This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Describes the anatomy and functions of the human circulatory system and how it responds to increased activity, the microgravity of space, and other changes.

Discusses the circulatory system and ways to keep your heart healthy, and shows a map of blood's route around the body.

The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.

Developed by a pediatrician, this book focuses on the amazing design and functionality of the human body’s circulatory system. You will discover amazing facts like: The human heart beats 100,000 times a day, and one drop of blood has 5 million red blood cells in it A timeline of important discoveries and innovators as well as key anatomical terms and concepts Discussions of disease and proper care for optimal health! The third book in the popular elementary anatomy series God’s Wondrous Machine, focuses on the heart, blood, and blood vessels that make up the body’s circulatory system. Understanding the mechanics of this system in transporting nutrients, blood, chemicals, and more to cells within the body is key to understanding how it helps fight disease as well as maintain a properly balanced temperature. Readers learn how the deliberate design of their bodies enables it to function as it should, just as God meant for it to.

Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.