This issue of the Psychiatric Clinics edited by Dr. John Beyer is dedicated to the topic of Bipolar Depression, from the genetics of the disorder, to the therapeutic options, to treatment in special populations. Articles in this issue include, but are not limited to: Differences in Bipolar and Unipolar Depression, Suicide and Bipolar Disorder, Social Relationships, Support, and Life Events in Bipolar Disorder, Treatment of Bipolar Depression in Pregnancy and the Post-Partum Period, Psychotherapy for Bipolar Depression, Cognition, Dementia, and Bipolar Depression, and Genetics of Bipolar Disorder.

In this issue of Psychiatric Clinics, guest editors Drs. Manish K. Jha and Madhukar H. Trivedi bring their considerable expertise to the topic of Treatment-Resistant Depression. Treatment-resistant depression (TRD), when patients experience an inadequate response to standard treatment plans, is a relatively common occurrence in clinical practice. In this issue, top experts shed light on this difficult-to-treat disorder, helping healthcare professionals improve outcomes for their patients with TRD. - Contains 15 practice-oriented topics including overview of TRD; improving depression outcomes through measurement-based care; approach to diagnosis and treatment for difficult-to-treat depression; TRD in children and in the elderly; neuroimaging biomarkers of treatment-resistant depression; the role of psychedelics in TRD; and more. - Provides in-depth clinical reviews on treatment-resistant depression, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Psychiatric Clinics, edited by Drs. Dan Blazer and Susan Schultz, will cover a number of important aspects of Geriatric Psychiatry. Topics in this issue include, but are not limited to: Delirium in the elderly; Depression and cardiac disease in later life; Schizophrenia in later life; Anxiety Disorders in later life; Neurological changes and depression; Behavioral Changes with Alzheimer’s Disease and Vascular Dementia; Palliative Care in Dementia and Chronic Mental Illness; Collaborative Care for the elderly with psychiatric disorders; and Post Traumatic Stress Disorders in the elderly.

Get a quick, expert overview of the key issues surrounding best practices and current consensus on major depressive disorder (MDD). This concise resource by Drs. Roger S. McIntyre, Carola Rong, Mehala Subramaniapillai, and Yena Lee consolidates today's available information on this complex topic into one convenient resource, making it an ideal, easy-to-digest reference for both psychiatrists and primary care physicians. - Covers genetics and epigenetics, brain structural abnormalities, cognition, neuroendocrine alterations, and inflammatory abnormalities as they relate to MDD. - Contains chapters on psychiatric comorbidity, pharmacological treatments, neuromodulatory treatments, lifestyle interventions, internet-based/technology-based interventions, and glutamate alterations.

Bipolar disorders were once considered rare in children and adolescents. A growing body of scientific evidence now suggests that they may be more prevalent in this group than previously believed. At the same time, the practitioner faces significant clinical challenges in both the assessment processes and also the implementation of a treatment plan. A paucity of treatment manuals and pharmacological algorithms providing practical guidance makes the task of the clinician even more difficult, despite the fact that more is known about the assessment, neurobiology and treatment of children and adolescents with bipolar disorder than ever before. Written by three distinguished experts, this book conveys to clinicians all the information currently available in this area. They review both the neuroscience and also the integration of rational, practical, pharmacological and psychosocial interventions. Based on what is known, a sound approach to the assessment of these youngsters can be developed. Similarly, available evidence allows practitioners to ground their treatment protocols solidly on scientific knowledge. Concise and authoritative, Pediatric Bipolar Disorders will give the reader a practical approach to both the art and science of providing the best possible clinical care to children and adolescents with the disorder. This book is written primarily for clinical psychiatrists, but will also be of interest to non-specialist doctors and other members of the health care team.

Brain disordersâ€"neurological, psychiatric, and developmentalâ€"now affect at least 250 million people in the developing world, and this number is expected to rise as life expectancy increases. Yet public and private health systems in developing countries have paid relatively little attention to brain disorders. The negative attitudes, prejudice, and stigma that often surround many of these disorders have contributed to this neglect. Lacking proper diagnosis and treatment, millions of individual lives are lost to disability and death. Such conditions exact both personal and economic costs on families, communities, and nations. The report describes the causes and risk factors associated with brain disorders. It focuses on six representative brain disorders that are prevalent in developing countries: developmental disabilities, epilepsy, schizophrenia, bipolar disorder, depression, and stroke. The report makes detailed recommendations of ways to reduce the toll exacted by these six disorders. In broader strokes, the report also proposes six major strategies toward reducing the overall burden of brain disorders in the developing world.

This issue of Psychiatric Clinics of North America, edited by Drs. Frank Yeomans and Kenneth Levy, will offer a comprehensive review of key topics of importance in the study of Borderline Personality Disorder. The series is led by our Consulting Editor, Dr. Harsh Trivedi of Sheppard Pratt Health System. This issue will explore the following topics: Conceptual models, Diagnosis and assessment, Differential diagnosis, Community and Clinical Epidemiology, Comorbidity, Longitudinal Course, Neuroscience and social cognition, Attachment, Psychotherapy and medication treatment research, Psychotherapy with children and adolescents, and Family and patient perspectives, among others.