This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.

A practical guide to laboratory diagnosis and treatment of hemostatic disorders. This concise book covers all you need to know to manage thrombotic and bleeding disorders, distilling the most clinically up-to-date information, and including the latest treatment strategies for key conditions and diseases. Essential Guide to Blood Coagulation covers both the stable and the acute stages of hereditary and acquired bleeding and thrombotic disorders. Faced with a bleeding patient, it may be difficult to determine whether blood loss is due to a local factor or an underlying hemostatic defect. There are a range of laboratory tests which can be performed to identify the cause of bleeding in a patient. This book highlights the tests that can be used in the laboratory to aid diagnosis. Originally published in Swedish, Essential Guide to Blood Coagulation, has been revised to include the latest treatment strategies available for patients and will help clinicians to expand their knowledge of hemostatic disorders.

A Doody's Core Title 2012 Each day pathologists are faced with ordering laboratory tests with which they are unfamiliar. An incorrectly ordered test or error in interpreting test results can lead to mistakes that compromise patient safety. Coagulation Disorders is designed to show clinical pathologists, lab managers, medical technologists, and residents how to avoid common errors in test selection and result interpretation in diagnostic coagulation. Utilizing a case-based approach, each chapter features a concise overview of a major diagnosis, with multiple illustrative cases, and then a list of recommended standards of care pertinent to the problem. Just as it is essential for the practitioner in the diagnosis of bleeding and thrombotic disorders to know the appropriate course of action to establish a diagnosis or to appropriately treat a patient, it is equally essential to also know what not to do. Avoiding the mistakes is a critical first step to optimizing patient outcome and maximizing patient safety. Features of Coagulation Disorders include: An emphasis on identifying established, evidence-based standards in coagulation testing Actual case illustrations of commonly seen errors as well as the result of those errors on patient outcome and laboratory management Examples of errors which compromise patient safety across all major areas of laboratory medicine Pocket-sized for portability About the Series A key issue for every laboratory and individual laboratory practitioner is the assessment of risk and a current working knowledge of the standards of care established for diagnostic testing via guidelines, major studies and trials. The Diagnostic Standards of Care series presents common errors associated with diagnoses in clinical pathology, using case examples to illustrate effective analysis based on current evidence and standards. In addition to being practical diagnostic guides, each volume demonstrates the use of quality assurance and the role of the pathologist in ensuring quality and patient safety.

The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.

This clinical casebook provides a concise, state-of-the-art review of pediatric bleeding disorders. Presented in a case-based format, each case presents a different variant of bleeding disorder, illustrates the etiology, pathology, genetics, diagnosis, and management of the disorder, and offers clinical pearls. Disorders covered include hemophilia A and B, rare factor deficiencies, von Willebrand disease, immune thrombocytopenia purpura, and platelet dysfunctions. Written by experts in the field, Pediatric Bleeding Disorders: A Clinical Casebook is a valuable resource for clinicians and practitioners treating patients with challenging coagulation issues.

Highly Commended - 2010 BMA Medical Book Awards An essential, practical manual for all those working in transfusion medicine Concise and user-friendly guide to transfusion medicine Focuses on clinical aspects but also covers background science and organizational issues Complications encountered in transfusion are addressed throughout Highlights controversial issues and provides advice for everyday clinical questions in transfusion medicine This comprehensive guide to transfusion medicine takes a practical and didactic approach. The third edition of this text includes many new contributions and has expanded to seven sections. The first of these takes the reader systematically through the principles of transfusion medicine. The second deals with the complications which can arise in transfusion and is followed by a section on the practice of transfusion in blood centres and hospitals. The fourth section covers clinical transfusion practice and the fifth looks at alternatives to transfusion. Section six addresses cellular and tissue therapy and organ transplantation and the final section of the book examines the development of the evidence base for transfusion. As with previous editions; the final section includes a visionary chapter on future advances in the field. This new edition of Practical Transfusion Medicine benefits from even more international authorship than the previous two editions and is an invaluable resource for trainee doctors, scientists, technicians and other staff in haematology and transfusion and as a reference book for clinical staff in haematology and other disciplines faced with specific problems.

This book aims to provide condensed and crystallised knowledge, providing the rationale for investigations and interventions. Emergency medicine is a specialty where time and knowledge are critical factors in deciding appropriate management which could otherwise result in loss of life or limb. The challenge often is to have lucid management plans, whilst standing at the bedside of the patient. In order to address this challenge, a manuscript is needed which aims to enhance the clinical skills of the emergency physician. The objective of this book is to compile a road map for practitioners of emergency medicine, which would guide them through algorithm-based pathways. This format is distinctive by nature for its concise presentation, which facilitates easy reading and early application. Written by global experts, this book aims to be a truly international representation of emergency physicians who have come together to deliver contemporary concepts in emergency patient care.