and Liver Disease remains your indispensable source for definitive, state-of-the-art answers on every aspect of gastroenterology and hepatology. Overcome your most complex clinical challenges and make optimal use of the newest techniques, technologies, and treatments?with superb guidance from hundreds of world-renowned authorities. Meticulous updates throughout include the latest approaches and improvements in gastrointestinal and liver disease diagnosis and therapy as well as hundreds of images and 35 new procedural videos. "..one of the most valuable clinical resources in the dynamic field of gastroenterology and hepatology." Reviewed by Brindusa Diaconu on behalf of the Journal of Gastrointestinal and Liver Diseases, July 2015 "..an engaging, educational yet clinically orientated textbook which is relevant to modern clinical practice." Reviewed by Dr Harry Brown on behalf of glycosmedia.com, April 2015 "I can personally attest to the remarkable advances that have been made, as I was author of the chapter on eosinophilic gastroenteritis in the second edition of the textbook, and reading the same chapter in the tenth edition underscores the important advances that have been made in our understanding of the molecular basis as well as the pathophysiology of this and related disorders." Foreword by Norton J. Greenberger, MD Boston, Massachusetts, June 2015 Consult this title on your favorite e-reader. Get the essential gastroenterology information you need from one authoritative source with an outstanding global reputation for excellence. Zero in on the key information you need to know with a consistent, full-color chapter design. Stay up to date with emerging and challenging topics: enteric microbiota and probiotics; fecal microbiota transplantation; Clostridium difficile colitis; and factitious gastrointestinal diseases. Incorporate the latest findings and improvements in care for liver disease patients—from diagnosis and treatment through post-treatment strategies and management of complications. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.