This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.

This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.

Continued advances in cardiology have led to unprecedentedscientific progress in recent years. However, no matter howadvanced the science, the successful application of interventionalcardiology relies upon a practitioner’s ability to approachinterventional techniques competently and confidently in everysituation. Fully updated and featuring new chapters and additional tips andtricks, this latest edition of Dr Nguyen, Colombo, Hu, Grines, andSaito’s celebrated book provides a complete yet concise guideto practical interventional cardiology that deserves a place inevery cardiac laboratory. Culled from the personal experience ofover fifty international experts, the book incorporates more than500 practical tips and tricks for performing interventionalcardiovascular procedures. Each strategic or tactical move isgraded by complexity level and described in a simple, step-by-stepapproach that includes guidance on how to overcome practicaldifficulties, providing a comprehensive resource that can benefitboth beginner or experienced operators. As well as covering the latest developments in interventionalcardiology, this third edition includes technical tips that promoteuser-friendly performance, low complication rates, cost- andtime-efficient approaches and cost- and time-effective selection ofdevices to help optimize the practice of modern interventionalcardiology.

The development and application of bioactive nano-structured constructs for tissue regeneration is the focus of the research summarised in this thesis. Moreover, a particular focus is the rational use of supercritical carbon dioxide foaming and electrospinning technologies which can lead to innovative polymeric bioresorbable scaffolds made of hydrolysable (both commercial and ‘ad-hoc’ synthesized) polyesters. Mainly, the author discusses the manipulation of polymer chemical structure and composition to tune scaffold physical properties, and optimization of scaffold 3D architecture by a smart use of both fabrication techniques. The multidisciplinary nature of this research is imperative in pursuing the challenge of tissue regeneration successfully. One of the strengths of this thesis is the integration of knowledge from chemistry, physics, engineering, materials science and biomedical science which has contributed to setting up new national and international collaborations, while strengthening existing ones.

Expert guidance from internationally recognized authorities, who provide clear and current updates on all aspects of interventional cardiology. This new edition; Contains a radically expanded chapter contents list presented in four clear sections; coronary interventions, interventional pharmacology, structural heart interventions, and endovascular therapy Includes 46 new chapters, including the latest advances in bioresorbable coronary stents, advanced transcatheter aortic valve replacement, MitraClip, new transcatheter mitral valve interventions, and more Chapters are templated for rapid referral, beginning with pathophysiological background and relevant pathology, moving to mechanisms of treatment, device description, procedural techniques, follow-up care, and ending with risks, contraindications and complications Multiple choice questions at the end of each chapter for self-assessment, a total of more than 400 MCQs in the book Features 19 procedural videos, hosted on a companion website

This book is intended as a guide for all cardiologists who are interested in coronary imaging and physiology, a sound understanding of which is vital for the optimal performance of appropriate coronary interventions. The basics of each relevant modality are presented, with clear explanation of clinical utility and evaluation of the evidence regarding clinical outcomes. All technical methods are described in detail, and the text is complemented by numerous helpful tables and illustrations. The effectiveness of intravascular coronary imaging in improving clinical outcomes is proven, and it is widely used for this purpose. Two modalities for intravascular coronary imaging are available in clinical practice: intravascular ultrasound (IVUS) and optical coherence tomography (OCT). For coronary physiology, the pressure wire-derived fractional flow reserve (FFR) provides information on the functional status of coronary trees. This technique and its clinical applications receive particular attention in the book, which also looks beyond FFR to FFR-CT, a method using computational fluid dynamics, and to invasive assessment of the microcirculation.

Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t