Advances in experimental methods have resulted in the generation of enormous volumes of data across the life sciences. Hence clustering and classification techniques that were once predominantly the domain of ecologists are now being used more widely. This 2006 book provides an overview of these important data analysis methods, from long-established statistical methods to more recent machine learning techniques. It aims to provide a framework that will enable the reader to recognise the assumptions and constraints that are implicit in all such techniques. Important generic issues are discussed first and then the major families of algorithms are described. Throughout the focus is on explanation and understanding and readers are directed to other resources that provide additional mathematical rigour when it is required. Examples taken from across the whole of biology, including bioinformatics, are provided throughout the book to illustrate the key concepts and each technique's potential.

Research Methods for the Biosciences is the perfect resource for students wishing to develop the crucial skills needed for designing, carrying out, and reporting research, with examples throughout the text drawn from real undergraduate projects.

Praise for the First Edition “...a well-written book on data analysis and data mining that provides an excellent foundation...” —CHOICE “This is a must-read book for learning practical statistics and data analysis...” —Computing Reviews.com A proven go-to guide for data analysis, Making Sense of Data I: A Practical Guide to Exploratory Data Analysis and Data Mining, Second Edition focuses on basic data analysis approaches that are necessary to make timely and accurate decisions in a diverse range of projects. Based on the authors’ practical experience in implementing data analysis and data mining, the new edition provides clear explanations that guide readers from almost every field of study. In order to facilitate the needed steps when handling a data analysis or data mining project, a step-by-step approach aids professionals in carefully analyzing data and implementing results, leading to the development of smarter business decisions. The tools to summarize and interpret data in order to master data analysis are integrated throughout, and the Second Edition also features: Updated exercises for both manual and computer-aided implementation with accompanying worked examples New appendices with coverage on the freely available TraceisTM software, including tutorials using data from a variety of disciplines such as the social sciences, engineering, and finance New topical coverage on multiple linear regression and logistic regression to provide a range of widely used and transparent approaches Additional real-world examples of data preparation to establish a practical background for making decisions from data Making Sense of Data I: A Practical Guide to Exploratory Data Analysis and Data Mining, Second Edition is an excellent reference for researchers and professionals who need to achieve effective decision making from data. The Second Edition is also an ideal textbook for undergraduate and graduate-level courses in data analysis and data mining and is appropriate for cross-disciplinary courses found within computer science and engineering departments.

A hands-on guide to making valuable decisions from data using advanced data mining methods and techniques This second installment in the Making Sense of Data series continues to explore a diverse range of commonly used approaches to making and communicating decisions from data. Delving into more technical topics, this book equips readers with advanced data mining methods that are needed to successfully translate raw data into smart decisions across various fields of research including business, engineering, finance, and the social sciences. Following a comprehensive introduction that details how to define a problem, perform an analysis, and deploy the results, Making Sense of Data II addresses the following key techniques for advanced data analysis: Data Visualization reviews principles and methods for understanding and communicating data through the use of visualization including single variables, the relationship between two or more variables, groupings in data, and dynamic approaches to interacting with data through graphical user interfaces. Clustering outlines common approaches to clustering data sets and provides detailed explanations of methods for determining the distance between observations and procedures for clustering observations. Agglomerative hierarchical clustering, partitioned-based clustering, and fuzzy clustering are also discussed. Predictive Analytics presents a discussion on how to build and assess models, along with a series of predictive analytics that can be used in a variety of situations including principal component analysis, multiple linear regression, discriminate analysis, logistic regression, and Naïve Bayes. Applications demonstrates the current uses of data mining across a wide range of industries and features case studies that illustrate the related applications in real-world scenarios. Each method is discussed within the context of a data mining process including defining the problem and deploying the results, and readers are provided with guidance on when and how each method should be used. The related Web site for the series (www.makingsenseofdata.com) provides a hands-on data analysis and data mining experience. Readers wishing to gain more practical experience will benefit from the tutorial section of the book in conjunction with the TraceisTM software, which is freely available online. With its comprehensive collection of advanced data mining methods coupled with tutorials for applications in a range of fields, Making Sense of Data II is an indispensable book for courses on data analysis and data mining at the upper-undergraduate and graduate levels. It also serves as a valuable reference for researchers and professionals who are interested in learning how to accomplish effective decision making from data and understanding if data analysis and data mining methods could help their organization.

Concepts and Experimental Protocols of Modelling and Informatics in Drug Design discusses each experimental protocol utilized in the field of bioinformatics, focusing especially on computer modeling for drug development. It helps the user in understanding the field of computer-aided molecular modeling (CAMM) by presenting solved exercises and examples. The book discusses topics such as fundamentals of molecular modeling, QSAR model generation, protein databases and how to use them to select and analyze protein structure, and pharmacophore modeling for drug targets. Additionally, it discusses data retrieval system, molecular surfaces, and freeware and online servers. The book is a valuable source for graduate students and researchers on bioinformatics, molecular modeling, biotechnology and several members of biomedical field who need to understand more about computer-aided molecular modeling. - Presents exercises with solutions to aid readers in validating their own protocol - Brings a thorough interpretation of results of each exercise to help readers compare them to their own study - Explains each parameter utilized in the algorithms to help readers understand and manipulate various features of molecules and target protein to design their study

Accessibly written by a team of international authors, the Encyclopedia of Environmental Change provides a gateway to the complex facts, concepts, techniques, methodology and philosophy of environmental change. This three-volume set illustrates and examines topics within this dynamic and rapidly changing interdisciplinary field. The encyclopedia includes all of the following aspects of environmental change: Diverse evidence of environmental change, including climate change and changes on land and in the oceans Underlying natural and anthropogenic causes and mechanisms Wide-ranging local, regional and global impacts from the polar regions to the tropics Responses of geo-ecosystems and human-environmental systems in the face of past, present and future environmental change Approaches, methodologies and techniques used for reconstructing, dating, monitoring, modelling, projecting and predicting change Social, economic and political dimensions of environmental issues, environmental conservation and management and environmental policy Over 4,000 entries explore the following key themes and more: Conservation Demographic change Environmental management Environmental policy Environmental security Food security Glaciation Green Revolution Human impact on environment Industrialization Landuse change Military impacts on environment Mining and mining impacts Nuclear energy Pollution Renewable resources Solar energy Sustainability Tourism Trade Water resources Water security Wildlife conservation The comprehensive coverage of terminology includes layers of entries ranging from one-line definitions to short essays, making this an invaluable companion for any student of physical geography, environmental geography or environmental sciences.