Introduction to Epigenetics

Introduction to Epigenetics
Title Introduction to Epigenetics PDF eBook
Author Renato Paro
Publisher Springer Nature
Pages 215
Release 2021-03-23
Genre Science
ISBN 3030686701

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This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease

Molecular Biology of the Cell

Molecular Biology of the Cell
Title Molecular Biology of the Cell PDF eBook
Author
Publisher
Pages 0
Release 2002
Genre Cells
ISBN 9780815332183

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Fundamentals of Chromatin

Fundamentals of Chromatin
Title Fundamentals of Chromatin PDF eBook
Author Jerry L. Workman
Publisher Springer Science & Business Media
Pages 594
Release 2013-12-04
Genre Medical
ISBN 1461486246

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​​​​​​​​​​​​​While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin. ​Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication. The audience for this book is mainly newly established scientists ​and graduate students. Rather than going into the more specific areas of recent research on chromatin the chapters in this book give a strong, updated groundwork about the topic. Some the fundamentals that this book will cover include the structure of chromatin and biochemistry and the enzyme complexes that manage it.

Chromatin Regulation and Dynamics

Chromatin Regulation and Dynamics
Title Chromatin Regulation and Dynamics PDF eBook
Author Anita Göndör
Publisher Academic Press
Pages 498
Release 2016-10-25
Genre Science
ISBN 0128034025

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Chromatin Regulation and Dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The final chapters discuss the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin Regulation and Dynamics, part of the Translational Epigenetics series, facilitates the flow of information between research areas such as chromatin regulation, developmental biology, and epidemiology by focusing on recent findings of the fast-moving field of chromatin regulation. - Presents and discusses novel principles of chromatin regulation and dynamics with a cross-disciplinary perspective - Promotes crosstalk between basic sciences and their applications in medicine - Provides a framework for future studies on complex diseases by integrating various aspects of chromatin biology with cellular metabolic states, with an emphasis on the dynamic nature of chromatin and stochastic principles - Integrates knowledge on the dynamic regulation of primary chromatin fiber with 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes

The Nucleosome

The Nucleosome
Title The Nucleosome PDF eBook
Author A.P. Wolffe
Publisher Elsevier
Pages 265
Release 1996-01-08
Genre Science
ISBN 0080537847

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This is the first in a series of volumes concerning the properties of the eukaryotic nucleus. Contributions from several of the most active laboratories are brought together to present a focused overview of a selected aspect of nuclear structure and function.

Chromatin and Chromatin Remodeling Enzymes Part C

Chromatin and Chromatin Remodeling Enzymes Part C
Title Chromatin and Chromatin Remodeling Enzymes Part C PDF eBook
Author Carl Wu
Publisher Elsevier
Pages 585
Release 2004-04-07
Genre Science
ISBN 0080497152

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DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the chromatin remodelling enzymes play an important role in gene transcription. - Genetic assays of chromatin modification and remodeling - Histone modifying enzymes - ATP-dependent chromatin remodeling enzymes

Chromatin and Chromatin Remodeling Enzymes, Part B

Chromatin and Chromatin Remodeling Enzymes, Part B
Title Chromatin and Chromatin Remodeling Enzymes, Part B PDF eBook
Author Carl Wu
Publisher Elsevier
Pages 497
Release 2004-03-07
Genre Science
ISBN 0080497144

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DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the Chromatin remodelling enzymes play an important role in gene transcription.