Hardbound. Although problems relating to hyperthermia and heat stroke are well known since biblical times, until now the influence of heat or hyperthermia on the central nervous system has not been well documented. This book is the first to describe in detail the influences of hyperthermia on the CNS using the modern technology which has developed in the last 50 years in neuroscience. Hyperthermia is a common feature during fever, radiotherapy of tumours and exercise in hot environment. Statistically, hyperthermia and/or heat stroke is currently recognised as the third largest killer in America after head and spinal trauma and heart failure. However, studies on the mechanisms of heat-induced death or damage to the CNS are still lacking. This book aims to define the probable mechanisms of brain damage in hyperthermia which could be responsible for death of victims. Rational therapeutic measures based on the experimental findings are also described.The m

The book traces the story of the brain throughout evolution and shows how the control of body temperature as a survival mechanism was achieved.

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

The effects of global warming on human health factors with special regards to our brain function are still not well understood. There is an urgent need to expand our knowledge on the effects of hot environment on our brain functions in healthy and in diseased populations. It is still unclear whether infectious events, traumatic injuries, metabolic diseases, carcinogenic events, cardiovascular and respiratory functions will be adversely affected by the rise in global temperature or whether environmental pollutants, such as nanoparticles entered into our body system will produce more damage at high ambient temperatures. This book aims to answer these questions based on recent research carried out by top experts in the field from the USA (11 chapters), Europe (8) chapters), the Middle East (3 chapters), Asia (2 chapters) and Canada (1). These chapters are written in review style and embedded with the author's new and original data in relation to the current knowledge in the field. The book is highly interesting to the first time readers, beginners and students alike as well as provides in-depth knowledge to the professionals. In addition, prospects for future research and recommendations are clearly indicated in each chapter for future growth of the subject in this highly emerging new discipline. Describes the importance of brain temperature and hyperthermia in disease processes Presents research on the first observations on Nanoparticles that worsen the outcome of hyperthermia Discusses the effects of hyperthermia on the blood-brain and blood-cerebrospinal fluid barriers

Brain Facts is a primer on the brain and nervous system, published by the Society for Neuroscience. Brain Facts is a valuable resource for educators, students, and anyone interesting in learning about neuroscience. Download an audio recording of Brain Facts today, available on BrainFacts.org and through iTunes U. The brain is the most complex biological structure in the known universe. It is a topic rich with exciting new discoveries, continuing profound unknowns, and critical implications for individuals, families, and societies. Learn more about the brain and nervous system through articles, images, videos, and more on BrainFacts.org, a public information initiative of The Kavli Foundation, the Gatsby Charitable Foundation, and the Society for Neuroscience.

This book reviews the research pertaining to nutrient requirements for working in cold or in high-altitude environments and states recommendations regarding the application of this information to military operational rations. It addresses whether, aside from increased energy demands, cold or high-altitude environments elicit an increased demand or requirement for specific nutrients, and whether performance in cold or high-altitude environments can be enhanced by the provision of increased amounts of specific nutrients.

Brain-derived Neurotrophic Factor (BDNF) is a biomarker of cognitive function that is released into the blood stream following physical activity, and cognitive function is in inhibited by environmental temperatures that are hot and cold. Purpose: To evaluate the activity-dependent release of BDNF in different environmental temperatures. Methods: Recreationally trained males (n = 12, age: 25 ± 4 yr, height: 178 ± 5 cm, weight: 79.2 ± 12.8 kg, %BF 14.5 ± 3.5%, VO2peak: 4.29 ± 0.82 L ̇min-1 ) each completed three trials consisting of cycling for one hour at 60% of the workload associated with VO2peak at three different temperatures, hot (H) at 33°C, cold (C) at 7°C, and room temperature (RT) at 20°C. Blood was taken from the antecubital vein pre-exercise, immediately post-exercise, and following a three hour recovery. Respiratory gasses were collected periodically throughout exercise and recovery. Results: BDNF was elevated immediately following an exercise bout (1711 ? 766 pg ̇ml-1) regardless of temperature from pre-exercise (1257 ? 653 pg ̇ml-1, p = 0.001) and returned to basal levels following three hours of recovery (1289 ? 650 pg ̇ml-1, p = 0.786). There was no effect (p > 0.05) of temperature on BDNF following the exercise bout. Plasma glucose was elevated in H (6.159 ± 0.939 mmol) over C (5.261 ± 0.593 mmol, p = 0.035) and RT (5.212 ± 0.546, p = 0.008). VO2 was elevated during exercise in H (3.01 ± 0.45 L ̇min-1) over C (2.67 ± 0.35 L ̇min-1, p = 0.005) and RT (2.80 ± 0.38 L ̇min-1, p = 0.001). There was no relationship between BDNF and plasma glucose (p > 0.05) or VO2 across any time point or temperature (p > 0.05). Conclusion: With aerobic activity, BDNF is elevated; however the release of BDNF is not affected by different environmental temperatures during exercise.