This Research Topic aims to collect all the Case Reports submitted to the General Cardiovascular Medicine section. All the Case Reports submitted to this collection will be personally assessed by the Specialty Chief Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it. Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only Case Reports that are original and significantly advance the field will be considered: 1) RARE case with TYPICAL features 2) FREQUENT case with ATYPICAL features 3) Cases with a convincing response to new treatments, i.e. single case of off-label use

This Research Topic aims to collect all case reports submitted to structural interventional cardiology section. All the case reports submitted to this collection will be assessed by a senior Associate Editor before beginning the peer review process. Please make sure your article adheres to the following guidelines before submitting. Case reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only case reports that are original and significantly advance the field will be considered: 1) RARE case with TYPICAL features 2) FREQUENT case with TYPICAL features 3) Cases with a convincing response to new treatments Case report format: • Maximum word count: 3000 words • Title: Case Report: "area of focus" • Abstract • Introduction: including what is unique about the case and medical literature references. • Case description: including de-identified patient information, relevant physical examination and other clinical findings, relevant past interventions, and their outcomes • A figure or table showcasing a timeline with relevant data from the episode of care • Diagnostic assessment, details on the therapeutic intervention, follow-up, and outcomes as specified in the CARE guidelines • Discussion: strengths and limitations of the approach to the case, discussion of the relevant medical literature (similar and contrasting cases), take-away lessons from the case • Patient perspectives