This book contains the proceedings of an international hearing-research conference held in Germany 2002. The conference brought together experts in genetics, molecular and cellular biology, physiology, engineering, physics, mathematics, audiology and medicine to synthesize and extend our understanding of how the cochlea works. Topics are discussed experimentally and theoretically at the molecular, cellular and whole-organ levels. Some of the topics are: mechanosensitivity of motor proteins; mechanochemical transduction by motor proteins; mechanoelectrical transduction in the stereocilia of hair cells; electromechanical transduction in the stereocilia, soma and synapses of hair cells; multidimensional vibration of the organ of Corti; and otoacoustic emissions. This book will be invaluable to researchers and students in auditory science.The proceedings have been selected for coverage in:• Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings)

The workshop brought together experts in genetics, molecular and cellular biology, physiology, engineering, physics, mathematics, audiology and medicine to present current work and to review the critical issues of inner ear function. A special emphasis of the workshop was on analytical model based studies. Experimentalists and theoreticians thus shared their points of view. The topics ranged from consideration of the hearing organ as a system to the study and modeling of individual auditory cells including molecular aspects of function. Some of the topics in the book are: motor proteins in hair cells; mechanical and electrical aspects of transduction by motor proteins; function of proteins in stereocilia of hair cells; production of acoustic force by stereocilia, mechanical properties of hair cells and the organ of Corti; mechanical vibration of the organ of Corti; wave propagation in tissue and fluids of the inner ear; sound amplification in the cochlea; critical oscillations; cochlear nonlinearity, and mechanisms for the production of otoacoustic emissions. This book will be invaluable to researchers and students in auditory science.

This unique compendium is devoted to flexoelectricity — the response of polarization to a strain gradient. The effect is analogous to piezoelectricity which is the response of polarization to strain itself. In contrast to piezoelectricity, which appears only in non-centrosymmetric materials, flexoelectric effect is allowed by symmetry in any materials. It becomes appreciable in nano-scale systems, where large strain gradients arise. The book discusses different nano-scale manifestations of the effect ranging from repulsion of acoustic and optic branches of materials to flexoelectricity in domain walls. It mainly caters for scientists, engineers and students.

Architects are used to designing visually. In order to expand their basic design tools, this book explores the interactions between sound, space, hearing, and architecture. To this end, the author uses contemporary and historic buildings and projects, but also fictional, philosophical, and theoretical approaches – the idea is not only to define sound as a source, but also as an instrument of architectural space. By introducing a metatheory of "critical hearing", designers are able to acoustically test their projects and contribute to their design with auditive input, already at the design stage.

The first volume in The Oxford Handbook of Auditory Science, The Ear serves both as an introduction and as a reference work for anyone interested in how 'hearing' happens. It will be a valuable resource, for anyone interested in the ongoing challenge, and adventure, of understanding the mysteries of the ear.

A physicist's guide to the phenomena of life Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology—from the discovery of DNA's structure to imaging of the human brain—have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles—the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes