Cool is cool and geek is geek, and at Eldridge the two definitely do not mix. Sari and Jess are best friends and total opposites. They've liked each other ever since they discovered that they are the only two normal people at Eldridge Alternative. As they prepare to face the trials of ninth grade, Sari is psyched. Jess is not. How can she face the Prada Mafia, the most evil clique in school? Or Mr. McGuiness's unnervingly long nose hair? What if something really interesting happens to Sari and nothing whatsoever happens to Jess? But not even Jess can predict the mayhem that erupts when Sari falls madly in love with David Cole. David is a senior. He's been dating Thea Melendez for forever. So he couldn't possibly be interested in Sari. Or could he? And if he is, where does that leave Jess?

Miranda Smith isn't surprised to discover a cache of racy photographs in her husband's desk--after all, he is the president of Ballantyne Bras. But she's more than shocked to realize it's his buff, burly body encased in the red satin bustier and matching bikini panties...and he's nowhere to be found. Neither is their life savings nor the company coffers. Thus begins Miranda's hilarious, frantic scramble to unravel the mystery behind her husband's disappearance, illegal accounting practices, and penchant for wearing silky teddies and kitten heels.

"Cleavage is very 1960s: it shows off the new permissiveness. (Look! we can reveal most of Elizabeth Taylor's breasts!) Cleavage is not nudity. Cleavage is a promise: not sight, but on the verge of sight." [p. 138] In this brilliantly shrewd, hilarious collection of essays, cultural critic and acclaimed writer Wayne Koestenbaum exposes all that provokes, intimidates, heartens, and arouses us in matters of style, celebrity, obscenity, and art. Armed with a bold curiosity, a stinging wit, and a subversive sense of wordplay, Koestenbaum reflects on a dazzling array of subjects. Here are the outsized emotions inflamed by Sophia Loren, Robert Mapplethorpe, and locker-room nudity . . . vivid dreams of flirting with Bill Clinton and resurrecting Bette Davis from the dead . . . the intangible joys of thrifting . . . the true meaning of masculinity . . . and the indelible sensation that two scoops of vanilla flesh, heaving incongruously in a 70-millimeter musical, made on a young boy of impressionable age. From the rigors of a day spent with Melanie Griffith ("Melanie Time") to the healing powers of a gray Prada suit ("Diary of a Suit") to moving meditations on the importance of reading ("Why I Read"), this volume is an irresistible exploration of culture and identity in America. If celebrity is--as Koestenbaum suggests--an earthquake, then Cleavage is the aftershock.

Embryo cleavage experiences a series of critical events and remarkable epigenetic modifications, especially morphological change and gene expression. The development of current assisted reproductive technology has created some new observations and novel discoveries in cleavage embryos. This book updates some new technologies and methods on the study of cleavage embryos to select high-quality embryos for transfer and improve embryo implantation and pregnancy. Major contents include embryo cleavage morphokinetics based on time-lapse imaging, gene expression of cleavage embryo and noninvasive assessment, and improving embryo cleavage technology. Thus, this book will greatly add new information for embryologists to select good-quality embryos for transfer to improve human embryo transfer pregnancy rate.

Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review. Table of Contents: Introduction / Oogenesis: From Germline Stem Cells to Germline Cysts / Oocyte Polarity and the Embryonic Axes: The Balbiani Body, an Ancient Oocyte Asymmetry / Preparing Developmentally Competent Eggs / Egg Activation / Blocking Polyspermy / Cleavage/ Mitosis: Going Multicellular / Maternal-Zygotic Transition / Reprogramming: Epigenetic Modifications and Zygotic Genome Activation / Dorsal-Ventral Axis Formation before Zygotic Genome Activation in Zebrafish and Frogs / Maternal TGF-β and the Dorsal-Ventral Embryonic Axis / Maternal Control After Zygotic Genome Activation / Compensation by Stable Maternal Proteins / Maternal Contributions to Germline Establishment or Maintenance / Perspective / Acknowledgments / References

She didn’t hatch out of an eagle’s nest, circa One Million Years B.C., clad in a skimpy fur bikini. She didn’t aspire to fame as a sex symbol. Yet, for many years after making her Hollywood entrance as every man’s fantasy, Raquel Welch was best known for her beauty and sex appeal. A private person, she allowed people to draw their own conclusions from her public image. Now, Raquel Welch is ready to speak her mind. And, with the luxury of hindsight and the benefit of experience, she has plenty to share about the art of being a woman—even men will find it enlightening to read about what makes her tick. In Beyond the Cleavage, Raquel Welch talks, woman to woman, about her views on all that comes with being a member of the female sex—love, sex, style, health, body image, career, family, forgiveness, aging, and coming of age. Looking back on her life, she lets women in on her childhood, dominated by a volatile father; her first love, marriage, and divorce; her early struggles as a single working mother in Hollywood; her battles for roles and respect as an actress; and her daring decision never to lie about her age. Looking forward, she offers women a compass to guide them at every crossroad of life, from menopause through the empty nest years, to dating younger men and beyond. Along with bringing baby boomers into her confidence—she offers essential tips for staying motivated and positive past fifty, as well as divulging her secrets for fabulous hair and makeup—she even talks to today’s younger generation of women about the importance of carrying themselves with dignity and self-respect. With warmth, humor, conviction, and honesty, Raquel reveals her approach to preventative aging, her life-changing commitment to yoga, her recipe for eating right, her skincare regimen, her flair for fashion, and much more. Deeply personal (Welch wrote every word herself—no ghostwriter), Beyond the Cleavage is Raquel Welch’s gift to every woman who longs to look and feel her best, and be at peace with herself.