David Kuter and a host of leading international researchers summarize in one volume all the knowledge of thrombopoietins (TPO) available today. The distinguished experts review the history of the search to discover TPO, describe the molecular and biological characteristics of this new molecule, and present the results of the preclinical animal experiments that will guide clinical use of this new hormone. Along the way they provide the most recent and comprehensive guide to the biology of megakaryocytes and platelets.

Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from 142 world experts from 18 countries. This award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic mechanisms of platelets and the role of platelets in thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis and cancer. It also provides start-of-the-art presentations by hematologists, cardiologists, stroke physicians, blood bankers, pathologists and other clinicians on platelet function testing, disorders of platelet numbers and function, antiplatelet therapy and therapy to increase platelet numbers and/or function. Since the publication of the Third Edition of Platelets, there has been a rapid expansion of knowledge in both basic biology of platelets and the clinical approach to platelet-related diseases. This Fourth Edition of Platelets draws all this information into a single, comprehensive and authoritative resource. - Comprehensive and definitive source of state-of-the-art knowledge about platelets - Integrates the entire field of platelet biology, pathophysiology, and clinical medicine - Written for clinicians, pathologists and scientists by 142 world-renowned experts from 18 countries - Completely revised and updated, with 11 new chapters on topics such as platelet glycobiology, the platelet transcriptome, platelet inhibitory receptors, platelet function testing in clinical research trials, therapeutic platelet-rich plasma in wound healing, and new antiplatelet drugs - Full color textbook with over 250 illustrations and 15,000 references

This book contains a collection of papers dealing with various aspects of the biology and aquaculture of the large branchiopod crustacea; the Anostraca, Conchostraca, and Notostraca. Included are many of the papers presented at the Second International Large Branchiopod Symposium convened in Ulm, Germany, 30 July--3 August 1993. Additional manuscripts contributed by colleagues who were unable to attend are also included. A special feature of this volume is a checklist of the Anostraca, including information on distribution, location of type material, taxonomic problems, and literature references.

This book compiles for the first time the development of echinoderm research in Latin America. The book contains 17 chapters, one introductory, 15 country chapters, and a final biogeographic analysis. It compiles all the investigations published in international and local journals, reports, theses and other gray literature. Each chapter is composed of 7 sections: introduction describes the marine environments, and main oceanographic characteristics, followed by a history of research account divided by specific subjects. The next section addresses patterns of distribution and diversity. A specific section would explain fishery or aquaculture activities. The next sections deal with environmental and anthropogenic threats that are affecting echinoderm, and any conservation or management action. Finally, a section with conclusions, needs and new lines of research. The book will include two appendixes with species lists of all echinoderms with bathimetric data, habitat and distribution.