Trauma Induced Coagulopathy

Trauma Induced Coagulopathy
Title Trauma Induced Coagulopathy PDF eBook
Author Hunter B. Moore
Publisher Springer Nature
Pages 802
Release 2020-10-12
Genre Medical
ISBN 3030536068

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The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.

Fluid Resuscitation

Fluid Resuscitation
Title Fluid Resuscitation PDF eBook
Author Institute of Medicine
Publisher National Academies Press
Pages 207
Release 1999-10-05
Genre Medical
ISBN 0309172799

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Historically, 20% of all injured combatants die on the battlefield before they can be evacuated to a field hospital. Blood lossâ€"hemorrhageâ€"is the single major cause of death among those killed in action whose lives might otherwise be saved. Fluid resuscitation and the treatment of hypovolemia (the abnormally decreased volume of circulating fluid in the body) offer the greatest opportunity for reducing mortality and morbidity associated with battlefield casualties. In Fluid Resuscitation, a committee of experts assess current resuscitation fluids and protocols for the treatment of combat casualties and make recommendations for future research. Chapters focus on the pathophysiology of acute hemorrhagic shock, experience with and complications of fluid resuscitation, novel approaches to the treatment of shock, protocols of care at the site of injury, and future directions for research. The committee explicitly describes the similarities and differences between acute medical care during combat and civilian emergency trauma care. Fluid Resuscitation should help energize and focus research in both civilian and military emergency care and help save the lives of citizens and soldiers alike.

Regulation of Tissue Oxygenation, Second Edition

Regulation of Tissue Oxygenation, Second Edition
Title Regulation of Tissue Oxygenation, Second Edition PDF eBook
Author Roland N. Pittman
Publisher Biota Publishing
Pages 117
Release 2016-08-18
Genre Medical
ISBN 1615047212

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This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Modern Monitoring in Anesthesiology and Perioperative Care

Modern Monitoring in Anesthesiology and Perioperative Care
Title Modern Monitoring in Anesthesiology and Perioperative Care PDF eBook
Author Andrew B. Leibowitz
Publisher Cambridge University Press
Pages 434
Release 2020-05-07
Genre Medical
ISBN 1108581803

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Close monitoring of patients during anesthesia is crucial for ensuring positive treatment outcomes and patient safety. The increasing availability of new technologies and the repurposing of older monitors means more patient data is at anesthesiologists' fingertips than ever before. However, this flood of options can be overwhelming. A practical resource for understanding this array of clinical monitoring options in anesthesia, this important text focuses on real-world applications in anesthesia and perioperative care. Reviewing the evidence for improved patient outcomes for monitoring technology, neurological monitoring, echocardiography systems and ultrasound are amongst the techniques covered in a head-to-toe approach. Statistics used by manufacturers to gain approval for their technology are discussed, as well as the under-appreciated risks associated with monitoring such as digital distraction. Future monitoring technologies including wearable systems are explored in depth. Focusing on applied practice, this book is an essential text for front-line healthcare professionals in anesthesia.

Tumescent Technique

Tumescent Technique
Title Tumescent Technique PDF eBook
Author Jeffrey A. Klein
Publisher
Pages 494
Release 2000
Genre Medical
ISBN

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TUMESCENT TECHNIQUE is the definitive reference on all aspects of the tumescent technique of anesthesiology used in liposuction. Written by the inventor of the tumescent technique, this resource explains the pathophysiology, complications, pharmacology, and the different methods used to achieve great cosmetic results. Step-by-step instructions demonstrate how to perform this procedure on all areas of the body. Complications and postoperative care are also addressed. * Written by Dr. Klein, a leading expert in the field and the physician who invented and perfected the technique. * Provides step-by-step instructions for administering the local anesthesia with a practical, easy-to-follow approach. * Discusses tumescent liposuction techniques for each body region, addressing procedures, guidelines, and complications for each. * Covers complications and how to avoid them, preventing problems before they arise. * Provides detailed illustrations of techniques and before and after photographs to allow you to see expected results.

WHO Guidelines for the Management of Postpartum Haemorrhage and Retained Placenta

WHO Guidelines for the Management of Postpartum Haemorrhage and Retained Placenta
Title WHO Guidelines for the Management of Postpartum Haemorrhage and Retained Placenta PDF eBook
Author World Health Organization
Publisher World Health Organization
Pages 62
Release 2009
Genre Family & Relationships
ISBN 9241598514

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Diagnosis of PPH -- Management of atonic PPH -- Management of retained placenta -- Choice of fluid for replacement or resuscitation -- Health systems and organizational interventions -- PPH care pathways -- Research implications -- Plans for local adaptation of the recommendations -- Plans for supporting implementation of these recommendations -- GRADE tables.

Damage Control Resuscitation

Damage Control Resuscitation
Title Damage Control Resuscitation PDF eBook
Author Philip C. Spinella
Publisher Springer
Pages 379
Release 2019-08-12
Genre Medical
ISBN 3030208206

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This book provides a comprehensive overview of damage control resuscitation (DCR), an evidence-based approach to the resuscitation of patients with severe life-threatening hemorrhage (LTH). It focuses on both civilian and military applications as DCR is utilized in civilian trauma situations as well as combat casualty care settings. The book covers the history of fluid resuscitation for bleeding, epidemiology of severe traumatic injuries, prediction of life-threatening hemorrhage, pathophysiology and diagnosis of blood failure, and permissive hypotension. Chapters provide in-depth detail on hemostatic resuscitation principles, dried plasma, dried platelet surrogates, and recent developments in frozen red blood cells and oxygen carriers. The book also discusses how DCR principles can be used in a variety of situations such as when there are large numbers of patients with hemorrhagic lesions, non-trauma scenarios, and on distinct populations such as children. Finally, it concludes with a discussion of training and education methods for the implementation of DCR and remote DCR principles as well as learning healthcare system principles to facilitate the implementation of DCR and ultimately improve outcomes for patients with life-threatening hemorrhage. Damage Control Resuscitation: Identification and Treatment of Life-Threatening Hemorrhage is an essential resource for physicians and related professionals, residents, nurses and medical students in emergency medicine, anesthesia, surgery, and critical care, as well as civilian and military EMS providers.