This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Elin R. Sigurdson, is devoted to Clinical Trials in Surgical Oncology. Dr. Sigurdson has assembled expert authors to review the following topics: Commentary on Randomized Controlled Trials; Randomized Clinical Trials in Soft Tissue Sarcoma; Randomized Clinical Trials in Gastrointestinal Stromal Tumors; Randomized Clinical Trials in Melanoma; Randomized Clinical Trials in Breast Cancer; Randomized Clinical Trials in Gastroesophageal Carcinoma; Randomized Clinical Trials in Hepatocellular Carcinoma; An Update on Randomized Clinical Trials in Advanced and Metastatic Colorectal Carcinoma; Randomized Clinical Trials in Colon and Rectal Cancer; Randomized Clinical Trials in Anal Cancers; The Elderly in Randomized Clinical Trials; Hereditary Syndromes in Clinical Trials; Future Clinical Trials: Genetically Driven Trials; Randomized Clinical Trials in Neuroendocrine Tumors, and more!

In this issue of Surgical Oncology Clinics, guest editors Drs. Adam Yopp and Maria B. Majella Doyle bring their considerable expertise to the topic of Hepatocellular Carcinoma. Top experts in the field explore promising recent advances in the treatment of all stages of hepatocellular carcinoma (HCC), neoadjuvant or downstaging therapy, the role of LI-RADS in hepatocellular carcinoma, surveillance of hepatocellular carcinoma, liver transplantation, and more. Contains 13 relevant, practice-oriented topics, including the changing epidemiology of HCC within the US and worldwide; HCC surveillance: evidence-based tailored approach; surgical resection outside early stage HCC; minimally invasive techniques for HCC resection; overview of current HCC staging systems: is there an optimal system?; and more. Provides in-depth clinical reviews on hepatocellular carcinoma, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Surgical Oncology Clinics, guest editor Oluwadamilola "Lola" Fayanju brings considerable expertise to the topic of Disparities and Determinants of Health in Surgical Oncology. Provides in-depth, clinical reviews on the latest updates on Disparities and Determinants of Health in Surgical Oncology, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This issue of the Surgical Oncology Clinics will review the important clinical trials from the past eight years in following topics: breast cancer, soft tissue sarcoma, rectal and anal carcinoma, pancreatic adenocarcinoma, hepatocellular carcinoma, gastric cancer, esophageal cancer, colon cancer, advanced and metastatic colorectal carcinoma, gastrointestinal stromal tumors, and melanoma.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

In this issue of Surgical Oncology Clinics of North America, Guest Editor Clifford Ko, MD has assembled the top experts concerning Outcomes Research in Oncology. Topics in this issue will include: Currently Available Quality Initiatives in Surgical Oncology; Variation in Mortality After High Risk Cancer Surgery: Failure to Rescue; Readmission as a Quality Measure Following High Risk Cancer Surgery; Randomized Controlled Trials in Surgical Oncology: Where Do We Stand?; Lymph Node Staging in GI Malignancies; Racial and Socioeconomic Disparities in Cancer Care; Patient Safety in Surgical Oncology: Perspective from the Operating Room; Value Based Health Care: A Surgical Oncologist Perspective; Monitoring the Delivery of Cancer Care: Commission on Cancer and National Cancer Data Base; Prediction Tools in Surgical Oncology; Collaboration With the Community Cancer Center: Benefit for All; and Evaluating the Appropriateness of Cancer Care in the United States.