The sodium channel, a ubiquitous member of the cardiac, neural, and muscular conduction systems, has been implicated in the pathogenesis of an array of human diseases. Mutations associated with the cardiac sodium channel are responsible for a wide spectrum of disorders. The cardiac sodium channel and associated disorders are comprehensively examined in this issues of the Cardiac Electrophysiology Clinics.

This issue of the Cardiac Electrophysiology Clinics entitled “Ventricular Arrhythmias in Apparently Normal Hearts is being edited by Drs. Frank M. Bogun, Thomas Crawford, and Rakesh Latchamsetty. The issue will cover topics including, the mechanisms of ventricular arrhythmias, the role of genetic testing, papillary muscle arrhythmias, fascicular arrhythmias, exercised induced VT, VF, and SCD in the normal heart, and various management techniques.

Long QT syndrome is a heart rhythm disorder that can cause fast, chaotic heartbeats. In some cases, long QT syndrome can cause sudden death. Long QT syndrome may result from a genetic mutation or be caused by certain medications and medical conditions. The condition is treatable with medication, surgery, or an implantable device. Because it may have serious consequences, it’s important for electrophysiologists to know about long QT syndrome.

The sodium channel, a ubiquitous member of the cardiac, neural, and muscular conduction systems, has been implicated in the pathogenesis of an array of human diseases. Mutations associated with the cardiac sodium channel are responsible for a wide spectrum of disorders. The cardiac sodium channel and associated disorders are comprehensively examined in this issues of the Cardiac Electrophysiology Clinics.

This issue of Cardiac Electrophysiology Clinics, edited by Drs. Mohammad Shenasa and Stanley Nattel, will review Cardiac Potassium Channel Disorders in depth. Topics covered include but are not limited to: Molecular Biology of Cardiac Potassium Channels; Genetic Control of Potassium Channels; Potassium Channel Remodeling in Heart Disease; Gender-specific Effects of Potassium Channel Blockers; Pharmacogenetics of Potassium Channel Blockers; Multichannel Blockers; Selective Potassium Channel Blockers; and Proarrhythmic and Torsadogenic Effects of Potassium Channel Blockers in Patients.

In this issue of Cardiac Electrophysiology Clinics, Guest Editors Eric N. Prystowsky and Benzy Padanilam bring their considerable expertise to the topic of Cardiac Conduction System Disorders. Top experts in the field cover key topics such as sinus node abnormalities, electrocardiography of AV block, AV conduction, pacemaker-induced cardiomyopathy, and more. Provides in-depth, clinical reviews on Cardiac Conduction System Disorders, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 16 relevant, practice-oriented topics including Anatomy and Pathology of the cardiac conduction system; Physiologic variants of cardiac conduction; Genetic abnormalities of SA node and AV conduction?; Epidemiology of Prolonged PR interval; and more.

This issue of Cardiac Electrophysiology Clinics examines electrocardiography of complex arrhythmias. Topics include concealed conduction, right and left atrial macroreentrant tachycardias, focal atrial fachycardias, AV nodal and AV reentrant tachycardia, wide complex tachycardias, ventricular tachycardia in CAD, ECG characteristics of outflow tract VT, fascicular tachycardias, VT in non-ischemic dilated cardiomyopathy, VT originating from unusual sites, incessant VT and VT storms, ECG characteristics of TdP, VT in ARVC, and ventricular arrhythmia in inherited channelopathies, arrrhythmias in complex congenital heart disease, AV conduction disease and block, electrocardiographic analysis of paced rhythms.