This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Although many things can go wrong in the brain, this book also shows that our brain is strong. It highlights the key findings that can be seen on magnetic resonance imaging (MRI) and computed tomography (CT) scans, including those related to normal brain aging and common diseases such as brain infarcts, fractures of the skull as well as fractures and tumors of the vertebral column. It offers insights into brain MRI and CT scans, enabling readers to interpret the key findings.

Veins of Devotion details recent collaborations between guru-led devotional movements and public health campaigns to encourage voluntary blood donation in northern India. Focusing primarily on Delhi, Jacob Copeman carefully situates the practice within the context of religious gift-giving, sacrifice, caste, kinship, and nationalism. The book analyzes the operations of several high-profile religious orders that organize large-scale public blood-giving events and argues that blood donation has become a site not only of frenetic competition between different devotional movements, but also of intense spiritual creativity.

By turns harrowing, moving, and ultimately redemptive, this is a war story -- a war that rages out of control on the streets of the United States, claiming the lives of our loved ones and neighbors. In this memoir, complete with child soldiers, unspeakable violence, and eventual salvation, we witness the journey of an East Coast member of the notorious Bloods gang coming to terms with the lost boy he was and the transformation into the man he wants to become. Unlike the child warriors of Mozambique and Sierra Leone, gang members and the wars they wage are the United States' homegrown nightmare. Lacking protection, support, or any alternatives, Dashaun Morris is forced into battle for the first time at age eleven, in the streets of Phoenix, when a friend's older brothers put him in a car filled with 40s and weed smoke, put a gun in his hands, then make him point it at the men on the corner and squeeze the trigger. The targets are Crips, of course, and, as Morris writes, "In the darkness of the streets, my childhood is murdered.... I am reborn -- a gangster." In this haunting, violent memoir, Morris takes us through an American childhood turned grotesquely inside out. In the fourth grade, he loses his first friend in a drive-by shooting. By high school he is the man, a champion on the football field by day and a reputable banger on his 'hood turf by night. Living the life of a gang banger, Morris does it all -- drug dealing, jacking, and continuing the aimless war with rival gang members -- almost opening fire one night on a close friend, a cheerleader, as she hangs out with young men he mistakes for Crips. He eventually makes it to college on a football scholarship, but on the verge of being drafted by the NFL, Morris can't escape his gang-banging mentality and gets caught up in crimes that snatch away all future hopes. Sitting in a prison cell, he anticipates the birth of his first child while counting the friends he's buried. War of the Bloods in My Veins is part of Morris's redemption, a cry to his brothers that gang life is mental illness. It is a rare and brutally honest look into the relentless storm of abandonment, violence, crime, death, and the endless rush toward the complete and utter self-annihilation that plagues the lives of the young "soldiers" who die every day in our streets.

Since its U.S. debut a quarter-century ago, this brilliant text has set a new standard for historical scholarship of Latin America. It is also an outstanding political economy, a social and cultural narrative of the highest quality, and perhaps the finest description of primitive capital accumulation since Marx. Rather than chronology, geography, or political successions, Eduardo Galeano has organized the various facets of Latin American history according to the patterns of five centuries of exploitation. Thus he is concerned with gold and silver, cacao and cotton, rubber and coffee, fruit, hides and wool, petroleum, iron, nickel, manganese, copper, aluminum ore, nitrates, and tin. These are the veins which he traces through the body of the entire continent, up to the Rio Grande and throughout the Caribbean, and all the way to their open ends where they empty into the coffers of wealth in the United States and Europe. Weaving fact and imagery into a rich tapestry, Galeano fuses scientific analysis with the passions of a plundered and suffering people. An immense gathering of materials is framed with a vigorous style that never falters in its command of themes. All readers interested in great historical, economic, political, and social writing will find a singular analytical achievement, and an overwhelming narrative that makes history speak, unforgettably. This classic is now further honored by Isabel Allende's inspiring introduction. Universally recognized as one of the most important writers of our time, Allende once again contributes her talents to literature, to political principles, and to enlightenment.