Biotechnological Production of Bioactive Compounds provides insights on the most recent innovations, trends, concerns, solutions and practical challenges encountered in the fields of enzyme technology and nanobiotechnology for the production of bioactive materials with extra health benefits. As nanobiotechnology has improved the bioactive extraction process significantly, many bioactives, including bioflavonoids, omega-3 fatty acids, biopigments and low calorie sugar substitutes are a pivotal part of the food industry. The book highlights the production of extra health benefits "bioactives'' from plants and microbes and explains how the extraction efficiency of bioactives molecules improves significantly with the recent advances in nanobiotechnology. Researchers in the fields of biochemical engineering, biotechnology, bioremediation, environmental sustainability and those in pharma industries will find the information in this book very helpful and illuminating. - Outlines technological advances in bioactives extraction - Covers bioflavonoids, biopigments, omega-3-fatty acids and low sugar substitutes - Explains the mechanisms of Green cargo (biogenic nanoparticles) for the delivery of bioactive molecules

This reference work provides a comprehensive review of cell and tissue differentiation and its role in the formation of specific secondary metabolites. Divided into five sections, this book covers the main cellular processes involved in the biosynthesis of secondary metabolites. Chapters from expert contributors offer specific case studies of cell and tissue differentiation, examines secondary metabolites in shoot and root cultures, and present new scientific insights and original technologies with applications in medicinal plants and in plant biotechnology. Students, scholars and researchers with an interest in the fields of botany, agriculture, pharmacy, biotechnology and phytochemistry will find this book an important account. This book will also engage professionals working in plant-based industry.

Plants are a source of bioactive compounds and specialty chemicals such as ginsenosides; paclitaxel, artemisinin, veregen and nutraceuticals. Biopharmaceuticals are important in human healthcare, and herbal actives are gaining importance all over the world. With natural resources dwindling, in vitro production of secondary compounds on a commercial scale is being more and more required. The difficulties that are increasingly encountered in procuring ample supply of raw plant material because of drastic decrease in natural resources have prompted the adaptation of in vitro technology for commercial production of substances of medicinal importance. Besides providing an alternative technology to bypass the above difficulties, the plant tissue culture (used in a broad sense to include cell, tissue and organ culture) offers many advantages. In vitro technology also facilitates novel means of conserving the genetic diversity of the germplasm of medicinal plants through cryopreservation, and production of novel compounds through biotransformation, somatic hybridization and selective gene transfer through recombinant DNA technology for enhancing the metabolite production. Biotechnological production of bioactive phytochemicals of medicinal value covers a broad variety of methods for secondary metabolites production (both pharmaceuticals and cosmeceuticals), compiling state-of-the-art material about the current knowledge of in vitro production for a large number of bioactive phytochemicals. - Compiles state-of-the-art material about in vitro production for several bioactive phytochemicals - Incorporates the most recent developments in the field - Covers a broad variety of secondary metabolites

Functional and Preservative Properties of Phytochemicals examines the potential of plant-based bioactive compounds as functional food ingredients and preservative agents against food-spoiling microbes and oxidative deterioration. The book provides a unified and systematic accounting of plant-based bioactive compounds by illustrating the connections among the different disciplines, such as food science, nutrition, pharmacology, toxicology, combinatorial chemistry, nanotechnology and biotechnological approaches. Chapters present the varied sources of raw materials, biochemical properties, metabolism, health benefits, preservative efficacy, toxicological aspect, safety and Intellectual Property Right issue of plant-based bioactive compounds. Written by authorities within the field, the individual chapters of the book are organized according to the following practical and easy to consult format: introduction, chapter topics and text, conclusions (take-home lessons), and references cited for further reading. - Provides collective information on recent advancements that increase the potential use of phytochemicals - Fosters an understanding of plant-based dietary bioactive ingredients and their physiological effects on human health at the molecular level - Thoroughly explores biotechnology, omics, and bioinformatics approaches to address the availability, cost, and mode of action of plant-based functional and preservative ingredients

Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.

The bioactive compounds of plants have world-wide applications in pharmaceutical, nutraceutical and food industry with a huge market. In this book, a group of active researchers have addressed on the most recent advances in plant cell and organ cultures for the production of biomass and bioactive compounds using bioreactors. Tremendous efforts have been made to commercialize the production of plant metabolites by employing plant cell and organ cultures in bioreactors. This book emphasizes on the fundamental topics like designing of bioreactors for plant cell and organ cultures, various types of bioreactors including stirred tank, airlift, photo-bioreactor, disposable bioreactor used for plant cell and organ cultures and the advantages and disadvantages of bioreactor cultures. Various strategies for biomass production and metabolite accumulation have been discussed in different plant systems including Korean/Chinese ginseng, Siberian ginseng, Indian ginseng, Echinacea, St. John’s wort, Noni, Chinese licorice, Caterpillar fungus and microalgae. Researches on the industrial application of plant cells and organs with future prospects as well as the biosafety of biomass produced in bioreactors are also described. The topics covered in this book, such as plant cell and organ cultures, hairy roots, bioreactors, bioprocess techniques, will be a valuable reference for plant biotechnologists, plant biologists, pharmacologists, pharmacists, food technologists, nutritionists, research investigators of healthcare industry, academia, faculty and students of biology and biomedical sciences. The multiple examples of large-scale applications of cell and organ cultures will be useful and significant to industrial transformation and real commercialization.

This book covers the recent innovations relating to various bioactive natural products (such as alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, volatile oils, fixed oils, fats and waxes, proteins and peptides, vitamins, marine products, camptothecin, piperines, carvacrol, gedunin, GABA, ginsenosides) and their applications in the pharmaceutical fields related to academic, research and industry.