An estimated 80 million people live with a neurodegenerative disease. That number is expected to increase rapidly as populations age, lifespans increase, and exposure to toxins rises. Despite decades of research and billions in funding, there are no medications that can slow, much less stop, the progress of these diseases. This is because diseases such as Parkinson's and Alzheimer's do not exist in biology. Yet, hundreds of clinical trials around the world are examining the potential of single therapies in thousands of people sharing one of these labels. Compounding the problem, these therapies were developed on evidence from models that do not come close to capturing the complexity of these diseases in the affected humans. These practices must end. Brain Fables is a call to refocus on understanding living and aging to create the personalized treatments each affected individual desperately needs.

Chevalier (anthropology, Carlton U., Ottawa) begins a series of three non-technical volumes on connections between brain, sign, and mind, seeking answers at the intersection between neuropsychology, semiotics, and philosophy. Here he explores symbols ranging from western naming practices to botanical imageries appearing in Genesis, English poetry, and native Mexican mythology.Distributed in the US by CUP Services. Annotation copyrighted by Book News, Inc., Portland, OR

With no biological boundaries between neurodegenerative diseases as defined today, Brain Fables offers a blueprint for precision medicine.

How does the brain control the rest of the body? How does it enable the senses, regulate speech, affect balance, and influence sleep and dreams? These 30 full-page illustrations to color help explain every aspect of the brain's big job, from communicating with the central nervous system to retaining memories.

How new biomedical technologies—from prenatal testing to gene-editing techniques—require us to imagine who counts as human and what it means to belong. From next-generation prenatal tests, to virtual children, to the genome-editing tool CRISPR-Cas9, new biotechnologies grant us unprecedented power to predict and shape future people. That power implies a question about belonging: which people, which variations, will we welcome? How will we square new biotech advances with the real but fragile gains for people with disabilities—especially when their voices are all but absent from the conversation? This book explores that conversation, the troubled territory where biotechnology and disability meet. In it, George Estreich—an award-winning poet and memoirist, and the father of a young woman with Down syndrome—delves into popular representations of cutting-edge biotech: websites advertising next-generation prenatal tests, feature articles on “three-parent IVF,” a scientist's memoir of constructing a semisynthetic cell, and more. As Estreich shows, each new application of biotechnology is accompanied by a persuasive story, one that minimizes downsides and promises enormous benefits. In this story, people with disabilities are both invisible and essential: a key promise of new technologies is that disability will be repaired or prevented. In chapters that blend personal narrative and scholarship, Estreich restores disability to our narratives of technology. He also considers broader themes: the place of people with disabilities in a world built for the able; the echoes of eugenic history in the genomic present; and the equation of intellect and human value. Examining the stories we tell ourselves, the fables already creating our futures, Estreich argues that, given biotech that can select and shape who we are, we need to imagine, as broadly as possible, what it means to belong.

Fun stories to teach your kids about money. "Perhaps the most cleverly written, and delightful to read, financial education book" J.J. Wenrich (Author and Financial Advisor) When Grandpa Jack was a young man, he went on an adventure to a faraway island in search of gold. Whilst he was on the island he discovered 'The Three Rules of Wealth'. These rules helped him to become a very wealthy man. As Gail shares her Grandpa’s adventures, your kids will learn: - The difference between being 'Rich' and being 'Wealthy' - How to earn money - The importance of saving their money - How to grow their money (investing) - That patience is the superpower of the wealthy - Why they should avoid gambling, scams and (bad) debt Your kids will also have to try and solve Grandpa's Mystery Code as they answer short questions to recap on what they have learnt throughout the book. “This book should be in every school library” Kevin Gatland OBE "I would give this book 5 stars out of 5 ... It’s great to read aloud!" Isla Manson, avid reader, age 11