For the first time, this invaluable book shows how cardiac perfusion and pumping can be quantified and correlated. Self-contained and unified in presentation, the explanations in the compendium are detailed enough to capture the reader's curiosity and complete enough to provide the background material to explore further into the subject.Mathematically rigorous and clinically oriented, the book is a major resource for biomedical engineers, cardiologists, cardiac surgeons and clinicians. For students, it is an ideal textbook for senior-level courses in cardiovascular engineering.

This book highlights recent technological advances, reviews and applications in the field of cardiovascular engineering, including medical imaging, signal processing and informatics, biomechanics, as well as biomaterials. It discusses the use of biomaterials and 3D printing for tissue-engineered heart valves, and also presents a unique combination of engineering and clinical approaches to solve cardiovascular problems. This book is a valuable resource for students, lecturers and researchers in the field of biomedical engineering.

This book provides a comprehensive overview of mechanical circulatory support of the failing heart in adults and children. The book uniquely combines engineering knowledge and the clinician’s perspective into a single resource, while also providing insights into current and future development of mechanical circulatory support technology, such as ventricular assist devices, the total artificial heart and catheter-based technologies for heart failure. Topics featured in this book include: The history of mechanical circulatory device development. Fundamentals of hemodynamics support. Clinical management of mechanical circulatory devices. Surgical implantation techniques. Current limitations of device therapies in advanced heart failure. Advanced and novel devices in the development pipeline. Opportunities for advancement in the field. Mechanical Support for Heart Failure: Current Solutions and New Technologies is a must-have resource for not only physicians, residents, fellows, and medical students in cardiology and cardiac surgery, but also clinical and basic researchers in biomedical engineering with an interest in mechanical circulatory support, heart failure, and new technological applications in medicine.

Cardiology Science and Technology comprehensively deals with the science and biomedical engineering formulations of cardiology. As a textbook, it addresses the teaching, research, and clinical aspects of cardiovascular medical engineering and computational cardiology. The books consists of two sections. The first section deals with left ventricular

Advances of cardiovascular engineering prompt one to consider innovative device technology - that is, the development of new replacement heart valves or engineering of a totally implantable energy source for an artificial heart. However, these kinds of advances have often proved unable to achieve a long-lasting benefit as the cardiovascular field has matured so fast. Cardiovascular engineering has matured to the point where a major innovation must not only function, but must continuously function better than existing devices. This is difficult to accomplish in the complex cardiovasculature system, in which energy source, biocompatibility, compliance, and functionality all must be considered. The maturation of the field is evident from the fact that many engineered prosthetic systems perform well - for example, heart valves function for long periods of time, large-vessel vascular grafts are quite adequate, extracorporeal membrane oxygenation has significantly prolonged the feasible length of heart bypass and other surgical operations, and total artificial hearts can be used as a bridge to transplant without serious complications, yet none of these systems is as good as the natural ones it replaces. The reasons for this are many and incompletely understood. The next stage of progress must be better to alterations understandings of the various components of vasculature and their response by our devices, be they at the micro- or macro-circulatory levels, in the blood, or associated with the vascular wall.

Biomedical Engineering Modeling of Pancreatic, Respiratory, and Renal Regulatory Systems, and their Medical Assessments addresses the need for biomedical engineering to provide physiological analysis of organ systems and their medical applications to help enable quantitative formulation of physiological systems and defining their functions and dysfunctions, leading to precision diagnostics of diabetes, lung diseases, and kidney failure, often in the form of non-dimensional indices. The book chapters also deal with treatment systems, namely automated insulin infusion systems, hemodialysis, and peritoneal dialysis. The book is formulated to solve many physiological, bioengineering, and medical problems. Covers foundational concepts of the emerging fields of quantitative physiology and computational medicine, developing the biomedical engineering modeling of three important organ systems: pancreas, lungs, and kidneys Provides readers with detailed understanding of novel biomedical engineering strategies in key areas, such as pancreatic system engineering, glucose-insulin regulatory system engineering, pulmonary system engineering, and renal system engineering Provides in-depth technical coverage of computational modeling techniques and applied mathematics for these important physiological systems, including differential equations and the associated MATLAB datasets for all applied diagnostic and treatment examples

With this book, it was not our intention to provide a complete "textbook" on axial pumps and their use as temporary cardiac assist systems. It is more a sharing of experiences with a novel left-ventricular assist system, the Hemopump, as it was developed by R.K. Wampler. This device, marketed by Johnson & Johnson Interventional Systems, has not yet been widely used and accepted in clinical practice. It was offered to us some time ago to study its applicability in the experimental setting. At the moment, it is under investigation in many centers and it is commercially available. However, as with any other cardiac assist system, the axial pump has its own advantages and limitations. Needless to say, critical analysis of such a novel device is mandatory and, therefore, we are grateful to our colleagues who were willing to contribute to this book. They present, discuss, and analyze their experimental and clinical experience with the Hemopump and focus on side-effects, deficiency and efficiency of this device which, by virtue of its simplicity is revolutionary. Leuven, Belgium, 1991 Willem Flameng v Contributors H. Reul, Ph. D. Helmholtz Institute for Biomedical Engineering at the RWTH Aachen, Pauwelstrasse 30, D-5100 Aachen, FRG R. IC. Wample~ ~. D. Nimbus ~edical, Inc., 2890 ICilgore Road, Rancho Cordova, California 95670, USA IC.-H. Scholz, ~. D. ICliniken der Universitat Gottingen, Fachbereich ~edizin, Zentrum Innere ~edizin Abt. ICardiologie, Robert ICochstrasse 40, D-3400 Gottingen, FRG P. Wouters, ~. D.