"A powerful strategy for the synthesis of functional nanomaterials involves the assembly of both inorganic and organic nanostructured components to result in a hybrid material with intrinsically tailored properties. Achieving desired hybrid material structure, function, and reproducibility necessitates the investigation of methods to establish and preserve monodispersity, chemical functionality, and required properties within the component nanomaterials. Described herein is work on biological and synthetic nanostructures as potential building blocks for nanostructured materials by design.In the first part of this thesis we present our investigation into the functional properties and chemical control of two bio-organic materials: tobacco mosaic virus coat protein and the reversibly photoswitchable protein Dronpa. Attachment of a hexahistidine tag to tobacco mosaic virus coat protein by genetic engineering resulted in unprecedented assembly behavior for the coat protein, forming nanostructured rafts, nanofibers, and hexagonally packed disks in addition to structures normally observed for the wild-type coat protein. The type of assembly formed was controlled by the addition of ethanol or nickel(II)-nitrilotriacetic acid, enabling the modified protein to serve as a reliable template for the future preparation of hybrid nanostructured materials. Scanning tunnelling microscopy and spectroscopy obtained of Dronpa monolayers on gold allowed us to define the relationships between Dronpa fluorescence switching, orientation, and conductance. Modification of Dronpa with a hexahistidine tag resulted in better self-assembled monolayers of Dronpa, and also demonstrated the influence of molecular orientation on protein conductivity. Recent applications of magnetic iron oxide nanoparticles for separation, catalysis, and magnetic imaging have stimulated interest in the synthesis and modification of ultrasmall water-soluble iron oxide nanoparticles (the topic of Chapters 4 and 5) as components for the preparation of functional materials. In response, an efficient ligand exchange method for the synthesis of aqueous stable magnetic iron oxide nanoparticles was developed to yield monodisperse nanoparticles functionalized with the small, highly charged ligands dopamine and Tiron. Motivated by the need to better understand the nature of ligand binding to iron oxide, model benzoic acid derivatives and catechol-based ligands were reacted with oleic acid stabilized iron oxide nanoparticles. Fourier transform infrared spectroscopy was used to examine the ligand exchange, purification, and the resulting complexes. The correlations observed between features in the obtained spectra and solubility of the ligand-stabilized nanoparticles enabled the assignment of binding modes for the series of model ligands--which will assist in the rational design of custom ligands for iron oxide. Advances in monodispersity, chemical control, reaction monitoring, and knowledge gained regarding the structure-functional relationships of the bio-organic and inorganic materials examined in this work will assist in the design of future hybrid inorganic-organic nanostructured materials. " --

This ready reference is the first to collate the interdisciplinary knowledge from materials science, bioengineering and nanotechnology to give an in-depth overview of the topic. As such, it provides broad coverage of combinations between inorganic materials and such key biological structures as proteins, enzymes, DNA, or biopolymers. With its treatment of various application directions, including bioelectronic interfacing, tissue repair, porous membranes, sensors, nanocontainers, and DNA engineering, this is essential reading for materials engineers, medical researchers, catalytic chemists, biologists, and those working in the biotechnological and semiconductor industries.

The combination of supramolecular chemistry, inorganic solids, and nanotechnology has already led to significant advances in many areas such as sensing, controlled motion, and delivery. By making possible an unprecedented tunability of the properties of nanomaterials, these techniques open up whole new areas of application for future supramolecular concepts. The Supramolecular Chemistry of Organic–Inorganic Hybrid Materials gathers current knowledge on the subject and provides an overview of the present state and upcoming challenges in this rapidly growing, highly cross- or interdisciplinary research field. The book details how these designed materials can improve existing materials or generate novel functional features such as chemical amplification, cooperative binding and signal enhancement that are difficult or not at all achievable by classical organic supramolecular chemistry. It also discusses issues related to nanofabrication or nanotechnology such as the directed and controlled assembly or disassembly, biomimetic functions and strategies, and the gating and switching of surface functions or morphology.

There are several well-known books on the market that cover biomaterials in a general way, but none provide adequate focus on the future of and potential for actual uses of emerging nanontechnology in this burgeoning field.Biomaterials: A Nano Approach is written from a multi-disciplinary point of view that integrates aspects of materials science a

Cubes, triangular prisms, nano-acorn, nano-centipedes, nanoshells, nano-whiskers. . . . Now that we can create nanoparticles in a wide variety of shapes and morphologies, comes the next challenge: finding ways to organize this collection of particles into larger and more complex systems. Nanoparticle Assemblies and Superstructures, edit

- The first reference work ever published on nanostructured biomaterials and their applications. - A unique source of in-depth knowledge of recent advances in applications of nanostructured biomaterials. Most up-to-date emerging aspects of nanobiomaterials and their applications in the field of nanotechnology. - Contains 33 state-of-the-art chapters written by over 70 internationally renowned experts from 10 countries. - About 5,000 bibliographic citations and hundreds of illustrations, figures, tables, chemical structures and equations.

Nanoparticles are the building blocks for nanotechnology; they are better built, long lasting, cleaner, safer, and smarter products for use across industries, including communications, medicine, transportation, agriculture and other industries. Controlled size, shape, composition, crystallinity, and structure-dependent properties govern the unique properties of nanotechnology. Bio-Nanoparticles: Biosynthesis and Sustainable Biotechnological Implications explores both the basics of and advancements in nanoparticle biosynthesis. The text introduces the reader to a variety of microorganisms able to synthesize nanoparticles, provides an overview of the methodologies applied to biosynthesize nanoparticles for medical and commercial use, and gives an overview of regulations governing their use. Authored by leaders in the field, Bio-Nanoparticles: Biosynthesis and Sustainable Biotechnological Implications bridges the gap between biology and technology, and is an invaluable resource for students and researchers alike.