Cell to Cell Signalling: From Experiments to Theoretical Models is a collection of papers from a NATO Workshop conducted in Belgium in September 1988. The book discusses nerve cells and neural networks involved in signal transfers. The works of Hodgkin and Huxley presents a prototypic combination between experimental and theoretical approaches. The book discusses the coupling process found between secretory cells that modify their behavior. The text also analyzes morphogenesis and development, and then emphasizes the pattern formation found in Drosophila and in the amphibian embryo. The text also cite examples of immunological modeling that is related to the dynamics of immune networks based on idiotypic regulation. One paper analyzes the immune dynamism of HIV infection. The text notes that hormone signaling can be attributed as responsible for intercellular communication. Another paper examines how the dominant follicle in the ovarian cycle is selected, as well as the effectiveness of hormone secretion responsible for encoding the frequency of occurrence of periodic signals. The book also discusses heart signal sources such as cardiac dynamics and the response of periodically excited cardiac cells. The text can prove valuable for practioners in the field of neurology and cardiovascular medicine, and for researchers in molecular biology and molecular chemistry.

Signalling within and between cells is an essential part of many biological processes, from the development of the body to the activity of our immune system. Cell Signalling, Third Edition, presents a carefully structured introduction to this intricate subject, introducing those conserved features that underlie many different extra- and intracellular signalling systems. Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms before examining how these components come together to create signalling pathways, which are so crucial to the survival of many living organisms. The text is enhanced by two-color artwork and 3-D protein models. A Companion Website provides resources for students and instructors.

Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. - Contains over 350 chapters of comprehensive coverage on cell signaling - Includes discussion on topics from ligand/receptor interactions to organ/organism responses - Provides user-friendly, well-illustrated, reputable content by experts in the field

This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)

Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Cell Signaling presents the principles and components that underlie all known signaling processes. It provides undergraduate and graduate students the conceptual tools needed to make sense of the dizzying array of pathways used by the cell to communicate. By emphasizing the common design principles, components, and logic that drives all signa