This book presents the latest research in computational methods for modeling and simulating brain disorders. In particular, it shows how mathematical models can be used to study the relationship between a given disorder and the specific brain structure associated with that disorder. It also describes the emerging field of computational psychiatry, including the study of pathological behavior due to impaired functional connectivity, pathophysiological activity, and/or aberrant decision-making. Further, it discusses the data analysis techniques that will be required to analyze the increasing amount of data being generated about the brain. Lastly, the book offers some tips on the application of computational models in the field of quantitative systems pharmacology. Mainly written for computational scientists eager to discover new application fields for their model, this book also benefits neurologists and psychiatrists wanting to learn about new methods.

"Discusses the principles of operation of photovoltaic devices, their limitations, choice of materials and maximum efficiencies"--

"Recent advancements in generation of intense X-ray laser ultrashort pulses open opportunities for particle acceleration in solid-state plasmas. Wakefield acceleration in crystals or carbon nanotubes shows promise of unmatched ultra-high accelerating gradients and possibility to shape the future of high energy physics colliders. This book summarizes the discussions of the "Workshop on Beam Acceleration in Crystals and Nanostructures" (Fermilab, June 24-25, 2019), presents next steps in theory and modeling and outlines major physics and technology challenges toward proof-of-principle demonstration experiments"--Publisher's website.

From its early beginnings at SLAC in the 1970's, the study of nucleon spin structure using polarized lepton beams and polarized nucleon targets has become increasingly important in nuclear and particle physics, with current experiments at several of the world's high energy laboratories (CERN, DESY and SLAC) and with enormous related theoretical studies. The understanding of the fascinating but complicated problem of nucleon spin structure has progressed substantially, but fundamental questions remain and it can be confidently predicted that future activity will be high. The Erice Course on The Spin Structure of the Nucleon covered both the experimental and theoretical aspects of the subject, and this volume includes the lectures given at the School. In many cases the lecture material has been extended and updated by the authors. In addition, several recent publications on experimental work have been added in an appendix.

After a historical consideration of the types and evolution of accelerators the physics of particle beams is provided in detail. Topics dealt with comprise linear and nonlinear beam dynamics, collective phenomena in beams, and interactions of beams with the surroundings. The design and principles of synchrotrons, circular and linear colliders, and of linear accelerators are discussed next. Also technological aspects of accelerators (magnets, RF cavities, cryogenics, power supply, vacuum, beam instrumentation, injection and extraction) are reviewed, as well as accelerator operation (parameter control, beam feedback system, orbit correction, luminosity optimization). After introducing the largest accelerators and colliders of their times the application of accelerators and storage rings in industry, medicine, basic science, and energy research is discussed, including also synchrotron radiation sources and spallation sources. Finally, cosmic accelerators and an outlook for the future are given.

It has been over 100 years since the presentation of the Theory of General Relativity by Albert Einstein, in its final formulation, to the Royal Prussian Academy of Sciences. To celebrate 100 years of general relativity, World Scientific publishes this volume with a dual goal: to assess the current status of the field of general relativity in broad terms, and discuss future directions. The volume thus consists of broad overviews summarizing major developments over the past decades and their perspective contributions.