Characterisation and Design of Tissue Scaffolds offers scientists a useful guide on the characterization of tissue scaffolds, detailing what needs to be measured and why, how such measurements can be made, and addressing industrially important issues. Part one provides readers with information on the fundamental considerations in the characterization of tissue scaffolds, while other sections detail how to prepare tissue scaffolds, discuss techniques in characterization, and present practical considerations for manufacturers. - Summarizes concepts and current practice in the characterization and design of tissue scaffolds - Discusses design and preparation of scaffolds - Details how to prepare tissue scaffolds, discusses techniques in characterization, and presents practical considerations for manufacturers

In joint replacement surgery with suboptimal bone, allograft materials are often used to achieve biological fixation of the metallic implant to the host bone and reducing the implant fixation time. The most commonly used techniques are cemented and hydroxyapatite (HA)-coated metallic implants. Typically, HA coatings are suggested for patients with better bone stock, whereas recommended implant fixation process for most other osteoporotic patients is bone cements. In general, there is a long-standing need to improve the performance of hip and other devices for longer in vivo implant lifetime that can help in reducing the number of revision surgeries, as well as minimizing physical and mental trauma to the patient. To achieve these goals, it is important to understand the mechanical and biological properties of coatings that can influence not only its short- and long-term bioactivity but also life span in vivo. Over the years, it has been recognized that the stability of a coated implant is governed by its physical and mechanical properties. A coating that separates from the implant provides no advantage over an uncoated implant and undesirable due to problems with debris materials, which can lead to osteolysis. Therefore, it is important to properly characterize the coated implants in terms of its physical and mechanical properties. In this chapter, specific details on coating characterization techniques including sample dimensions, sample preparation, experimental procedure and data interpretation are discussed. In particular, the standards and requirements of regulatory organizations are presented elucidating the significance and use of each characterization. It is important to appreciate that mechanical properties of coatings can only be determined with certain coating specification such as coating thickness. This chapter is designed even for non-experts to follow mechanical property characterizations of coatings on medical implants.

This volume provides an in-depth introduction to 3D printing and biofabrication and covers the recent advances in additive manufacturing for tissue engineering. The book is divided into two parts, the first part on 3D printing discusses conventional approaches in additive manufacturing aimed at fabrication of structures, which are seeded with cells in a subsequent step. The second part on biofabrication presents processes which integrate living cells into the fabrication process.

Revolutionize the search for sustainable industry with these biodegradable materials The search for biodegradable materials has become an increasingly essential component of the global response to climate change and the urgent need for more sustainable industrial processes. Biodegradable polymers, either synthetic or natural, have become an explosive research subject as their applications in food, medicinal, and pharmaceutical industries become more and more apparent. There is an urgent need for chemists and other professionals working in these industries to understand the range of available biopolymers and how to use them. Biopolymers in Pharmaceutical and Food Applications presents an overview of all currently-known food-safe polymers and their applications for food and pharmaceutical technology. Its grasp of recent sustainable trends in biopolymer production and distribution make it a one-stop shop for researchers and industry professionals looking to understand the future of sustainable food production, pharmaceutical and cosmetic applications. Comprehensive and accessible, it has never been timelier as a contribution to these key industries. Readers of the two volumes of Biopolymers in Pharmaceutical and Food Applications will also find: Treatment of biopolymers including collagen, chitosan, carrageenan, and more Detailed discussion of drug delivery systems incorporating plant- and animal-based biopolymers An editor with extensive research and teaching experience in biopolymer and pharmaceutical research Biopolymers in Pharmaceutical and Food Applications is ideal for polymer chemists, pharmaceutical chemists, food scientists, and any other researcher looking to work with biodegradable polymers.

Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated. With its distinguished editors and international team of contributors, Tissue Engineering using Ceramics and Polymers reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. Part one discusses general issues such as ceramic and polymeric biomaterials, scaffolds, transplantation of engineered cells, surface modification and drug delivery. Later chapters review characterisation using x-ray photoelectron spectroscopy and secondary ion mass spectrometry as well as environmental scanning electron microscopy and Raman micro-spectroscopy. Chapters in part two analyse bone regeneration and specific types of tissue engineering and repair such as cardiac, intervertebral disc, skin, kidney and bladder tissue. The book concludes with the coverage of themes such as nerve bioengineering and the micromechanics of hydroxyapatite-based biomaterials and tissue scaffolds. Tissue Engineering using Ceramics and Polymers is an innovative reference for professionals and academics involved in the field of tissue engineering. - An innovative and up-to-date reference for professionals and academics - Environmental scanning electron microscopy is discussed - Analyses bone regeneration and specific types of tisue engineering

Three-dimensional (3D) printing enables the fabrication of tissue-engineered constructs and devices from a patient’s own medical data, leading to the creation of anatomically matched and patient-specific constructs. There is a growing interest in applying 3D printing technologies in the fields of tissue engineering and regenerative medicine. The main printing methods include extrusion-based, vat photopolymerization, droplet-based, and powder-based printing. A variety of materials have been used for printing, from metal alloys and ceramics to polymers and elastomers as well as from hydrogels to extracellular matrix proteins. More recently, bioprinting, a subcategory of 3D printing, has enabled the precise assembly of cell-laden biomaterials (i.e., bioinks) for the construction of complex 3D functional living tissues or artificial organs. In this Special Issue, we aim to capture state-of-the-art research papers and the most current review papers focusing on 3D printing for tissue engineering and regenerative medicine. In particular, we seek novel studies on the development of 3D printing and bioprinting approaches, developing printable materials (inks and bioinks), and utilizing 3D-printed scaffolds for tissue engineering and regenerative medicine applications. These applications are not limited to but include scaffolds for in vivo tissue regeneration and tissue analogues for in vitro disease modeling and/or drug screening.

Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t